FEMA550089

PD-1 Recombinant Human Monoclonal Antibody (9A9), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA550089-Each-of-1 In Stock ₹ 35,764.08

FEMA550089 - Each of 1

₹ 35,764.08

In Stock

Quantity

1

Base Price: ₹ 35,764.08

GST (18%): ₹ 6,437.534

Total Price: ₹ 42,201.614

Antigen

PD-1

Classification

Recombinant Monoclonal

Concentration

0.1 mg/mL

Formulation

PBS with 50% glycerol and 0.03% Proclin 300, pH 7.4

Gene Accession No.

Q15116

Gene Symbols

Pdcd1

Immunogen

Recombinant Human PD-1 protein

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Neutralization

Clone

9A9

Conjugate

Unconjugated

Gene

Pdcd1

Gene Alias

CD279, EGK_05005, hPD1, hPD-1, hPD-l, hSLE1, Ly101, mPD-1, PD1, PD-1, Pdc1, Pdcd1, programmed cell death 1, programmed cell death 1 protein, programmed cell death protein 1, programmed cell death protein 1-like, programmed death 1, Protein PD1, protein PD-1, sCD279, SLEB2, soluble CD279, systemic lupus erythematosus susceptibility 2

Host Species

Human

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

5133

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG4

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Description

  • Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antig en-presenting cells (APC)
  • T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC
  • PD-1 can bind two different but related ligands, PDL-1 and PDL-2
  • Upon binding to either of these ligands, signals generated by PD-1 inhibit the activation of the immune response in the absence of &quotedanger signals&quote such as LPS or other molecules associated with bacteria or other pathogens
  • Evidence for this is seen in PD1-null mice who exhibit hyperactivated immune systems and autoimmune diseases
  • Despite its predicted molecular weight, PD-1 often migrates at higher molecular weight in SDS-PAGE.

Compare Similar Items

Show Difference

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Thermo Scientific

FEMA550089

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Antigen:
PD-1

Classification:
Recombinant Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% Proclin 300, pH 7.4

Gene Accession No.:
Q15116

Gene Symbols:
Pdcd1

Immunogen:
Recombinant Human PD-1 protein

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Neutralization

Clone:
9A9

Conjugate:
Unconjugated

Gene:
Pdcd1

Gene Alias:
CD279, EGK_05005, hPD1, hPD-1, hPD-l, hSLE1, Ly101, mPD-1, PD1, PD-1, Pdc1, Pdcd1, programmed cell death 1, programmed cell death 1 protein, programmed cell death protein 1, programmed cell death protein 1-like, programmed death 1, Protein PD1, protein PD-1, sCD279, SLEB2, soluble CD279, systemic lupus erythematosus susceptibility 2

Host Species:
Human

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5133

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG4

Img

Thermo Scientific

FEMA550091

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Antigen:
IL-17A

Classification:
Recombinant Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% Proclin 300, pH 7.4

Gene Accession No.:
Q16552

Gene Symbols:
IL17A

Immunogen:
Recombinant Human IL17A protein

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Neutralization

Clone:
11C11

Conjugate:
Unconjugated

Gene:
IL17A

Gene Alias:
Ctla8, CTLA-8, cytokine, cytotoxic T-lymphocyte-associated antigen 8, cytotoxic T-lymphocyte-associated protein 8, il 17, Il17, IL-17, IL17A, IL-17a, ILN, Interleukin, interleukin 17, interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8), interleukin 17 precursor, interleukin 17A, interleukin-17, Interleukin17A, interleukin-17A, R-IL-17-A

Host Species:
Human

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3605

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG4

Img

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FEMA550092

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Antigen:
VSIG4

Classification:
Recombinant Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% Proclin 300, pH 7.4

Gene Accession No.:
Q9Y279

Gene Symbols:
VSIG4

Immunogen:
Recombinant Human VSIG4 protein

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Neutralization

Clone:
12D12

Conjugate:
Unconjugated

Gene:
VSIG4

Gene Alias:
A530061A11, BC025105, complement receptor of the immunoglobulin superfamily, CRIg, Ig superfamily protein, MGC137243 protein, protein Z39Ig, UNQ317/PRO362, V-set and immunoglobulin domain containing 4, V-set and immunoglobulin domain-containing protein 4, VSIG4, Z39IG

Host Species:
Human

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11326

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG1

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FEMA550093

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Antigen:
SLC39A6

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% Proclin 300, pH 7.4

Gene Accession No.:
Q13433

Gene Symbols:
SLC39A6

Immunogen:
Recombinant Human SLC39A6 protein

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Neutralization

Clone:
13F1

Conjugate:
Unconjugated

Gene:
SLC39A6

Gene Alias:
EMBL:AAH97493.1}, endoplasmic reticulum membrane protein, endoplasmic reticulum membrane-linked protein, Ermelin, Estrogen-regulated protein LIV-1, LIV1, LIV-1, LIV-1 protein, estrogen regulated, SLC39A6, slc39a6 {ECO:0000312, solute carrier family 39 (metal ion transporter), member 6, solute carrier family 39 (zinc transporter), member 6, solute carrier family 39 member 6, Zinc transporter ZIP6, Zip6, ZIP-6, zrt- and Irt-like protein 6

Host Species:
Human

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
25800

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG1