FEMA549879

ADAM17 Recombinant Rabbit Monoclonal Antibody (5A1), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA549879-Each-of-1 In Stock ₹ 35,764.08

FEMA549879 - Each of 1

₹ 35,764.08

In Stock

Quantity

1

Base Price: ₹ 35,764.08

GST (18%): ₹ 6,437.534

Total Price: ₹ 42,201.614

Antigen

ADAM17

Classification

Recombinant Monoclonal

Concentration

1.6 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.

P78536

Gene Symbols

ADAM17

Immunogen

A synthesized peptide derived from human ADAM17

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Immunocytochemistry

Clone

5A1

Conjugate

Unconjugated

Gene

ADAM17

Gene Alias

a disintegrin and metallopeptidase domain 17, a disintegrin and metalloprotease domain 17, a disintegrin and metalloproteinase, a disintegrin and metalloproteinase domain 17, a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme), ADAM, ADAM 17, ADAM metallopeptidase domain 17, ADAM metallopeptidase domain 18, Adam17, ADAM18, ADAMs, CD156B, CD156b antigen, CSVP, Disintegrin and metalloproteinase domain-containing protein 17, metalloendopeptidases, NISBD, NISBD1, Snake venom-like protease, TACE, TNF-alpha convertase, TNF-alpha converting enzyme, TNF-alpha-converting enzyme, tumor necrosis factor, alpha, converting enzyme

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

6868

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG

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Description

  • ADAM17 (disintegrin and metalloproteinase domain-containing protein 17) cleaves the membrane bound precusor of TNF-alpha to its mature soluble form
  • ADAM 17 is responsbile for the proteolytical release of soluble JAM3 from endothelial cells surface and the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin receptor type II, p55 TNF-receptor, transforming growth factor-alpha, L-selectin, growth hormone receptor, MUC1, and the amyloid precursor protein
  • It acts as an activator of the Notch pathway by mediating cleavage of Notch and generating the membrane-associated intermediate fragment called Notch extracellular truncation (NEXT)
  • Mutations in the gene can result in inflammatory skin and bowel disease, neonatal 1.

Compare Similar Items

Show Difference

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Thermo Scientific

FEMA549879

--


Antigen:
ADAM17

Classification:
Recombinant Monoclonal

Concentration:
1.6 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P78536

Gene Symbols:
ADAM17

Immunogen:
A synthesized peptide derived from human ADAM17

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunocytochemistry

Clone:
5A1

Conjugate:
Unconjugated

Gene:
ADAM17

Gene Alias:
a disintegrin and metallopeptidase domain 17, a disintegrin and metalloprotease domain 17, a disintegrin and metalloproteinase, a disintegrin and metalloproteinase domain 17, a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme), ADAM, ADAM 17, ADAM metallopeptidase domain 17, ADAM metallopeptidase domain 18, Adam17, ADAM18, ADAMs, CD156B, CD156b antigen, CSVP, Disintegrin and metalloproteinase domain-containing protein 17, metalloendopeptidases, NISBD, NISBD1, Snake venom-like protease, TACE, TNF-alpha convertase, TNF-alpha converting enzyme, TNF-alpha-converting enzyme, tumor necrosis factor, alpha, converting enzyme

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6868

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

Img

Thermo Scientific

FEMA549883

--


Antigen:
PAK2

Classification:
Recombinant Monoclonal

Concentration:
0.53 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
Q13177, Q64303, Q8CIN4

Gene Symbols:
Pak2

Immunogen:
A synthesized peptide derived from human PAK2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunoprecipitation, Western Blot

Clone:
6D12

Conjugate:
Unconjugated

Gene:
Pak2

Gene Alias:
5330420P17Rik, A130002K10Rik, AI836325, Alpha-PAK, Beta-PAK, C-t-PAK2, D16Ertd269e, gamma pak, gamma-PAK, mKIAA4182, Oligophrenin-3, OPHN3, p21 (CDKN1A)-activated kinase 2, p21 (RAC1) activated kinase 2, p21 protein (Cdc42/Rac)-activated kinase 2, p21-activated kinase 2, p27, p34, p58, p65-PAK, PAK alpha, PAK beta, PAK gamma, PAK1, PAK-1, Pak2, PAK-2, PAK-2p27, PAK-2p34, PAK3, PAK-3, PAK65, PAKgamma, S6/H4 kinase, serine/threonine-protein kinase PAK 2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
224105, 29432, 5062

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

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FEMA549884

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Antigen:
Huntingtin

Classification:
Recombinant Monoclonal

Concentration:
0.63 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P42858

Gene Symbols:
Htt

Immunogen:
A synthesized peptide derived from human Huntingtin

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin)

Clone:
6F2

Conjugate:
Unconjugated

Gene:
Htt

Gene Alias:
AI256365, C430023I11Rik, Hd, HD protein, HD protein homolog, Hdh, HTT, Huntingtin, huntingtin (Huntington disease), Huntingtin, myristoylated N-terminal fragment, Huntington disease gene homolog, huntington disease protein, huntington disease protein homolog, IT15, solute carrier family 6 (neurotransmitter transporter, serotonin), member 4

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3064

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

Img

Thermo Scientific

FEMA549885

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Antigen:
B-Raf

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P15056

Gene Symbols:
BRAF

Immunogen:
A synthesized peptide derived from human B Raf

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin)

Clone:
6G3

Conjugate:
Unconjugated

Gene:
BRAF

Gene Alias:
94 kDa B-raf protein, 9930012E13Rik, AA120551, AA387315, AA473386, Braf, B-raf, B-raf protein, B-raf protein isoform 1, B-raf protein isoform 2, B-Raf proto-oncogene serine/threonine-protein kinase, B-Raf proto-oncogene serine/threonine-protein kinase (p94), B-Raf proto-oncogene, serine/threonine kinase, Braf transforming gene, BRAF1, B-RAF1, Braf2, Braf-2, C230098H17, C87398, C-RMIL, D6Ertd631e, FLJ95109, MGC126806, murine sarcoma viral (v-raf) oncogene homolog B1, NS7, p94, Proto-oncogene B-Raf, proto-oncogene c-Rmil, RAFB1, RMIL, rmil serine/threonine-protein kinase, serine/threonine kinase, serine/threonine-protein kinase B-raf, Serine/threonine-protein kinase Rmil, v-raf murine sarcoma viral oncogene homolog B, v-raf murine sarcoma viral oncogene homolog B1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
673

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG