FEMA549791
IkB alpha Recombinant Rabbit Monoclonal Antibody (1E9), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA549791-Each-of-1 | In Stock | ₹ 35,764.08 |
FEMA549791 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 35,764.08
GST (18%): ₹ 6,437.534
Total Price: ₹ 42,201.614
Antigen
IkB alpha
Classification
Recombinant Monoclonal
Concentration
0.25 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.
P25963
Gene Symbols
NFKBIA
Immunogen
A synthesized peptide derived from human NFKBIA
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone
1E9
Conjugate
Unconjugated
Gene
NFKBIA
Gene Alias
AI462015, ECI-6, ECI-6/IKBA, I kappa B-alpha, I(Kappa)B(alpha), I79_018146, IkappaB alpha, IkappaBalpha, I-kappaBalpha, I-kappa-B-alpha, Ikba, IKBalpha, IKB-alpha, Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells alpha, Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells, alpha, MAD3, MAD-3, Major histocompatibility complex enhancer-binding protein MAD3, NF kappa B inhibitor alpha, NF-kappaB inhibitor alpha, NF-kappa-B inhibitor alpha, NFKB inhibitor alpha, NFKBI, Nfkbia, nuclear factor of kappa light chain gene enhancer in B-cells, nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha, nuclear factor of kappa light polyp gene enhancer in B-cell 1, nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha, Rel-associated pp40, REL-associated protein pp40, RL/IF-1
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
4792
Content And Storage
-20°C or -80°C if preferred
Isotype
IgG
Related Products
Description
- IkB-alpha is a 40 kDa protein that functions to inhibit NF- kappaB activity
- The inhibition occurs via protein-protein interaction between I kappaB proteins and NF- kappaB dimers in the cytosol
- The interaction of I kappa B-alpha with NF- kappaB masks the nuclear localization sequence of NF- kappaB, preventing NF- kappaB translocation to the nucleus
- A variety of stimuli can activate gene expression by liberating NF- kappaB through the degradation of I kappaB alpha
- These stimuli include the proinflammatory cytokines TNF- alpha and IL-1 beta, chemokines, PMA, growth factors, LPS, UV irradiation, viral infection, as well as various chemical and physical stresses
- In humans, the gene is located on the q arm of chromosome 14
- Activation of NFkB requires that IkB be phosphorylated on specific serine residues, which results in targeted degradation of IkB
- IkB kinase alpha (IKK alpha), previously designated CHUK, interacts with IkB-alpha and specifically phosphorylates IkB-alpha on the sites that trigger its degradation Serines 32 and 36
- IKK alpha appears to be critical for NFkB activation in response to proinflammatory cytokines
- Phosphorylation of IkB by IKK alpha is stimulated by the NFkB inducing kinase (NIK), which itself is a central regulator for NFkB activation in response to TNF and IL-1
- The functional IKK complex contains three subunits, IKK alpha, IKK beta and IKK gamma, and each appear to make essential contributions to IkB phosphorylation.
Compare Similar Items
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Antigen: IkB alpha
Classification: Recombinant Monoclonal
Concentration: 0.25 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.: P25963
Gene Symbols: NFKBIA
Immunogen: A synthesized peptide derived from human NFKBIA
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: 1E9
Conjugate: Unconjugated
Gene: NFKBIA
Gene Alias: AI462015, ECI-6, ECI-6/IKBA, I kappa B-alpha, I(Kappa)B(alpha), I79_018146, IkappaB alpha, IkappaBalpha, I-kappaBalpha, I-kappa-B-alpha, Ikba, IKBalpha, IKB-alpha, Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells alpha, Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells, alpha, MAD3, MAD-3, Major histocompatibility complex enhancer-binding protein MAD3, NF kappa B inhibitor alpha, NF-kappaB inhibitor alpha, NF-kappa-B inhibitor alpha, NFKB inhibitor alpha, NFKBI, Nfkbia, nuclear factor of kappa light chain gene enhancer in B-cells, nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha, nuclear factor of kappa light polyp gene enhancer in B-cell 1, nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha, Rel-associated pp40, REL-associated protein pp40, RL/IF-1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4792
Content And Storage: -20°C or -80°C if preferred
Isotype: IgG
Antigen:
IkB alpha
Classification:
Recombinant Monoclonal
Concentration:
0.25 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.:
P25963
Gene Symbols:
NFKBIA
Immunogen:
A synthesized peptide derived from human NFKBIA
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
1E9
Conjugate:
Unconjugated
Gene:
NFKBIA
Gene Alias:
AI462015, ECI-6, ECI-6/IKBA, I kappa B-alpha, I(Kappa)B(alpha), I79_018146, IkappaB alpha, IkappaBalpha, I-kappaBalpha, I-kappa-B-alpha, Ikba, IKBalpha, IKB-alpha, Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells alpha, Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells, alpha, MAD3, MAD-3, Major histocompatibility complex enhancer-binding protein MAD3, NF kappa B inhibitor alpha, NF-kappaB inhibitor alpha, NF-kappa-B inhibitor alpha, NFKB inhibitor alpha, NFKBI, Nfkbia, nuclear factor of kappa light chain gene enhancer in B-cells, nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha, nuclear factor of kappa light polyp gene enhancer in B-cell 1, nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha, Rel-associated pp40, REL-associated protein pp40, RL/IF-1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4792
Content And Storage:
-20°C or -80°C if preferred
Isotype:
IgG
Antigen: CETP
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.: P11597
Gene Symbols: CETP
Immunogen: A synthesized peptide derived from human CETP
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Immunohistochemistry (Paraffin)
Clone: 2F1
Conjugate: Unconjugated
Gene: CETP
Gene Alias: BPI fold containing family F, BPIFF, CETP, Cholesteryl ester transfer protein, cholesteryl ester transfer protein plasma, cholesteryl ester transfer protein, plasma, HDLCQ10, Lipid transfer protein I
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1071
Content And Storage: -20°C or -80°C if preferred
Isotype: IgG
Antigen:
CETP
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.:
P11597
Gene Symbols:
CETP
Immunogen:
A synthesized peptide derived from human CETP
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Immunohistochemistry (Paraffin)
Clone:
2F1
Conjugate:
Unconjugated
Gene:
CETP
Gene Alias:
BPI fold containing family F, BPIFF, CETP, Cholesteryl ester transfer protein, cholesteryl ester transfer protein plasma, cholesteryl ester transfer protein, plasma, HDLCQ10, Lipid transfer protein I
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1071
Content And Storage:
-20°C or -80°C if preferred
Isotype:
IgG
Antigen: Lamin A
Classification: Recombinant Monoclonal
Concentration: 0.6 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.: P02545
Gene Symbols: LMNA
Immunogen: A synthesized peptide derived from human LMNA
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation
Clone: 4H7
Conjugate: Unconjugated
Gene: LMNA
Gene Alias: 70 kDa lamin, CDCD1, CDDC, CMD1A, CMT2B1, Dhe, EMD2, FPL, FPLD, FPLD2, HGPS, IDC, lamin, lamin A, lamin A/C, lamin A/C-like 1, lamin C, lamin C2, lamin-A/C, LDP1, LFP, LGMD1B, LMN1, Lmna, LMNA protein, LMNC, LMNL1, OTTHUMP00000015843, OTTHUMP00000015846, OTTHUMP00000015847, Prelamin-A/C, PRO1, renal carcinoma antigen NY-REN-32, unnamed protein product
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4000
Content And Storage: -20°C or -80°C if preferred
Isotype: IgG
Antigen:
Lamin A
Classification:
Recombinant Monoclonal
Concentration:
0.6 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.:
P02545
Gene Symbols:
LMNA
Immunogen:
A synthesized peptide derived from human LMNA
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation
Clone:
4H7
Conjugate:
Unconjugated
Gene:
LMNA
Gene Alias:
70 kDa lamin, CDCD1, CDDC, CMD1A, CMT2B1, Dhe, EMD2, FPL, FPLD, FPLD2, HGPS, IDC, lamin, lamin A, lamin A/C, lamin A/C-like 1, lamin C, lamin C2, lamin-A/C, LDP1, LFP, LGMD1B, LMN1, Lmna, LMNA protein, LMNC, LMNL1, OTTHUMP00000015843, OTTHUMP00000015846, OTTHUMP00000015847, Prelamin-A/C, PRO1, renal carcinoma antigen NY-REN-32, unnamed protein product
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4000
Content And Storage:
-20°C or -80°C if preferred
Isotype:
IgG
Antigen: FOXO3A
Classification: Recombinant Monoclonal
Concentration: 1.5 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.: O43524
Gene Symbols: FOXO3
Immunogen: A synthesized peptide derived from human FOXO3
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: 1E2
Conjugate: Unconjugated
Gene: FOXO3
Gene Alias: 1110048B16Rik, 2010203A17Rik, AF6q21, AF6q21 protein, C76856, Fkhr2, FKHRL1, FKHRL1P2, forkhead box O3, forkhead box O3a, forkhead box O3A transcription factor, forkhead box protein O3, forkhead homolog (rhabdomyosarcoma) like 1, forkhead in rhabdomyosarcoma-like 1, forkhead protein FKHR2, forkhead, Drosophila, homolog of, in rhabdomyosarcoma-like 1, FOXO2, FOXO3, FOXO-3, FOXO3A
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 2309
Content And Storage: -20°C or -80°C if preferred
Isotype: IgG
Antigen:
FOXO3A
Classification:
Recombinant Monoclonal
Concentration:
1.5 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.:
O43524
Gene Symbols:
FOXO3
Immunogen:
A synthesized peptide derived from human FOXO3
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
1E2
Conjugate:
Unconjugated
Gene:
FOXO3
Gene Alias:
1110048B16Rik, 2010203A17Rik, AF6q21, AF6q21 protein, C76856, Fkhr2, FKHRL1, FKHRL1P2, forkhead box O3, forkhead box O3a, forkhead box O3A transcription factor, forkhead box protein O3, forkhead homolog (rhabdomyosarcoma) like 1, forkhead in rhabdomyosarcoma-like 1, forkhead protein FKHR2, forkhead, Drosophila, homolog of, in rhabdomyosarcoma-like 1, FOXO2, FOXO3, FOXO-3, FOXO3A
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2309
Content And Storage:
-20°C or -80°C if preferred
Isotype:
IgG