ENMP390

TNF alpha Monoclonal Antibody (4F4), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 ENMP390-Each-of-1 In Stock ₹ 42,737.22

ENMP390 - Each of 1

₹ 42,737.22

In Stock

Quantity

1

Base Price: ₹ 42,737.22

GST (18%): ₹ 7,692.70

Total Price: ₹ 50,429.92

Antigen

TNF alpha

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

P23563

Gene Symbols

Tnf

Immunogen

Recombinant porcine TNF alpha (Baculovirus-derived)

Quantity

500 μg

Primary or Secondary

Primary

Target Species

Porcine

Product Type

Antibody

Isotype

IgG1

Applications

ELISA, Western Blot

Clone

4F4

Conjugate

Unconjugated

Gene

Tnf

Gene Alias

APC1 protein; Cachectin; C-domain 1; C-domain 2; cTNF; DADB-70P7.1; DIF; ICD1; ICD2; Intracellular domain 1; Intracellular domain 2; N-terminal fragment; NTF; RATTNF; Tnf; TNF alpha; TNF superfamily; TNF a; TNF, macrophage-derived; TNF, monocyte-derived; TNFA; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; TNFSF2; TNFa; TNLG1F; Tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor alpha (cachetin); tumor necrosis factor alpha precursor; tumor necrosis factor ligand 1F; tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form; tumor necrosis factor-alpha; tumor necrosis factor-alpha precursor; tumor-necrosis factor; tumour necrosis factor

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

397086

Content And Storage

-20°C

Form

Liquid

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Description

  • MP390 detects natural and recombinant TNF alpha, with a predicted molecular weight of approximately 25 kDa
  • This antibody will not cross-react with human or mouse TNFa, mouse TNFb, or porcine TNFb
  • This is a carrier-free low endotoxin formulation, <1.0 EU/mg
  • This product can be used as a coating antibody in a sandwich ELISA (100 μg/well) in combination with biotin-labeled TNFa monoclonal antibody (Product # M302B, 0.1-0.65 μg/mL)
  • For Western blot, this antibody has been successfully used in conjunction with 0.02 μg/mL Biotin-conjugated Goat-anti-Mouse IgG (Product # 31800), 0.05 μg/mL HRP-conjugated Streptavidin (Product # N100), and recombinant Porcine TNFa (Product # RPTNFAI), followed by visualization using SuperSignal™ West Pico Chemiluminescent Substrate (Product # 34080)
  • This product has been tested for endotoxins by limulus amoebocyte lysate (LAL) assay and contains an endotoxin concentration of less than or equal to 10 endotoxin units per milligram (EU/mg)
  • TNF alpha is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily
  • This cytokine is mainly secreted by macrophage and bind to its receptors, TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR
  • TNF alpha is involved in the regulation of immune cells, cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation
  • TNF alpha exists as a multimer of two, three, or five noncovalently linked units, but shows a single 17 kDa band following SDS-PAGE under non-reducing conditions
  • Knockout studies in mice also suggested the neuroprotective function of TNF alpha, and has been observed to causes tumor necrosis when injected into tumor-bearing mice
  • Other functions of TNF-alpha include its role in the immune response to bacterial, viral, parasitic and certain fungal infections, as well as its role in the necrosis of specific tumors
  • TNF alpha causes cytolysis or cytostasis of certain transformed cells, being synergistic with interferon-gamma in its cytotoxicity
  • This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer.

Compare Similar Items

Show Difference

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Thermo Scientific

ENMP390

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Antigen:
TNF alpha

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P23563

Gene Symbols:
Tnf

Immunogen:
Recombinant porcine TNF alpha (Baculovirus-derived)

Quantity:
500 μg

Primary or Secondary:
Primary

Target Species:
Porcine

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Western Blot

Clone:
4F4

Conjugate:
Unconjugated

Gene:
Tnf

Gene Alias:
APC1 protein; Cachectin; C-domain 1; C-domain 2; cTNF; DADB-70P7.1; DIF; ICD1; ICD2; Intracellular domain 1; Intracellular domain 2; N-terminal fragment; NTF; RATTNF; Tnf; TNF alpha; TNF superfamily; TNF a; TNF, macrophage-derived; TNF, monocyte-derived; TNFA; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; TNFSF2; TNFa; TNLG1F; Tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor alpha (cachetin); tumor necrosis factor alpha precursor; tumor necrosis factor ligand 1F; tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form; tumor necrosis factor-alpha; tumor necrosis factor-alpha precursor; tumor-necrosis factor; tumour necrosis factor

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
397086

Content And Storage:
-20°C

Form:
Liquid

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Thermo Scientific

ENMP700

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Antigen:
IFN gamma

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P17803

Gene Symbols:
IFNG

Immunogen:
Recombinant porcine IFN gamma

Quantity:
500 μg

Primary or Secondary:
Primary

Target Species:
Porcine

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
ELISA, Western Blot

Clone:
P2F6

Conjugate:
Unconjugated

Gene:
IFNG

Gene Alias:
BoIFNG; cytokine; EGK_03901; gamma interferon; gamma interferon precursor; gamma-interferon; gamma-interferon precursor (AA -23 to 143); H-IFN-g; IFG; IFI; IFN gamma; IFN ?; Ifng; IFN-g; IFNG2; IFN-gamma; IFN-gamma precursor; IFN-y; IFN?; Immune interferon; interferon gamma; interferon gamma precursor; interferon gamma type 2; Interferon y; Interferon ?; interferon, gamma; interferon-gama; interferon-gamma; Interferon-gamma level; interferon-gamma precursor; Interferon?; M-IFN-g; R-IFN-g

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
396991

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

ENMP701B

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Antigen:
IFN gamma

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 4% BSA and proprietary preservative

Gene Accession No.:
P17803

Gene Symbols:
IFNG

Immunogen:
Recombinant porcine IFN gamma

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Porcine

Product Type:
Antibody

Isotype:
IgG2a κ

Applications:
ELISA, Western Blot

Clone:
P2C11

Conjugate:
Biotin

Gene:
IFNG

Gene Alias:
BoIFNG; cytokine; EGK_03901; gamma interferon; gamma interferon precursor; gamma-interferon; gamma-interferon precursor (AA -23 to 143); H-IFN-g; IFG; IFI; IFN gamma; IFN ?; Ifng; IFN-g; IFNG2; IFN-gamma; IFN-gamma precursor; IFN-y; IFN?; Immune interferon; interferon gamma; interferon gamma precursor; interferon gamma type 2; Interferon y; Interferon ?; interferon, gamma; interferon-gama; interferon-gamma; Interferon-gamma level; interferon-gamma precursor; Interferon?; M-IFN-g; R-IFN-g

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
396991

Content And Storage:
-20°C

Form:
Liquid

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ENMTNFAI

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Antigen:
TNF alpha

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 10% trehalose and no preservative

Gene Accession No.:
P01375

Gene Symbols:
Tnf

Immunogen:
Recombinant human TNF alpha from Pichia pastoris.

Quantity:
500 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Western Blot

Clone:
E10043

Conjugate:
Unconjugated

Gene:
Tnf

Gene Alias:
APC1 protein; Cachectin; C-domain 1; C-domain 2; cTNF; DADB-70P7.1; DIF; ICD1; ICD2; Intracellular domain 1; Intracellular domain 2; N-terminal fragment; NTF; RATTNF; Tnf; TNF alpha; TNF superfamily; TNF a; TNF, macrophage-derived; TNF, monocyte-derived; TNFA; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; TNFSF2; TNFa; TNLG1F; Tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor alpha (cachetin); tumor necrosis factor alpha precursor; tumor necrosis factor ligand 1F; tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form; tumor necrosis factor-alpha; tumor necrosis factor-alpha precursor; tumor-necrosis factor; tumour necrosis factor

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
7124

Content And Storage:
-20°C

Form:
Lyophilized