FEMA550165

EBI3 Recombinant Rabbit Monoclonal Antibody (12H5), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA550165-Each-of-1 In Stock ₹ 35,764.08

FEMA550165 - Each of 1

₹ 35,764.08

In Stock

Quantity

1

Base Price: ₹ 35,764.08

GST (18%): ₹ 6,437.534

Total Price: ₹ 42,201.614

Antigen

EBI3

Classification

Recombinant Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.

Q14213

Gene Symbols

EBI3

Immunogen

A synthesized peptide derived from Human EBI3

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Western Blot

Clone

12H5

Conjugate

Unconjugated

Gene

EBI3

Gene Alias

cytokine receptor, EBI3, EBI-3, EBV-induced gene 3 protein, Epstein-Barr virus induced 3, Epstein-Barr virus induced gene 3, Epstein-Barr virus induced gene 3 (similar to Interleukin-27 beta chain precursor), epstein-Barr virus-induced gene 3 protein, Epstein-Barr virus-induced gene 3 protein homolog, IL-27, IL27 subunit, IL-27 subunit beta, IL27B, IL-27B, IL35 subunit, interleukin-27 subunit beta

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10148

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG

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Description

  • EBI3 (Epstein-Barr virus Induced-3) is a secreted glycoprotein of the hematopoietin receptor family
  • It plays a critical regulatory role in the induction of Th2-type immune responses and the development of Th2-mediated tissue inflammation in vivo, which may be mediated through the control of iNKT cell function
  • EBI3 dimerizes with p28 and p35 subunits of IL-12 to form new proteins IL-27 and IL-35, respectively
  • IL-27 is an early product of activated antigen presenting cell that is produced upon TLR ligation
  • It negatively regulates Th17 cell differentiation
  • EBI3 is widely expressed and its expression in dendritic cell is transcriptionally regulated by TLR signaling via MyD88 and NF-kappaB during innate immune responses preceding cytokine driven Th cell development
  • EBI3 signal inhibits delayed-type hypersensitivity responses by suppressing IL-17 production and inducing IL-10 hyperproduction
  • EBI3 may play a novel role in controlling tumor metastasis via lung CD8+ T cells, and its deficiency is associated with a diminished production of Th2 cytokines which are known to regulate allergic airway inflammation in asthma
  • Targeted deletion of EBI3 protects mice from lung metastasis.

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Thermo Scientific

FEMA550165

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Antigen:
EBI3

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
Q14213

Gene Symbols:
EBI3

Immunogen:
A synthesized peptide derived from Human EBI3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Western Blot

Clone:
12H5

Conjugate:
Unconjugated

Gene:
EBI3

Gene Alias:
cytokine receptor, EBI3, EBI-3, EBV-induced gene 3 protein, Epstein-Barr virus induced 3, Epstein-Barr virus induced gene 3, Epstein-Barr virus induced gene 3 (similar to Interleukin-27 beta chain precursor), epstein-Barr virus-induced gene 3 protein, Epstein-Barr virus-induced gene 3 protein homolog, IL-27, IL27 subunit, IL-27 subunit beta, IL27B, IL-27B, IL35 subunit, interleukin-27 subunit beta

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10148

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

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Thermo Scientific

FEMA550166

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Antigen:
NAIP

Classification:
Recombinant Monoclonal

Concentration:
1.03 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
Q13075

Gene Symbols:
NAIP

Immunogen:
A synthesized peptide derived from Human NAIP

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin)

Clone:
13E6

Conjugate:
Unconjugated

Gene:
NAIP

Gene Alias:
AV364616, baculoviral IAP repeat-containing 1a, baculoviral IAP repeat-containing protein 1, Baculoviral IAP repeat-containing protein 1a, BIRC1, Birc1a, D13Lsd1, FLJ18088, FLJ42520, FLJ58811, Naip, Naip1, Naip-rs1, Neuronal apoptosis inhibitory protein, neuronal apoptosis inhibitory protein 1, NLR family apoptosis inhibitory protein, NLR family, apoptosis inhibitory protein, NLR family, apoptosis inhibitory protein 1, NLRB1, nucleotide-binding oligomerization domain, leucine rich repeat and BIR domain containing 1, psi neuronal apoptosis inhibitory protein, psiNAIP

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4671

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

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FEMA550167

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Antigen:
MICA

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
Q29983

Gene Symbols:
MICA

Immunogen:
A synthesized peptide derived from Human MICA

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin)

Clone:
9F1

Conjugate:
Unconjugated

Gene:
MICA

Gene Alias:
DAMA-345G11.2, HLA class I antigen, MHC class I chain-related protein A, MHC class I polypeptide-related sequence A, MHC class I related sequence A, MICA, MIC-A, PERB11.1, stress inducible class I homolog, truncated MHC class I polypeptide-related sequence A

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100507436

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

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FEMA550168

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Antigen:
HSD3B1

Classification:
Recombinant Monoclonal

Concentration:
1.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P14060

Gene Symbols:
HSD3B1

Immunogen:
A synthesized peptide derived from Human HSD3B1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin)

Clone:
10G2

Conjugate:
Unconjugated

Gene:
HSD3B1

Gene Alias:
3 beta-hydroxysteroid dehydrogenase 1; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I; 3BETAHSD; 3-beta-HSD; 3-beta-HSD I; 3-beta-hydroxy-5-ene steroid dehydrogenase; 3-beta-hydroxy-Delta(5)-steroid dehydrogenase; 3-beta-hydroxysteroid 3-dehydrogenase; 3BH; Delta-5-3-ketosteroid isomerase; Dihydrotestosterone oxidoreductase; HGNC:5217; HSD3B; Hsd3b1; HSDB3; HSDB3A; hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1; hydroxy-delta-MAY-steroid dehydrogenase, 3 beta- and steroid delta-isomerase; hydroxysteroid dehydrogenase-1, delta<5>-3-beta; I; Progesterone reductase; SDR11E1; short chain dehydrogenase/reductase family 11E, member 1; steroid Delta-isomerase; Trophoblast antigen FDO161G; unnamed protein product

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3283

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG