BDB744205
CD212 Mouse anti-Human, Brilliant Violet 650, Clone: 2.4E6 (also known as 2-4E6), BD Optibuild™
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB744205-Each-of-1 | In Stock | ₹ 47,400.24 |
BDB744205 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,400.24
GST (18%): ₹ 8,532.043
Total Price: ₹ 55,932.283
Antigen
CD212
Clone
2.4E6 (also known as 2-4E6)
Conjugate
Brilliant Violet 650
Gene Alias
IL-12R beta 1, IL-12R-BETA1, IL-12 receptor β1, IMD30
Immunogen
PHA-activated Human PBMC
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification
Monoclonal
Concentration
0.2mg/mL
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Related Products
Description
- The 2.4E6 monoclonal antibody specifically binds to CD212, which is also known as the Interleukin-12 Receptor beta-1 chain (IL12RB1/IL-12RB1/IL-12Rβ1)
- CD212 serves as a subunit for the functional IL-12 Receptor (IL-12Rβ1-IL-12Rβ2) and IL-23 Receptor (IL-12Rβ1-IL-23R) complexes
- CD212 is expressed on T cells, B cells, or NK cells
- CD212 is a type I transmembrane glycoprotein that belongs to the hemopoietin receptor superfamily
- CD212 is responsible for binding to the IL-12 p40 subunit that is common to the heterodimeric IL-12 and IL-23 cytokines
- IL-12 and IL-23 are immunomodulatory cytokines produced mainly by antigen-presenting cells (APC) including monocytes and dendritic cells
- These cytokines have overlapping as well as distinct biological activities
- The antibody was conjugated to BD Horizon™ BV650 which is part of the BD Horizon Brilliant™ Violet family of dyes
- This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405nm and an acceptor dye with an Em Max at 650nm
- BD Horizon BV650 can be excited by the violet laser and detected in a filter used to detect APC-like dyes (eg, 660/20nm filter)
- Due to the excitation and emission characteristics of the acceptor dye, there will be spillover into the APC and Alexa Fluor™ 700 detectors
- However, the spillover can be corrected through compensation as with any other dye combination
- BV650 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an emission maximum at 650 nm
- Due to the excitation and emission characteristics of the acceptor dye, there will be spillover into the APC and Alexa Fluor™ 700 detectors
- BV650 will have moderate spillover into the BD Horizon™ BV711 detector.
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Antigen: CD212
Clone: 2.4E6 (also known as 2-4E6)
Conjugate: Brilliant Violet 650
Gene Alias: IL-12R beta 1, IL-12R-BETA1, IL-12 receptor β1, IMD30
Immunogen: PHA-activated Human PBMC
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD212
Clone:
2.4E6 (also known as 2-4E6)
Conjugate:
Brilliant Violet 650
Gene Alias:
IL-12R beta 1, IL-12R-BETA1, IL-12 receptor β1, IMD30
Immunogen:
PHA-activated Human PBMC
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: CD212
Clone: 2.4E6 (also known as 2-4E6)
Conjugate: Brilliant Violet 786
Gene Alias: IL-12R beta 1, IL-12R-BETA1, IL-12 receptor β1, IMD30
Immunogen: PHA-activated Human PBMC
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD212
Clone:
2.4E6 (also known as 2-4E6)
Conjugate:
Brilliant Violet 786
Gene Alias:
IL-12R beta 1, IL-12R-BETA1, IL-12 receptor β1, IMD30
Immunogen:
PHA-activated Human PBMC
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: CD212
Clone: 2.4E6 (also known as 2-4E6)
Conjugate: Brilliant Ultraviolet 395
Gene Alias: IL-12R beta 1, IL-12R-BETA1, IL-12 receptor β1, IMD30
Immunogen: PHA-activated Human PBMC
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
CD212
Clone:
2.4E6 (also known as 2-4E6)
Conjugate:
Brilliant Ultraviolet 395
Gene Alias:
IL-12R beta 1, IL-12R-BETA1, IL-12 receptor β1, IMD30
Immunogen:
PHA-activated Human PBMC
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: TIGIT
Clone: 1G9
Conjugate: Brilliant Violet 605
Gene Alias: Tigit, Vstm3, T cell immunoreceptor with Ig and ITIM domains
Immunogen: Mouse TIGIT Recombinant Protein
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG1 κ
Antigen:
TIGIT
Clone:
1G9
Conjugate:
Brilliant Violet 605
Gene Alias:
Tigit, Vstm3, T cell immunoreceptor with Ig and ITIM domains
Immunogen:
Mouse TIGIT Recombinant Protein
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG1 κ