BDB743842

CD148 Hamster anti-Mouse, Brilliant Violet 421, Clone: 8A-1, BD Optibuild™

Manufacturer: BD Biosciences

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Pack Size SKU Availability Price
Each of 1 BDB743842-Each-of-1 In Stock ₹ 34,224.00

BDB743842 - Each of 1

₹ 34,224.00

In Stock

Quantity

1

Base Price: ₹ 34,224.00

GST (18%): ₹ 6,160.32

Total Price: ₹ 40,384.32

Antigen

CD148

Clone

8A-1

Conjugate

Brilliant Violet 421

Gene Alias

Ptprj, R-PTP-J, BET, Byp, DEP-1, PTPbeta2, Ptpb2, R-PTP-eta, Scc-1, Scc1

Immunogen

Mouse CD148 Transfected Cell Line

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification

Monoclonal

Concentration

0.2mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species

Syrian Hamster

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Mouse

Isotype

IgG1

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Description

  • The 8A-1 monoclonal antibody specifically binds to CD148, which is also known as Protein tyrosine phosphatase receptor type J (Ptprj), Receptor-type tyrosine-protein phosphatase eta (R-PTP-eta, PTPη ), or Density-enhanced phosphatase-1 (DEP-1)
  • CD148 is a receptor-like tyrosine phosphatase that plays important roles in regulating cell growth, proliferation, differentiation, adhesion, and migration
  • It is expressed on a wide variety of cell types including epithelial cells, endothelial cells, and fibroblasts
  • For cells of hemopoietic origin, it is variably expressed on macrophages, neutrophils, dendritic cells, and on developing and mature B cells
  • CD148 is expressed on platelets and can regulate platelet activation
  • Although expressed at low levels on thymocytes and mature T cells, its expression is upregulated upon T cell receptor (TCR)-mediated stimulation and may play a role in regulating TCR signaling
  • CD148, along with CD45, are critical protein tyrosine phosphatases for regulating Src family kinase signaling networks in immune cells
  • The antibody was conjugated to BD Horizon™ BV421 which is part of the BD Horizon Brilliant™ Violet family of dyes
  • With an Ex Max of 407nm and Em Max at 421nm, BD Horizon BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50nm filter)
  • BD Horizon BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue conjugates
  • BV421 is a polymer-based dye excited by the violet laser and is one of the brightest fluorochromes offered by BD Biosciences
  • Conjugates are typically 10 times brighter than Pacific Blue™ conjugates and are often as bright as or brighter than PE conjugates
  • Due to nearly identical excitation and emission properties but different spillover characteristics, BD Horizon BV421, Pacific Blue™, and BD Horizon™ V450 cannot be used simultaneously.

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BD Biosciences

BDB743842

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Antigen:
CD148

Clone:
8A-1

Conjugate:
Brilliant Violet 421

Gene Alias:
Ptprj, R-PTP-J, BET, Byp, DEP-1, PTPbeta2, Ptpb2, R-PTP-eta, Scc-1, Scc1

Immunogen:
Mouse CD148 Transfected Cell Line

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Syrian Hamster

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG1

Img

BD Biosciences

BDB743843

--


Antigen:
CD148

Clone:
8A-1

Conjugate:
Brilliant Violet 510

Gene Alias:
Ptprj, R-PTP-J, BET, Byp, DEP-1, PTPbeta2, Ptpb2, R-PTP-eta, Scc-1, Scc1

Immunogen:
Mouse CD148 Transfected Cell Line

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Syrian Hamster

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG1

Img

BD Biosciences

BDB743845

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Antigen:
CD148

Clone:
8A-1

Conjugate:
Brilliant Violet 650

Gene Alias:
Ptprj, R-PTP-J, BET, Byp, DEP-1, PTPbeta2, Ptpb2, R-PTP-eta, Scc-1, Scc1

Immunogen:
Mouse CD148 Transfected Cell Line

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Syrian Hamster

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG1

Img

BD Biosciences

BDB743846

--


Antigen:
CD148

Clone:
8A-1

Conjugate:
Brilliant Violet 711

Gene Alias:
Ptprj, R-PTP-J, BET, Byp, DEP-1, PTPbeta2, Ptpb2, R-PTP-eta, Scc-1, Scc1

Immunogen:
Mouse CD148 Transfected Cell Line

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Syrian Hamster

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG1