FEMA549985
CD11a Recombinant Rabbit Monoclonal Antibody (2B2), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA549985-Each-of-1 | In Stock | ₹ 35,764.08 |
FEMA549985 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 35,764.08
GST (18%): ₹ 6,437.534
Total Price: ₹ 42,201.614
Antigen
CD11a
Classification
Recombinant Monoclonal
Concentration
0.8 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.
P20701
Gene Symbols
ITGAL
Immunogen
A synthesized peptide derived from human ITGAL
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
ELISA, Immunocytochemistry, Western Blot
Clone
2B2
Conjugate
Unconjugated
Gene
ITGAL
Gene Alias
(p180), alpha L integrin, antigen CD11A (p180), antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide, antigen CD11A p180, CD11 antigen-like family member A, CD11a, integrin alpha L, integrin alphaL, integrin alpha-L, integrin alpha-L precursor, integrin gene promoter, integrin subunit alpha L, integrin surface receptor, integrin, alpha L, integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide), ITGAL, Leukocyte adhesion glycoprotein LFA-1 alpha chain, leukocyte function-associated molecule 1 alpha chain, LFA-1, LFA-1 alpha, LFA1A, LFA-1A, Ly-15, Ly-21, lymphocyte antigen 15, lymphocyte function associated antigen 1, alpha polypeptide, lymphocyte function-associated antigen 1, lymphocyte function-associated antigen 1, alpha polypeptide, lymphocyte function-associated antigen-1
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
3683
Content And Storage
-20°C or -80°C if preferred
Isotype
IgG
Related Products
Description
- CD11a (LFA-1 alpha, ITGAL) together with CD18 constitute leukocyte function-associated antigen 1 (LFA-1), the alphaLbeta2 integrin
- CD11a is implicated in activation of LFA-1 complex
- CD11a plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling
- CD11a is expressed on the plasma membrane of leukocytes in a low-affinity conformation
- Cell stimulation by chemokines or other signals leads to induction the high-affinity conformation, which supports tight binding of CD11a to its ligands, the intercellular adhesion molecules ICAM-1, -2, -3
- CD11a is thus involved in interaction of various immune cells and in their tissue-specific settlement, but participates also in control of cell differentiation and proliferation and of T-cell effector functions
- Blocking of CD11a function by specific antibodies or small molecules has become an important therapeutic approach in treatment of multiple inflammatory diseases
- For example, humanized anti- CD11a antibody Efalizumab (Raptiva) is being used to interfere with T cell migration to sites of inflammation, binding of cholesterol-lowering drug simvastatin to CD11a allosteric site leads to immunomodulation and increase in lymphocytic cholinergic activity
- Two transcript variants encoding different isoforms of CD11a have been found
- Diseases associated with CD11a dysfunction include benign cephalic histiocytosis and leukocyte adhesion deficiency.
Compare Similar Items
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Antigen: CD11a
Classification: Recombinant Monoclonal
Concentration: 0.8 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.: P20701
Gene Symbols: ITGAL
Immunogen: A synthesized peptide derived from human ITGAL
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Immunocytochemistry, Western Blot
Clone: 2B2
Conjugate: Unconjugated
Gene: ITGAL
Gene Alias: (p180), alpha L integrin, antigen CD11A (p180), antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide, antigen CD11A p180, CD11 antigen-like family member A, CD11a, integrin alpha L, integrin alphaL, integrin alpha-L, integrin alpha-L precursor, integrin gene promoter, integrin subunit alpha L, integrin surface receptor, integrin, alpha L, integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide), ITGAL, Leukocyte adhesion glycoprotein LFA-1 alpha chain, leukocyte function-associated molecule 1 alpha chain, LFA-1, LFA-1 alpha, LFA1A, LFA-1A, Ly-15, Ly-21, lymphocyte antigen 15, lymphocyte function associated antigen 1, alpha polypeptide, lymphocyte function-associated antigen 1, lymphocyte function-associated antigen 1, alpha polypeptide, lymphocyte function-associated antigen-1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3683
Content And Storage: -20°C or -80°C if preferred
Isotype: IgG
Antigen:
CD11a
Classification:
Recombinant Monoclonal
Concentration:
0.8 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.:
P20701
Gene Symbols:
ITGAL
Immunogen:
A synthesized peptide derived from human ITGAL
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Immunocytochemistry, Western Blot
Clone:
2B2
Conjugate:
Unconjugated
Gene:
ITGAL
Gene Alias:
(p180), alpha L integrin, antigen CD11A (p180), antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide, antigen CD11A p180, CD11 antigen-like family member A, CD11a, integrin alpha L, integrin alphaL, integrin alpha-L, integrin alpha-L precursor, integrin gene promoter, integrin subunit alpha L, integrin surface receptor, integrin, alpha L, integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide), ITGAL, Leukocyte adhesion glycoprotein LFA-1 alpha chain, leukocyte function-associated molecule 1 alpha chain, LFA-1, LFA-1 alpha, LFA1A, LFA-1A, Ly-15, Ly-21, lymphocyte antigen 15, lymphocyte function associated antigen 1, alpha polypeptide, lymphocyte function-associated antigen 1, lymphocyte function-associated antigen 1, alpha polypeptide, lymphocyte function-associated antigen-1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3683
Content And Storage:
-20°C or -80°C if preferred
Isotype:
IgG
Antigen: MST2
Classification: Recombinant Monoclonal
Concentration: 0.4 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.: Q13188
Gene Symbols: STK3
Immunogen: A synthesized peptide derived from human STK3
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Western Blot
Clone: 3C3
Conjugate: Unconjugated
Gene: STK3
Gene Alias: 0610042I06Rik, KB-1458E12.1, KRS1, Mammalian STE20-like protein kinase 2, mess1, MST, Mst2, MST-2, MST2/C, MST2/N, Mst3, protein kinase homolog, serine/threonine kinase 3, serine/threonine kinase 3 (STE20 homolog, yeast), serine/threonine kinase 3 (Ste20, yeast homolog), serine/threonine-protein kinase 3, Serine/threonine-protein kinase 3 20kDa subunit, Serine/threonine-protein kinase 3 36kDa subunit, Serine/threonine-protein kinase Krs-1, Ste20, STE20-like kinase MST2, STK3, wu:fc19e11, zgc:55383
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 6788
Content And Storage: -20°C or -80°C if preferred
Isotype: IgG
Antigen:
MST2
Classification:
Recombinant Monoclonal
Concentration:
0.4 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.:
Q13188
Gene Symbols:
STK3
Immunogen:
A synthesized peptide derived from human STK3
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Western Blot
Clone:
3C3
Conjugate:
Unconjugated
Gene:
STK3
Gene Alias:
0610042I06Rik, KB-1458E12.1, KRS1, Mammalian STE20-like protein kinase 2, mess1, MST, Mst2, MST-2, MST2/C, MST2/N, Mst3, protein kinase homolog, serine/threonine kinase 3, serine/threonine kinase 3 (STE20 homolog, yeast), serine/threonine kinase 3 (Ste20, yeast homolog), serine/threonine-protein kinase 3, Serine/threonine-protein kinase 3 20kDa subunit, Serine/threonine-protein kinase 3 36kDa subunit, Serine/threonine-protein kinase Krs-1, Ste20, STE20-like kinase MST2, STK3, wu:fc19e11, zgc:55383
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
6788
Content And Storage:
-20°C or -80°C if preferred
Isotype:
IgG
Antigen: 14-3-3 beta
Classification: Recombinant Monoclonal
Concentration: 0.11 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.: P31946, P35213, Q9CQV8
Gene Symbols: YWHAB
Immunogen: A synthesized peptide derived from human YWHAB
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Liquid
Applications: ELISA, Flow Cytometry, Immunocytochemistry, Western Blot
Clone: 6F6
Conjugate: Unconjugated
Gene: YWHAB
Gene Alias: 1300003C17Rik, 14-3-3 alpha, 14-3-3 protein beta, 14-3-3 protein beta/alpha, 14-3-3 protein beta/alpha, N-terminally processed, 14-3-3 protein beta-subtype, 3-monooxygenase/tryptophan 5 monooxygenase activation protein beta polypeptide, brain protein 14-3-3, beta isoform, epididymis secretory protein Li 1, GW128, HEL-S-1, HS1, hypothetical protein GW128, KCIP 1, KCIP1, KCIP-1, Prepronerve growth factor RNH-1, protein 1054, Protein kinase C inhibitor protein 1, protein kinase C inhibitor protein-1, QccE-16215, RP1-148E22.1, tryosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta polypeptide, tryosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma, tyrosine 3/tryptophan 5 -monooxygenase activation protein beta polypeptide, tyrosine 3/tryptophan 5 -monooxygenase activation protein, beta polypeptide, tyrosine 3-monooxgenase/tryptophan 5 monooxgenase activation protein beta polypeptide, tyrosine 3-monooxgenase/tryptophan 5 monooxgenase activation protein, beta polypeptide, tyrosine 3-monooxgenase/tryptophan 5-monooxgenase activation protein, beta polypeptide, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, alpha polypeptide, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide, unnamed protein product, YWHAA, Ywhab
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 54401, 56011, 7529
Content And Storage: -20°C or -80°C if preferred
Isotype: IgG
Antigen:
14-3-3 beta
Classification:
Recombinant Monoclonal
Concentration:
0.11 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.:
P31946, P35213, Q9CQV8
Gene Symbols:
YWHAB
Immunogen:
A synthesized peptide derived from human YWHAB
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Liquid
Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Western Blot
Clone:
6F6
Conjugate:
Unconjugated
Gene:
YWHAB
Gene Alias:
1300003C17Rik, 14-3-3 alpha, 14-3-3 protein beta, 14-3-3 protein beta/alpha, 14-3-3 protein beta/alpha, N-terminally processed, 14-3-3 protein beta-subtype, 3-monooxygenase/tryptophan 5 monooxygenase activation protein beta polypeptide, brain protein 14-3-3, beta isoform, epididymis secretory protein Li 1, GW128, HEL-S-1, HS1, hypothetical protein GW128, KCIP 1, KCIP1, KCIP-1, Prepronerve growth factor RNH-1, protein 1054, Protein kinase C inhibitor protein 1, protein kinase C inhibitor protein-1, QccE-16215, RP1-148E22.1, tryosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta polypeptide, tryosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma, tyrosine 3/tryptophan 5 -monooxygenase activation protein beta polypeptide, tyrosine 3/tryptophan 5 -monooxygenase activation protein, beta polypeptide, tyrosine 3-monooxgenase/tryptophan 5 monooxgenase activation protein beta polypeptide, tyrosine 3-monooxgenase/tryptophan 5 monooxgenase activation protein, beta polypeptide, tyrosine 3-monooxgenase/tryptophan 5-monooxgenase activation protein, beta polypeptide, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, alpha polypeptide, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide, unnamed protein product, YWHAA, Ywhab
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
54401, 56011, 7529
Content And Storage:
-20°C or -80°C if preferred
Isotype:
IgG
Antigen: HSP90 beta
Classification: Recombinant Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.: P08238
Gene Symbols: Hsp90ab1
Immunogen: A synthesized peptide derived from human HSP90AB1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: 7G7
Conjugate: Unconjugated
Gene: Hsp90ab1
Gene Alias: 90kDa, 90-kDa heat shock protein beta, AL022974, C81438, D6S182, heat shock 84 kDa, heat shock 90 kDa protein, heat shock 90kD protein 1, beta, heat shock 90kDa protein 1, beta, heat shock cognate protein HSP 90-beta, Heat shock protein, heat shock protein 1, beta, heat shock protein 90 alpha (cytosolic), class B member 1, heat shock protein 90 alpha family class B member 1, heat shock protein 90 beta, heat shock protein 90 kDa, heat shock protein 90 kDa alpha class B member 1, heat shock protein 90kDa alpha (cytosolic), class B member 1, heat shock protein 90kDa alpha family class B member 1, Heat shock protein HSP 90-beta, heat shock protein, 84 kDa 1, HSP, HSP 84, HSP 90, Hsp84, Hsp84-1, Hsp90, hsp90 beta, HSP90AB1, HSP90B, HSP90-beta, HSPC2, HSPCB, retinal degeneration slow protein, RP1-302G2.1, TSTA, Tumor-specific transplantation 84 kDa antigen, Unknown (protein for IMAGE:7943063)
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3326
Content And Storage: -20°C or -80°C if preferred
Isotype: IgG
Antigen:
HSP90 beta
Classification:
Recombinant Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.:
P08238
Gene Symbols:
Hsp90ab1
Immunogen:
A synthesized peptide derived from human HSP90AB1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
7G7
Conjugate:
Unconjugated
Gene:
Hsp90ab1
Gene Alias:
90kDa, 90-kDa heat shock protein beta, AL022974, C81438, D6S182, heat shock 84 kDa, heat shock 90 kDa protein, heat shock 90kD protein 1, beta, heat shock 90kDa protein 1, beta, heat shock cognate protein HSP 90-beta, Heat shock protein, heat shock protein 1, beta, heat shock protein 90 alpha (cytosolic), class B member 1, heat shock protein 90 alpha family class B member 1, heat shock protein 90 beta, heat shock protein 90 kDa, heat shock protein 90 kDa alpha class B member 1, heat shock protein 90kDa alpha (cytosolic), class B member 1, heat shock protein 90kDa alpha family class B member 1, Heat shock protein HSP 90-beta, heat shock protein, 84 kDa 1, HSP, HSP 84, HSP 90, Hsp84, Hsp84-1, Hsp90, hsp90 beta, HSP90AB1, HSP90B, HSP90-beta, HSPC2, HSPCB, retinal degeneration slow protein, RP1-302G2.1, TSTA, Tumor-specific transplantation 84 kDa antigen, Unknown (protein for IMAGE:7943063)
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3326
Content And Storage:
-20°C or -80°C if preferred
Isotype:
IgG