FEMA549765
Phospho-IkB alpha (Ser32) Recombinant Rabbit Monoclonal Antibody (2D6), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA549765-Each-of-1 | In Stock | ₹ 35,764.08 |
FEMA549765 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 35,764.08
GST (18%): ₹ 6,437.534
Total Price: ₹ 42,201.614
Antigen
Phospho-IkB alpha (Ser32)
Classification
Recombinant Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.
P25963
Gene Symbols
NFKBIA
Immunogen
A synthesized peptide derived from human Phospho-NFKBIA (S32)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
ELISA, Immunocytochemistry, Western Blot
Clone
2D6
Conjugate
Unconjugated
Gene
NFKBIA
Gene Alias
AI462015, ECI-6, ECI-6/IKBA, I kappa B-alpha, I(Kappa)B(alpha), I79_018146, IkappaB alpha, IkappaBalpha, I-kappaBalpha, I-kappa-B-alpha, Ikba, IKBalpha, IKB-alpha, Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells alpha, Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells, alpha, MAD3, MAD-3, Major histocompatibility complex enhancer-binding protein MAD3, NF kappa B inhibitor alpha, NF-kappaB inhibitor alpha, NF-kappa-B inhibitor alpha, NFKB inhibitor alpha, NFKBI, Nfkbia, nuclear factor of kappa light chain gene enhancer in B-cells, nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha, nuclear factor of kappa light polyp gene enhancer in B-cell 1, nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha, Rel-associated pp40, REL-associated protein pp40, RL/IF-1
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
4792
Content And Storage
-20°C or -80°C if preferred
Isotype
IgG
Related Products
Description
- IkB-alpha is a 40 kDa protein that functions to inhibit NF- kappaB activity
- The inhibition occurs via protein-protein interaction between I kappaB proteins and NF- kappaB dimers in the cytosol
- The interaction of I kappa B-alpha with NF- kappaB masks the nuclear localization sequence of NF- kappaB, preventing NF- kappaB translocation to the nucleus
- A variety of stimuli can activate gene expression by liberating NF- kappaB through the degradation of I kappaB alpha
- These stimuli include the proinflammatory cytokines TNF- alpha and IL-1 beta, chemokines, PMA, growth factors, LPS, UV irradiation, viral infection, as well as various chemical and physical stresses
- In humans, the gene is located on the q arm of chromosome 14
- Activation of NFkB requires that IkB be phosphorylated on specific serine residues, which results in targeted degradation of IkB
- IkB kinase alpha (IKK alpha), previously designated CHUK, interacts with IkB-alpha and specifically phosphorylates IkB-alpha on the sites that trigger its degradation Serines 32 and 36
- IKK alpha appears to be critical for NFkB activation in response to proinflammatory cytokines
- Phosphorylation of IkB by IKK alpha is stimulated by the NFkB inducing kinase (NIK), which itself is a central regulator for NFkB activation in response to TNF and IL-1
- The functional IKK complex contains three subunits, IKK alpha, IKK beta and IKK gamma, and each appear to make essential contributions to IkB phosphorylation.
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Antigen: Phospho-IkB alpha (Ser32)
Classification: Recombinant Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.: P25963
Gene Symbols: NFKBIA
Immunogen: A synthesized peptide derived from human Phospho-NFKBIA (S32)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Immunocytochemistry, Western Blot
Clone: 2D6
Conjugate: Unconjugated
Gene: NFKBIA
Gene Alias: AI462015, ECI-6, ECI-6/IKBA, I kappa B-alpha, I(Kappa)B(alpha), I79_018146, IkappaB alpha, IkappaBalpha, I-kappaBalpha, I-kappa-B-alpha, Ikba, IKBalpha, IKB-alpha, Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells alpha, Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells, alpha, MAD3, MAD-3, Major histocompatibility complex enhancer-binding protein MAD3, NF kappa B inhibitor alpha, NF-kappaB inhibitor alpha, NF-kappa-B inhibitor alpha, NFKB inhibitor alpha, NFKBI, Nfkbia, nuclear factor of kappa light chain gene enhancer in B-cells, nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha, nuclear factor of kappa light polyp gene enhancer in B-cell 1, nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha, Rel-associated pp40, REL-associated protein pp40, RL/IF-1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4792
Content And Storage: -20°C or -80°C if preferred
Isotype: IgG
Antigen:
Phospho-IkB alpha (Ser32)
Classification:
Recombinant Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.:
P25963
Gene Symbols:
NFKBIA
Immunogen:
A synthesized peptide derived from human Phospho-NFKBIA (S32)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Immunocytochemistry, Western Blot
Clone:
2D6
Conjugate:
Unconjugated
Gene:
NFKBIA
Gene Alias:
AI462015, ECI-6, ECI-6/IKBA, I kappa B-alpha, I(Kappa)B(alpha), I79_018146, IkappaB alpha, IkappaBalpha, I-kappaBalpha, I-kappa-B-alpha, Ikba, IKBalpha, IKB-alpha, Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells alpha, Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells, alpha, MAD3, MAD-3, Major histocompatibility complex enhancer-binding protein MAD3, NF kappa B inhibitor alpha, NF-kappaB inhibitor alpha, NF-kappa-B inhibitor alpha, NFKB inhibitor alpha, NFKBI, Nfkbia, nuclear factor of kappa light chain gene enhancer in B-cells, nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha, nuclear factor of kappa light polyp gene enhancer in B-cell 1, nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha, Rel-associated pp40, REL-associated protein pp40, RL/IF-1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4792
Content And Storage:
-20°C or -80°C if preferred
Isotype:
IgG
Antigen: Phospho-Estrogen Receptor alpha (Ser118)
Classification: Recombinant Monoclonal
Concentration: 2 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.: P03372
Gene Symbols: ESR1
Immunogen: A synthesized peptide derived from human Phospho-ESR1 (S118)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Immunohistochemistry (Paraffin)
Clone: 4H1
Conjugate: Unconjugated
Gene: ESR1
Gene Alias: DKFZp686N23123, ER, Er alpha, ER36, ERa, ERalpha, ER-alpha, ERalpha protein, ESR, esr 1, Esr1, esr-1, ESRA, Estr, Estra, Estradiol receptor, estrogen nuclear receptor alpha, Estrogen receptor, estrogen receptor 1, estrogen receptor 1 (alpha), estrogen receptor alpha, estrogen receptor alpha c-terminus splice variant 1-2, estrogen receptor alpha E1-E2-1-2, estrogen receptor alpha E1-N2-E2-1-2, estrogen receptor alpha splice variant, CTERP-1, estrogen receptor alpha splice variant, ERalphaDup5, estrogen receptor alpha splice variant, ERalphai45a, estrogen receptor alpha splice variant, ERalphai45bL, estrogen receptor alpha splice variant, ERalphai45bS, estrogen receptor alpha splice variant, ERalphai45c, estrogen receptor alpha splice variant, ERalphai56, estrogen receptor alpha splice variant, ERalphai67, estrogen receptor alpha variant delta 4, estrogen receptor protein, estrogen receptor, alpha, ESTRR, hER-alpha36, I79_001166, Nr3a1, nuclear receptor, nuclear receptor subfamily 3 group A member 1, RNESTROR, RP1-130E4.1, unnamed protein product
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 2099
Content And Storage: -20°C or -80°C if preferred
Isotype: IgG
Antigen:
Phospho-Estrogen Receptor alpha (Ser118)
Classification:
Recombinant Monoclonal
Concentration:
2 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.:
P03372
Gene Symbols:
ESR1
Immunogen:
A synthesized peptide derived from human Phospho-ESR1 (S118)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Immunohistochemistry (Paraffin)
Clone:
4H1
Conjugate:
Unconjugated
Gene:
ESR1
Gene Alias:
DKFZp686N23123, ER, Er alpha, ER36, ERa, ERalpha, ER-alpha, ERalpha protein, ESR, esr 1, Esr1, esr-1, ESRA, Estr, Estra, Estradiol receptor, estrogen nuclear receptor alpha, Estrogen receptor, estrogen receptor 1, estrogen receptor 1 (alpha), estrogen receptor alpha, estrogen receptor alpha c-terminus splice variant 1-2, estrogen receptor alpha E1-E2-1-2, estrogen receptor alpha E1-N2-E2-1-2, estrogen receptor alpha splice variant, CTERP-1, estrogen receptor alpha splice variant, ERalphaDup5, estrogen receptor alpha splice variant, ERalphai45a, estrogen receptor alpha splice variant, ERalphai45bL, estrogen receptor alpha splice variant, ERalphai45bS, estrogen receptor alpha splice variant, ERalphai45c, estrogen receptor alpha splice variant, ERalphai56, estrogen receptor alpha splice variant, ERalphai67, estrogen receptor alpha variant delta 4, estrogen receptor protein, estrogen receptor, alpha, ESTRR, hER-alpha36, I79_001166, Nr3a1, nuclear receptor, nuclear receptor subfamily 3 group A member 1, RNESTROR, RP1-130E4.1, unnamed protein product
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2099
Content And Storage:
-20°C or -80°C if preferred
Isotype:
IgG
Antigen: Phospho-Tau (Thr231)
Classification: Recombinant Monoclonal
Concentration: 0.4 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.: P10636
Gene Symbols: MAPT
Immunogen: A synthesized peptide derived from human Phospho-MAPT (T231)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Western Blot
Clone: 1G9
Conjugate: Unconjugated
Gene: MAPT
Gene Alias: AI413597, AW045860, DDPAC, FLJ31424, FTDP17, FTDP-17, G protein beta1/gamma2 subunit-interacting factor 1, map tau, Mapt, MAPTL, MGC138549, microtubule associated protein tau, microtubule-associated protein tau, microtubule-associated protein tau, isoform 4, microtubules, MSTD, Mtapt, MTBT1, MTBT2, Neurofibrillary tangle protein, neurofibrillary tangles, Neuronal Marker, paired helical filament-tau, PHFtau, PHF-tau, PPND, PPP1R103, protein phosphatase 1, regulatory subunit 103, pTau, RNPTAU, Tau, Tau microtubule-associated protein, tau protein, Tau-4, Tau5, Unknown (protein for MGC:134287)
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4137
Content And Storage: -20°C or -80°C if preferred
Isotype: IgG
Antigen:
Phospho-Tau (Thr231)
Classification:
Recombinant Monoclonal
Concentration:
0.4 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.:
P10636
Gene Symbols:
MAPT
Immunogen:
A synthesized peptide derived from human Phospho-MAPT (T231)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Western Blot
Clone:
1G9
Conjugate:
Unconjugated
Gene:
MAPT
Gene Alias:
AI413597, AW045860, DDPAC, FLJ31424, FTDP17, FTDP-17, G protein beta1/gamma2 subunit-interacting factor 1, map tau, Mapt, MAPTL, MGC138549, microtubule associated protein tau, microtubule-associated protein tau, microtubule-associated protein tau, isoform 4, microtubules, MSTD, Mtapt, MTBT1, MTBT2, Neurofibrillary tangle protein, neurofibrillary tangles, Neuronal Marker, paired helical filament-tau, PHFtau, PHF-tau, PPND, PPP1R103, protein phosphatase 1, regulatory subunit 103, pTau, RNPTAU, Tau, Tau microtubule-associated protein, tau protein, Tau-4, Tau5, Unknown (protein for MGC:134287)
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4137
Content And Storage:
-20°C or -80°C if preferred
Isotype:
IgG
Antigen: Phospho-MSK1 (Ser376)
Classification: Recombinant Monoclonal
Concentration: 0.36 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.: O75582
Gene Symbols: Rps6ka5
Immunogen: A synthesized peptide derived from human Phospho-RPS6KA5 (S376)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Immunohistochemistry (Paraffin)
Clone: 2F3
Conjugate: Unconjugated
Gene: Rps6ka5
Gene Alias: 3110005L17Rik, 6330404E13Rik, 90 kDa ribosomal protein S6 kinase 5, AI854034, kinase MSK1, KS6A5, mitogen and stress-activated protein kinase 1, Msk1, MSPK1, Nuclear mitogen- and stress-activated protein kinase 1, ribosomal protein S6 kinase A5, ribosomal protein S6 kinase alpha-5, ribosomal protein S6 kinase, 90kDa, polypeptide 5, ribosomal protein S6 kinase, polypeptide 5, RLPK, RLSK, Rps6ka5, RSKL, RSK-like protein kinase, S6K-alpha-5
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 9252
Content And Storage: -20°C or -80°C if preferred
Isotype: IgG
Antigen:
Phospho-MSK1 (Ser376)
Classification:
Recombinant Monoclonal
Concentration:
0.36 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.:
O75582
Gene Symbols:
Rps6ka5
Immunogen:
A synthesized peptide derived from human Phospho-RPS6KA5 (S376)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Immunohistochemistry (Paraffin)
Clone:
2F3
Conjugate:
Unconjugated
Gene:
Rps6ka5
Gene Alias:
3110005L17Rik, 6330404E13Rik, 90 kDa ribosomal protein S6 kinase 5, AI854034, kinase MSK1, KS6A5, mitogen and stress-activated protein kinase 1, Msk1, MSPK1, Nuclear mitogen- and stress-activated protein kinase 1, ribosomal protein S6 kinase A5, ribosomal protein S6 kinase alpha-5, ribosomal protein S6 kinase, 90kDa, polypeptide 5, ribosomal protein S6 kinase, polypeptide 5, RLPK, RLSK, Rps6ka5, RSKL, RSK-like protein kinase, S6K-alpha-5
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
9252
Content And Storage:
-20°C or -80°C if preferred
Isotype:
IgG