BDB743742
TREM-1 (CD354) Mouse anti-Human, Brilliant Violet 711, Clone: 6B1, BD Optibuild™
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB743742-Each-of-1 | In Stock | ₹ 47,614.14 |
BDB743742 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,614.14
GST (18%): ₹ 8,570.545
Total Price: ₹ 56,184.685
Antigen
TREM-1 (CD354)
Clone
6B1
Conjugate
Brilliant Violet 711
Gene Alias
TREM1, Triggering receptor expressed on myeloid cells 1
Immunogen
Human Trem-1 Recombinant Protein
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification
Monoclonal
Concentration
0.2mg/mL
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Description
- The 6B1monoclonal antibody specifically binds to TREM-1 (Triggering Receptor Expressed on Myeloid Cells 1 or Triggering Receptor Expressed on Monocytes 1) which is also known as CD354
- CD354 is a type I transmembrane glycoprotein that belongs to the immunoglobulin superfamily
- CD354 is highly expressed by neutrophils and monocytes
- It is also reportedly expressed at lower levels by a variety of cells including subsets of T and B cells, NK cells and dendritic cells
- Its expression is upregulated on leucocytes in response to microbial lipopolysaccharide, eg, during microbial infections or sepsis
- CD354 activation triggers the release of proinflammatory cytokines and chemokines
- A soluble form of CD354 has been described that may play a protective role in some infectious disease states
- The antibody was conjugated to BD Horizon™ BV711 which is part of the BD Horizon Brilliant™ Violet family of dyes
- This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405nm and an acceptor dye with an Em Max at 711nm
- BD Horizon BV711 can be excited by the violet laser and detected in a filter used to detect Cy™5.5 / Alexa Fluor™ 700-like dyes (eg, 712/20nm filter)
- Due to the excitation and emission characteristics of the acceptor dye, there may be moderate spillover into the Alexa Fluor™ 700 and PerCP-Cy5.5 detectors
- However, the spillover can be corrected through compensation as with any other dye combination
- BV711 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an emission maximum at 711 nm
- This dye offers a very bright choice for the violet laser
- Due to the excitation and emission characteristics of the acceptor dye, there may be moderate spillover into the Alexa Fluor™ 700 and PerCP-Cy5.5 detectors
- BV711 will also have moderate spillover into the BD Horizon Brilliant™ Violet 786 detector.
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Antigen: TREM-1 (CD354)
Clone: 6B1
Conjugate: Brilliant Violet 711
Gene Alias: TREM1, Triggering receptor expressed on myeloid cells 1
Immunogen: Human Trem-1 Recombinant Protein
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
TREM-1 (CD354)
Clone:
6B1
Conjugate:
Brilliant Violet 711
Gene Alias:
TREM1, Triggering receptor expressed on myeloid cells 1
Immunogen:
Human Trem-1 Recombinant Protein
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: TREM-1 (CD354)
Clone: 6B1
Conjugate: Brilliant Violet 786
Gene Alias: TREM1, Triggering receptor expressed on myeloid cells 1
Immunogen: Human Trem-1 Recombinant Protein
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
TREM-1 (CD354)
Clone:
6B1
Conjugate:
Brilliant Violet 786
Gene Alias:
TREM1, Triggering receptor expressed on myeloid cells 1
Immunogen:
Human Trem-1 Recombinant Protein
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: TREM-1 (CD354)
Clone: 6B1
Conjugate: Brilliant Ultraviolet 395
Gene Alias: TREM1, Triggering receptor expressed on myeloid cells 1
Immunogen: Human Trem-1 Recombinant Protein
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
TREM-1 (CD354)
Clone:
6B1
Conjugate:
Brilliant Ultraviolet 395
Gene Alias:
TREM1, Triggering receptor expressed on myeloid cells 1
Immunogen:
Human Trem-1 Recombinant Protein
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: Vδ2 TCR
Clone: B6
Conjugate: Brilliant Violet 421
Gene Alias: TCR Vδ2
Immunogen: Human TCR Vδ2 Recombinant Protein
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
Vδ2 TCR
Clone:
B6
Conjugate:
Brilliant Violet 421
Gene Alias:
TCR Vδ2
Immunogen:
Human TCR Vδ2 Recombinant Protein
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ