BDB744539

CD102 Mouse anti-Human, Brilliant Violet 650, Clone: CBR-IC2/2, BD Optibuild™

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB744539-Each-of-1 In Stock ₹ 47,400.24

BDB744539 - Each of 1

₹ 47,400.24

In Stock

Quantity

1

Base Price: ₹ 47,400.24

GST (18%): ₹ 8,532.043

Total Price: ₹ 55,932.283

Antigen

CD102

Clone

CBR-IC2/2

Conjugate

Brilliant Violet 650

Gene Alias

ICAM2, ICAM-2, Intercellular adhesion molecule 2

Immunogen

Human ICAM-2 Transfected Cell Line

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification

Monoclonal

Concentration

0.2mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG2a κ

Related Products

Img

BD Biosciences

BDB744537

--

Img

BD Biosciences

BDB744538

--

Img

BD Biosciences

BDB744536

--

Img

BD Biosciences

BDB744541

--

Img

BD Biosciences

BDB744311

--

Img

BD Biosciences

BDB744465

--

Img

BD Biosciences

BDB744140

--

Img

BD Biosciences

BDB744198

--

Description

  • The CBR-IC2/2 monoclonal antibody specifically binds to CD102 which is also known as, intercellular adhesion molecule-2 (ICAM-2/ICAM2)
  • CD102 is a type I transmembrane glycoprotein, member of the immunoglobulin supergene family, with an approximate molecular weight of 55-65 kDa
  • Its extracellular domain consists of two C2-type immunoglobulin-like subunits
  • The transmembrane region is 26 residues in size and the intracellular region also has 26 residues
  • CD102 is expressed on vascular endothelial cells, lymphocytes, monocytes, eosinophils, and platelets, but not on resting neutrophils
  • It is a ligand for the leukocyte integrin CD11a/CD18, or leukocyte function-associated antigen-1 (LFA-1), and there are reports of CD102 binding to leukocyte integrin CD11b/CD18 (Mac-1)
  • Antibody CBR-IC2/2 blocks the binding of CD102 to leukocyte integrin CD11a/CD18
  • CD102 plays an important role in lymphocyte recirculation and in providing costimulatory signals in the immune response
  • The antibody was conjugated to BD Horizon™ BV650 which is part of the BD Horizon Brilliant™ Violet family of dyes
  • This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405nm and an acceptor dye with an Em Max at 650nm
  • BD Horizon BV650 can be excited by the violet laser and detected in a filter used to detect APC-like dyes (eg, 660/20nm filter)
  • Due to the excitation and emission characteristics of the acceptor dye, there will be spillover into the APC and Alexa Fluor™ 700 detectors
  • However, the spillover can be corrected through compensation as with any other dye combination
  • BV650 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an emission maximum at 650 nm
  • Due to the excitation and emission characteristics of the acceptor dye, there will be spillover into the APC and Alexa Fluor™ 700 detectors
  • BV650 will have moderate spillover into the BD Horizon™ BV711 detector.

Compare Similar Items

Show Difference

Img

BD Biosciences

BDB744539

--


Antigen:
CD102

Clone:
CBR-IC2/2

Conjugate:
Brilliant Violet 650

Gene Alias:
ICAM2, ICAM-2, Intercellular adhesion molecule 2

Immunogen:
Human ICAM-2 Transfected Cell Line

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG2a κ

Img

BD Biosciences

BDB744541

--


Antigen:
CD102

Clone:
CBR-IC2/2

Conjugate:
Brilliant Violet 786

Gene Alias:
ICAM2, ICAM-2, Intercellular adhesion molecule 2

Immunogen:
Human ICAM-2 Transfected Cell Line

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG2a κ

Img

BD Biosciences

BDB744544

--


Antigen:
CD279

Clone:
J43

Conjugate:
Brilliant Violet 510

Gene Alias:
PD-1

Immunogen:
Syrian Hamster kidney cell line BKH transfected with Pdcd1 cDNA

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Armenian Hamster

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2 κ

Img

BD Biosciences

BDB744546

--


Antigen:
CD279

Clone:
J43

Conjugate:
Brilliant Violet 650

Gene Alias:
PD-1

Immunogen:
Syrian Hamster kidney cell line BKH transfected with Pdcd1 cDNA

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Armenian Hamster

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2 κ