FEMA549957

HSF1 Recombinant Rabbit Monoclonal Antibody (5C7), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA549957-Each-of-1 In Stock ₹ 35,764.08

FEMA549957 - Each of 1

₹ 35,764.08

In Stock

Quantity

1

Base Price: ₹ 35,764.08

GST (18%): ₹ 6,437.534

Total Price: ₹ 42,201.614

Antigen

HSF1

Classification

Recombinant Monoclonal

Concentration

0.28 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.

Q00613

Gene Symbols

Hsf1

Immunogen

A synthesized peptide derived from human HSF1

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Immunohistochemistry (Paraffin)

Clone

5C7

Conjugate

Unconjugated

Gene

Hsf1

Gene Alias

AA960185, heat shock factor 1, heat shock factor 2, Heat shock factor protein 1, Heat shock transcription factor 1, heat shock transcription factor 1 alpha isoform, heat shock transcription factor 1 beta isoform, heat shock transcription factor 1 gammaalpha isoform, heat shock transcription factor 1 gammabeta isoform, HSF, HSF 1, Hsf1, Hsf1alpha, Hsf1beta, Hsf1gammaalpha, Hsf1gammabeta, HSTF 1, HSTF1

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3297

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG

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Description

  • All organisms respond to elevated temperatures and a variety of environmental stresses by rapid synthesis of heat shock RNAs and proteins
  • The regulation of heat shock gene transcription is mediated by the transcriptional activator, heat shock factor (HSF), which binds to heat shock response elements (HSEs)
  • These HSEs are found as three repeats of a 5-nucleotide {nGAAn} module, arranged in alternating orientation and present upstream of all heat shock genes
  • The HSEs are highly conserved among species yet HSF purified from yeast, Drosophila and human have different molecular weights and the proteins do not show significant immunological cross reaction
  • Two HSFs have been identified in human cells, HSF1 and HSF2, which bind to the same HSEs and have 38% sequence identity
  • These factors are activated by distinct stimuli, HSF1 is responsive to classical stress signals such as heat, heavy metals and oxidative reagents, whereas HSF2 is activated during hemin-mediated differentiation of human erythroleukemia cells
  • HSF1 exists constitutively in the cytoplasm and the nucleus of unstressed cells as a monomer which lacks DNA binding activity
  • Through an unknown signal generated during stress, HSF1 becomes activated to a nuclear localized, trimeric state which binds to DNA
  • The phosphorylation of HSF1 is necessary for maximal transcription of heat shock genes.

Compare Similar Items

Show Difference

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Thermo Scientific

FEMA549957

--


Antigen:
HSF1

Classification:
Recombinant Monoclonal

Concentration:
0.28 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
Q00613

Gene Symbols:
Hsf1

Immunogen:
A synthesized peptide derived from human HSF1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin)

Clone:
5C7

Conjugate:
Unconjugated

Gene:
Hsf1

Gene Alias:
AA960185, heat shock factor 1, heat shock factor 2, Heat shock factor protein 1, Heat shock transcription factor 1, heat shock transcription factor 1 alpha isoform, heat shock transcription factor 1 beta isoform, heat shock transcription factor 1 gammaalpha isoform, heat shock transcription factor 1 gammabeta isoform, HSF, HSF 1, Hsf1, Hsf1alpha, Hsf1beta, Hsf1gammaalpha, Hsf1gammabeta, HSTF 1, HSTF1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3297

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

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FEMA549958

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Antigen:
SOX9

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P48436

Gene Symbols:
SOX9

Immunogen:
A synthesized peptide derived from human SOX9

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin)

Clone:
5H12

Conjugate:
Unconjugated

Gene:
SOX9

Gene Alias:
2010306G03Rik, AV220920, CMD1, CMPD1, mKIAA4243, SOX 9, Sox9, SOX-9, Sox9 transcription factor, SRA1, SRXX2, SRXY10, SRY (sex determining region Y)-box 9, SRY (sex determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal), SRY (sex determining region Y)-box9, SRY (sex-determining region Y)-box 9 protein, SRY box 9, SRY-box 9, SRY-Box 9 , SRY-box containing 9, SRY-box containing gene 9, SRY-box containing protein 9, SRY-box transcription factor 9, SRY-related HMG-box, gene 9, transcription activator Sox9, transcription factor SOX-9

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6662

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

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FEMA549962

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Antigen:
LTA4H

Classification:
Recombinant Monoclonal

Concentration:
0.18 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P09960, P24527

Gene Symbols:
LTA4H

Immunogen:
A synthesized peptide derived from human LTA4H

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Liquid

Applications:
ELISA, Western Blot

Clone:
6G7

Conjugate:
Unconjugated

Gene:
LTA4H

Gene Alias:
Leukotriene A(4) hydrolase, leukotriene A4 hydrolase, Leukotriene A-4 hydrolase, LKHA4, LTA4, LTA4 hydrodase, LTA-4 hydrolase, LTA4H, testicular secretory protein Li 27

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16993, 4048

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

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FEMA549964

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Antigen:
Claudin 18

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% Proclin 300, pH 7.4

Gene Accession No.:
P56856

Gene Symbols:
Cldn18

Immunogen:
Recombinant Human CLDN18 protein

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Neutralization

Clone:
25E3

Conjugate:
Unconjugated

Gene:
Cldn18

Gene Alias:
claudin 18, claudin 18-like, claudin-18, CLDN18, SFTA5, SFTPJ, surfactant associated 5, surfactant associated protein J, surfactant, pulmonary associated protein J, UNQ778/PRO1572

Host Species:
Human

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
51208

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG1