FEMA550214
STAT3 Recombinant Human Monoclonal Antibody (28H4), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA550214-Each-of-1 | In Stock | ₹ 35,764.08 |
FEMA550214 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 35,764.08
GST (18%): ₹ 6,437.534
Total Price: ₹ 42,201.614
Antigen
STAT3
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.03% Proclin 300, pH 7.4
Gene Accession No.
P40763
Gene Symbols
STAT3
Immunogen
Recombinant Human STAT3 protein
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
ELISA, Neutralization
Clone
28H4
Conjugate
Unconjugated
Gene
STAT3
Gene Alias
1110034C02Rik, acute phase response factor, acute-phase response factor, ADMIO, ADMIO1, APRF, AW109958, DNA-binding protein APRF, FLJ20882, HIES, MGC16063, signal transducer and activator of transcription 3, signal transducer and activator of transcription 3 (acute-phase response factor), signal transducer, activator of transcription, acute-phase response factor, signal transduction and activation of transcription 3, STAT, STAT3, STAT-3, stat3 protein, STAT3b1, STAT3b2, transcription factor, Unknown (protein for MGC:128731), wu:fc15d02, wu:fl59g06, z-Stat3
Host Species
Human
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
6774
Content And Storage
-20°C or -80°C if preferred
Isotype
IgG1
Related Products
Description
- STAT3 belongs to the family of STAT (signal transducers and activators of transcription) proteins which are phosphorylated by receptor associated kinases, translocate to the nucleus, and act as transcription factors in response to cytokines and growth factors
- Coactivators such as CREB-binding protein are required for the transcriptional activation by STAT3
- STAT3 can also be activated by Interferon-alpha, Interferon-gamma, EGF, PDGF and IL6
- Phosphorylation on tyrosine 705 by JAK1 and JAK2 is essential for STAT3 dimer formation, nuclear translocation, and DNA binding activity
- In humans, the STAT3 gene is located on the q arm of chromosome 17
- STAT3 has been shown to be activated by IFN-alpha but not IFN-beta
- The transcription factors associated with STAT3 are c-Jun and cyclic AMP-responsive enhancer binding protein (CREB)
- STAT3 mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis
- The small GTPase Rac1 has been shown to bind and regulate the activity of STAT3 while the PIAS3 protein is a specific inhibitor of STAT3
- Three alternatively spliced transcript variants encoding distinct isoforms of STAT3 have been described
- Deletion of the STAT3 gene in knock-out mice was lethal at the early embryonic stage.
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Antigen: STAT3
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.03% Proclin 300, pH 7.4
Gene Accession No.: P40763
Gene Symbols: STAT3
Immunogen: Recombinant Human STAT3 protein
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Neutralization
Clone: 28H4
Conjugate: Unconjugated
Gene: STAT3
Gene Alias: 1110034C02Rik, acute phase response factor, acute-phase response factor, ADMIO, ADMIO1, APRF, AW109958, DNA-binding protein APRF, FLJ20882, HIES, MGC16063, signal transducer and activator of transcription 3, signal transducer and activator of transcription 3 (acute-phase response factor), signal transducer, activator of transcription, acute-phase response factor, signal transduction and activation of transcription 3, STAT, STAT3, STAT-3, stat3 protein, STAT3b1, STAT3b2, transcription factor, Unknown (protein for MGC:128731), wu:fc15d02, wu:fl59g06, z-Stat3
Host Species: Human
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 6774
Content And Storage: -20°C or -80°C if preferred
Isotype: IgG1
Antigen:
STAT3
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.03% Proclin 300, pH 7.4
Gene Accession No.:
P40763
Gene Symbols:
STAT3
Immunogen:
Recombinant Human STAT3 protein
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Neutralization
Clone:
28H4
Conjugate:
Unconjugated
Gene:
STAT3
Gene Alias:
1110034C02Rik, acute phase response factor, acute-phase response factor, ADMIO, ADMIO1, APRF, AW109958, DNA-binding protein APRF, FLJ20882, HIES, MGC16063, signal transducer and activator of transcription 3, signal transducer and activator of transcription 3 (acute-phase response factor), signal transducer, activator of transcription, acute-phase response factor, signal transduction and activation of transcription 3, STAT, STAT3, STAT-3, stat3 protein, STAT3b1, STAT3b2, transcription factor, Unknown (protein for MGC:128731), wu:fc15d02, wu:fl59g06, z-Stat3
Host Species:
Human
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
6774
Content And Storage:
-20°C or -80°C if preferred
Isotype:
IgG1
Antigen: ALPPL2
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.03% Proclin 300, pH 7.4
Gene Accession No.: P10696
Gene Symbols: ALPG, ALPPL2
Immunogen: Recombinant Human ALPG protein
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Neutralization
Clone: 29A5
Conjugate: Unconjugated
Gene: ALPG
Gene Alias: Akp5, alkaline phosphatase 5, Alkaline phosphatase Nagao isozyme, Alkaline phosphatase, germ cell type, alkaline phosphatase, placental like 2, alkaline phosphatase, placental-like, alkaline phosphatase, placental-like 2, ALP-1, Alpg, ALPPL, ALPPL2, C77216, D1Ertd816e, EAP, Embryonic alkaline phosphatase, embryonic-type alkaline phosphatase, GCAP, Germ cell alkaline phosphatase, Nagao isozyme, Placental alkaline phosphatase-like, placental-like alkaline phosphatase, PLAP-like, RGD1565100, testicular and thymus alkaline phosphatase
Host Species: Human
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 251
Content And Storage: -20°C or -80°C if preferred
Isotype: IgG1
Antigen:
ALPPL2
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.03% Proclin 300, pH 7.4
Gene Accession No.:
P10696
Gene Symbols:
ALPG, ALPPL2
Immunogen:
Recombinant Human ALPG protein
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Neutralization
Clone:
29A5
Conjugate:
Unconjugated
Gene:
ALPG
Gene Alias:
Akp5, alkaline phosphatase 5, Alkaline phosphatase Nagao isozyme, Alkaline phosphatase, germ cell type, alkaline phosphatase, placental like 2, alkaline phosphatase, placental-like, alkaline phosphatase, placental-like 2, ALP-1, Alpg, ALPPL, ALPPL2, C77216, D1Ertd816e, EAP, Embryonic alkaline phosphatase, embryonic-type alkaline phosphatase, GCAP, Germ cell alkaline phosphatase, Nagao isozyme, Placental alkaline phosphatase-like, placental-like alkaline phosphatase, PLAP-like, RGD1565100, testicular and thymus alkaline phosphatase
Host Species:
Human
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
251
Content And Storage:
-20°C or -80°C if preferred
Isotype:
IgG1
Antigen: SLC7A11
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.03% Proclin 300, pH 7.4
Gene Accession No.: Q9UPY5
Gene Symbols: SLC7A11
Immunogen: Recombinant Human SLC7A11 protein
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Neutralization
Clone: 23H6
Conjugate: Unconjugated
Gene: SLC7A11
Gene Alias: 9930009M05Rik, AI451155, Amino acid transport system xc-, calcium channel blocker resistance protein CCBR1, CCBR1, cysteine/glutamate transporter, cystine/glutamate transporter, SLC7A11, sodium independent anionic amino acid transport system, solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11, solute carrier family 7 (cationic amino acid transporter, y+ system), member 11, solute carrier family 7 member 11, solute carrier family 7, (cationic amino acid transporter, y+ system) member 11, sut, xCT
Host Species: Human
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 23657
Content And Storage: -20°C or -80°C if preferred
Isotype: IgG1
Antigen:
SLC7A11
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.03% Proclin 300, pH 7.4
Gene Accession No.:
Q9UPY5
Gene Symbols:
SLC7A11
Immunogen:
Recombinant Human SLC7A11 protein
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Neutralization
Clone:
23H6
Conjugate:
Unconjugated
Gene:
SLC7A11
Gene Alias:
9930009M05Rik, AI451155, Amino acid transport system xc-, calcium channel blocker resistance protein CCBR1, CCBR1, cysteine/glutamate transporter, cystine/glutamate transporter, SLC7A11, sodium independent anionic amino acid transport system, solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11, solute carrier family 7 (cationic amino acid transporter, y+ system), member 11, solute carrier family 7 member 11, solute carrier family 7, (cationic amino acid transporter, y+ system) member 11, sut, xCT
Host Species:
Human
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23657
Content And Storage:
-20°C or -80°C if preferred
Isotype:
IgG1
Antigen: TUBB1
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.03% Proclin 300, pH 7.4
Gene Accession No.: Q9H4B7
Gene Symbols: TUBB1
Immunogen: Recombinant Human TUBB1 protein
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Clone: 16E2
Conjugate: Unconjugated
Gene: TUBB1
Gene Alias: 2810484G07Rik, M(beta)1, tbb1, TUBB1, tubulin beta, tubulin beta 1 class VI, tubulin beta-1 chain, tubulin, beta 1 class VI
Host Species: Mouse
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 81027
Content And Storage: -20°C or -80°C if preferred
Isotype: IgG
Antigen:
TUBB1
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.03% Proclin 300, pH 7.4
Gene Accession No.:
Q9H4B7
Gene Symbols:
TUBB1
Immunogen:
Recombinant Human TUBB1 protein
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Clone:
16E2
Conjugate:
Unconjugated
Gene:
TUBB1
Gene Alias:
2810484G07Rik, M(beta)1, tbb1, TUBB1, tubulin beta, tubulin beta 1 class VI, tubulin beta-1 chain, tubulin, beta 1 class VI
Host Species:
Mouse
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
81027
Content And Storage:
-20°C or -80°C if preferred
Isotype:
IgG