FEMA549761

Phospho-c-Myc (Thr58, Ser62) Recombinant Rabbit Monoclonal Antibody (4E9), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA549761-Each-of-1 In Stock ₹ 35,764.08

FEMA549761 - Each of 1

₹ 35,764.08

In Stock

Quantity

1

Base Price: ₹ 35,764.08

GST (18%): ₹ 6,437.534

Total Price: ₹ 42,201.614

Antigen

Phospho-c-Myc (Thr58, Ser62)

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.

P01106

Gene Symbols

MYC

Immunogen

A synthesized peptide derived from human Phospho-MYC (T58+S62)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Western Blot

Clone

4E9

Conjugate

Unconjugated

Gene

MYC

Gene Alias

AU016757, Avian myelocytomatosis viral (v-myc) oncogene homolog, avian myelocytomatosis viral oncogene homolog, bHLHe39, c Myc, class E basic helix-loop-helix protein 39, cmyc, c-Myc, c-myc epitope tag, c-myc proto-oncogene, mMyc, MRTL, Myc, Myc protein, Myc proto-oncogene protein, MYC proto-oncogene, bHLH transcription factor, Myc2, MYCC, myc-related translation/localization regulatory factor, myelocytomatosis oncogene, myelocytomatosis viral oncogene homolog, Niard, Nird, Proto-oncogene c-Myc, RNCMYC, Transcription factor p64, v-myc avian myelocytomatosis viral oncogene homolog, v-myc myelocytomatosis viral oncogene homolog, v-myc myelocytomatosis viral oncogene-like protein

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

4609

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG

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Description

  • The c-Myc protein is a 62 kDa transcription factor that is encoded by the c-Myc gene on human chromosome 8q24
  • c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression
  • The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin dependent kinase, ERK2 and C-Jun N terminal Kinase (JNK) in cell proliferation and cell cycle regulation
  • Studies have shown that c-Myc is essential for vasculogenesis and angiogenesis in tumor development, which distributes blood throughout the cells
  • The c-myc oncogene (p62 c-myc) is involved in the control of normal cellular proliferation and differentiation, and the deregulated expression of c-Myc induces apoptosis in different cell types
  • Antibodies against c-myc epitopes recognize overexpressed proteins containing Myc epitope tag fused to either amino- or carboxy-termini of targeted proteins
  • c-Myc-, N-Myc- and L-Myc-encoded proteins function in cell proliferation, differentiation and neoplastic disease
  • Amplification of the c-Myc gene has been found in several types of human tumors including lung, breast and colon carcinomas, while the N-Myc gene has been found amplified in neuroblastomas
  • Translocation of the c-myc locus on chromosome 8 to the immunoglobulin loci on chromosome 14 (heavy chain); 2 (delta light chain); or 22 (light chain) is described in Burkitts lymphoma and other B-cell lymphoproliferative conditions
  • An aberrant expression of the c-myc gene occurs in tumors of different origins such as colorectal, gastric, gallbladder, hepatic, mammary, ovarian, endometrial, head and neck, pulmonary, prostatic, thyroidal, oral, ocular, nasopharyngeal, endocrine, as well as hematopoietic neoplasms.

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FEMA549761

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Antigen:
Phospho-c-Myc (Thr58, Ser62)

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P01106

Gene Symbols:
MYC

Immunogen:
A synthesized peptide derived from human Phospho-MYC (T58+S62)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Western Blot

Clone:
4E9

Conjugate:
Unconjugated

Gene:
MYC

Gene Alias:
AU016757, Avian myelocytomatosis viral (v-myc) oncogene homolog, avian myelocytomatosis viral oncogene homolog, bHLHe39, c Myc, class E basic helix-loop-helix protein 39, cmyc, c-Myc, c-myc epitope tag, c-myc proto-oncogene, mMyc, MRTL, Myc, Myc protein, Myc proto-oncogene protein, MYC proto-oncogene, bHLH transcription factor, Myc2, MYCC, myc-related translation/localization regulatory factor, myelocytomatosis oncogene, myelocytomatosis viral oncogene homolog, Niard, Nird, Proto-oncogene c-Myc, RNCMYC, Transcription factor p64, v-myc avian myelocytomatosis viral oncogene homolog, v-myc myelocytomatosis viral oncogene homolog, v-myc myelocytomatosis viral oncogene-like protein

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4609

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

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FEMA549763

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Antigen:
Phospho-STAT5 alpha (Tyr694)

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P42229

Gene Symbols:
STAT5A

Immunogen:
A synthesized peptide derived from human Phospho-STAT5A (Y694)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Clone:
3F1

Conjugate:
Unconjugated

Gene:
STAT5A

Gene Alias:
AA959963, mammary gland factor, mammary gland factor STAT5A, mammary gland factor, transcription factor, Mgf, Mpf, signal transducer and activator of transcription 5, signal transducer and activator of transcription 5a, signal transducer and activator of transcription factor 5A, STAT, STAT5, STAT5A, STAT5A, Mammary Gland Factor, STAT5A/MGF, STAT5B, STATA5

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6776

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

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FEMA549765

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Antigen:
Phospho-IkB alpha (Ser32)

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P25963

Gene Symbols:
NFKBIA

Immunogen:
A synthesized peptide derived from human Phospho-NFKBIA (S32)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Western Blot

Clone:
2D6

Conjugate:
Unconjugated

Gene:
NFKBIA

Gene Alias:
AI462015, ECI-6, ECI-6/IKBA, I kappa B-alpha, I(Kappa)B(alpha), I79_018146, IkappaB alpha, IkappaBalpha, I-kappaBalpha, I-kappa-B-alpha, Ikba, IKBalpha, IKB-alpha, Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells alpha, Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells, alpha, MAD3, MAD-3, Major histocompatibility complex enhancer-binding protein MAD3, NF kappa B inhibitor alpha, NF-kappaB inhibitor alpha, NF-kappa-B inhibitor alpha, NFKB inhibitor alpha, NFKBI, Nfkbia, nuclear factor of kappa light chain gene enhancer in B-cells, nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha, nuclear factor of kappa light polyp gene enhancer in B-cell 1, nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha, Rel-associated pp40, REL-associated protein pp40, RL/IF-1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4792

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

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Antigen:
Phospho-Estrogen Receptor alpha (Ser118)

Classification:
Recombinant Monoclonal

Concentration:
2 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P03372

Gene Symbols:
ESR1

Immunogen:
A synthesized peptide derived from human Phospho-ESR1 (S118)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin)

Clone:
4H1

Conjugate:
Unconjugated

Gene:
ESR1

Gene Alias:
DKFZp686N23123, ER, Er alpha, ER36, ERa, ERalpha, ER-alpha, ERalpha protein, ESR, esr 1, Esr1, esr-1, ESRA, Estr, Estra, Estradiol receptor, estrogen nuclear receptor alpha, Estrogen receptor, estrogen receptor 1, estrogen receptor 1 (alpha), estrogen receptor alpha, estrogen receptor alpha c-terminus splice variant 1-2, estrogen receptor alpha E1-E2-1-2, estrogen receptor alpha E1-N2-E2-1-2, estrogen receptor alpha splice variant, CTERP-1, estrogen receptor alpha splice variant, ERalphaDup5, estrogen receptor alpha splice variant, ERalphai45a, estrogen receptor alpha splice variant, ERalphai45bL, estrogen receptor alpha splice variant, ERalphai45bS, estrogen receptor alpha splice variant, ERalphai45c, estrogen receptor alpha splice variant, ERalphai56, estrogen receptor alpha splice variant, ERalphai67, estrogen receptor alpha variant delta 4, estrogen receptor protein, estrogen receptor, alpha, ESTRR, hER-alpha36, I79_001166, Nr3a1, nuclear receptor, nuclear receptor subfamily 3 group A member 1, RNESTROR, RP1-130E4.1, unnamed protein product

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2099

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG