FEMA549817

IKK beta Recombinant Rabbit Monoclonal Antibody (5D12), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA549817-Each-of-1 In Stock ₹ 35,764.08

FEMA549817 - Each of 1

₹ 35,764.08

In Stock

Quantity

1

Base Price: ₹ 35,764.08

GST (18%): ₹ 6,437.534

Total Price: ₹ 42,201.614

Antigen

IKK beta

Classification

Recombinant Monoclonal

Concentration

1.5 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.

O14920

Gene Symbols

Ikbkb

Immunogen

A synthesized peptide derived from human IKK beta

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Western Blot

Clone

5D12

Conjugate

Unconjugated

Gene

Ikbkb

Gene Alias

AI132552, AIM-1, FLJ40509, I-kappa-B kinase 2, I-kappa-B-kinase beta, Ikbkb, IKK[b], IKK2, IKK-2, IKKB, IKK-B, IKKbeta, IKK-beta, IMD15, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta, inhibitor of kappaB kinase beta, inhibitor of nuclear factor kappa B kinase beta subunit, inhibitor of nuclear factor kappa-B kinase subunit beta, MGC131801, NFKBIKB, nuclear factor NF-kappa-B inhibitor kinase beta

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3551

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG

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Description

  • Phosphorylation of serine residues on the I-kappa-B proteins by IKK kinases, including IKBKB, marks them for destruction via the ubiquitination pathway, allowing activation of the NF-kappa-B complex
  • Inhibitor of nuclear factor kappa-B kinase subunit beta (IKK beta) is a serine kinase that plays an essential role in the NF-kaapa-B signaling pathway which is activated by mulitple stimuli such as inflammatory cytokines, bacterial, or viral products, DNA damages, or other cellular stresses
  • IKK beta acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues
  • These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome
  • In turn, free NF-kappa-B is translocated into the nucleus and activates the transcription of hundreds of genes involved in immune response, growth control, or protection against apoptosis
  • Mutations affecting the IKK beta gene can result in Immunodeficiency 15 (IMD15).

Compare Similar Items

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Thermo Scientific

FEMA549817

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Antigen:
IKK beta

Classification:
Recombinant Monoclonal

Concentration:
1.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
O14920

Gene Symbols:
Ikbkb

Immunogen:
A synthesized peptide derived from human IKK beta

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Western Blot

Clone:
5D12

Conjugate:
Unconjugated

Gene:
Ikbkb

Gene Alias:
AI132552, AIM-1, FLJ40509, I-kappa-B kinase 2, I-kappa-B-kinase beta, Ikbkb, IKK[b], IKK2, IKK-2, IKKB, IKK-B, IKKbeta, IKK-beta, IMD15, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta, inhibitor of kappaB kinase beta, inhibitor of nuclear factor kappa B kinase beta subunit, inhibitor of nuclear factor kappa-B kinase subunit beta, MGC131801, NFKBIKB, nuclear factor NF-kappa-B inhibitor kinase beta

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3551

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

Img

Thermo Scientific

FEMA549818

--


Antigen:
ILK

Classification:
Recombinant Monoclonal

Concentration:
0.4 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
O55222, Q13418

Gene Symbols:
ILK

Immunogen:
A synthesized peptide derived from human ILK

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
6A5

Conjugate:
Unconjugated

Gene:
ILK

Gene Alias:
59 kDa serine/threonine-protein kinase, AA511515, epididymis secretory protein Li 28, ESTM24, HEL-S-28, ILK, ILK1, ILK-1, ILK2, ILK-2, integrin binding protein kinase, Integrin linked ILK, integrin linked kinase, integrin-linked kinase, integrin-linked kinase-2, integrin-linked protein kinase, loc, lost-contact, main squeeze, msq, P59, p59ILK, zgc:65842, zilk

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16202, 3611

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

Img

Thermo Scientific

FEMA549820

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Antigen:
Caspase 2

Classification:
Recombinant Monoclonal

Concentration:
3 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P42575

Gene Symbols:
CASP2

Immunogen:
A synthesized peptide derived from human Caspase-2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Western Blot

Clone:
7E5

Conjugate:
Unconjugated

Gene:
CASP2

Gene Alias:
CASP2, CASP-2, caspase 2, caspase 2 apoptosis-related cysteine peptidase, caspase-2, Caspase-2 subunit p12, Caspase-2 subunit p13, Caspase-2 subunit p18, ICH1, ICH-1, ICH-1 protease, ICH-1L, ICH-1L/1S, NEDD2, NEDD-2, Neural precursor cell expressed developmentally down-regulated protein 2, PPP1R57, Protease ICH-1, protein phosphatase 1, regulatory subunit 57

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
835

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

Img

Thermo Scientific

FEMA549821

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Antigen:
RET

Classification:
Recombinant Monoclonal

Concentration:
0.8 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P07949

Gene Symbols:
RET

Immunogen:
A synthesized peptide derived from human Ret

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Flow Cytometry

Clone:
8D12

Conjugate:
Unconjugated

Gene:
RET

Gene Alias:
Cadherin family member 12, Cadherin family member 12 (CDHF12), Cadherin related family member 16 (CDHR16), cadherin-related family member 16, CDHF12, CDHR16, CG1061, CG14396, CG14396-PA, CG14396-PB, CG14396-PC, c-Ret, CUX1/RET fusion, Dmel\CG14396, Dmel_CG14396, DmHD-59, DmRet, Dret, D-ret, EC 2.7.10.1, ELKS, Extracellular cell-membrane anchored RET cadherin 120 kDa fragment, HD-59, HSCR1, Hydroxyaryl protein kinase, hydroxyaryl-protein kinase, kinase Ret, MEN2, MEN2A, MEN2B, MTC1, Multiple endocrine neoplasia and medullary thyroid carcinoma 1, Oncogene RET, OTTHUMP00000216967, proto-oncogene c-Ret, Proto-oncogene tyrosine-protein kinase receptor Ret, PTC, rearranged during transfection, receptor tyrosine kinase, ret, RET ELE1, Ret gene for receptor tyrosin, Ret oncogene, ret proto-oncogene, ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease), Ret proto-oncogene (multiple endocrine neoplasia MEN2A MEN2B and medullary thyroid carcinoma 1 Hirschsprung disease), RET receptor tyrosine kinase, RET transforming sequence, RET51, RET9, RET-ELE1, Reto, Ret-PA, Ret-PB, Ret-PC, Soluble RET kinase fragment

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5979

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG