FEMA550314
Phospho-STAT3 (Tyr705) Recombinant Rabbit Monoclonal Antibody (HL1464), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA550314-Each-of-1 | In Stock | ₹ 39,785.40 |
FEMA550314 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 39,785.40
GST (18%): ₹ 7,161.372
Total Price: ₹ 46,946.772
Antigen
Phospho-STAT3 (Tyr705)
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
P40763, P52631
Gene Symbols
STAT3
Immunogen
Carrier-protein conjugated synthetic peptide surrounding phospho Tyr705 of human STAT3. The exact sequence is proprietary.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Rat
Form
Liquid
Applications
Western Blot
Clone
HL1464
Conjugate
Unconjugated
Gene
STAT3
Gene Alias
1110034C02Rik, acute phase response factor, acute-phase response factor, ADMIO, ADMIO1, APRF, AW109958, DNA-binding protein APRF, FLJ20882, HIES, MGC16063, signal transducer and activator of transcription 3, signal transducer and activator of transcription 3 (acute-phase response factor), signal transducer, activator of transcription, acute-phase response factor, signal transduction and activation of transcription 3, STAT, STAT3, STAT-3, stat3 protein, STAT3b1, STAT3b2, transcription factor, Unknown (protein for MGC:128731), wu:fc15d02, wu:fl59g06, z-Stat3
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
25125, 6774
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG
Related Products
Description
- STAT3 belongs to the family of STAT (signal transducers and activators of transcription) proteins which are phosphorylated by receptor associated kinases, translocate to the nucleus, and act as transcription factors in response to cytokines and growth factors
- Coactivators such as CREB-binding protein are required for the transcriptional activation by STAT3
- STAT3 can also be activated by Interferon-alpha, Interferon-gamma, EGF, PDGF and IL6
- Phosphorylation on tyrosine 705 by JAK1 and JAK2 is essential for STAT3 dimer formation, nuclear translocation, and DNA binding activity
- In humans, the STAT3 gene is located on the q arm of chromosome 17
- STAT3 has been shown to be activated by IFN-alpha but not IFN-beta
- The transcription factors associated with STAT3 are c-Jun and cyclic AMP-responsive enhancer binding protein (CREB)
- STAT3 mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis
- The small GTPase Rac1 has been shown to bind and regulate the activity of STAT3 while the PIAS3 protein is a specific inhibitor of STAT3
- Three alternatively spliced transcript variants encoding distinct isoforms of STAT3 have been described
- Deletion of the STAT3 gene in knock-out mice was lethal at the early embryonic stage.
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Antigen: Phospho-STAT3 (Tyr705)
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: P40763, P52631
Gene Symbols: STAT3
Immunogen: Carrier-protein conjugated synthetic peptide surrounding phospho Tyr705 of human STAT3. The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Rat
Form: Liquid
Applications: Western Blot
Clone: HL1464
Conjugate: Unconjugated
Gene: STAT3
Gene Alias: 1110034C02Rik, acute phase response factor, acute-phase response factor, ADMIO, ADMIO1, APRF, AW109958, DNA-binding protein APRF, FLJ20882, HIES, MGC16063, signal transducer and activator of transcription 3, signal transducer and activator of transcription 3 (acute-phase response factor), signal transducer, activator of transcription, acute-phase response factor, signal transduction and activation of transcription 3, STAT, STAT3, STAT-3, stat3 protein, STAT3b1, STAT3b2, transcription factor, Unknown (protein for MGC:128731), wu:fc15d02, wu:fl59g06, z-Stat3
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 25125, 6774
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG
Antigen:
Phospho-STAT3 (Tyr705)
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
P40763, P52631
Gene Symbols:
STAT3
Immunogen:
Carrier-protein conjugated synthetic peptide surrounding phospho Tyr705 of human STAT3. The exact sequence is proprietary.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Rat
Form:
Liquid
Applications:
Western Blot
Clone:
HL1464
Conjugate:
Unconjugated
Gene:
STAT3
Gene Alias:
1110034C02Rik, acute phase response factor, acute-phase response factor, ADMIO, ADMIO1, APRF, AW109958, DNA-binding protein APRF, FLJ20882, HIES, MGC16063, signal transducer and activator of transcription 3, signal transducer and activator of transcription 3 (acute-phase response factor), signal transducer, activator of transcription, acute-phase response factor, signal transduction and activation of transcription 3, STAT, STAT3, STAT-3, stat3 protein, STAT3b1, STAT3b2, transcription factor, Unknown (protein for MGC:128731), wu:fc15d02, wu:fl59g06, z-Stat3
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
25125, 6774
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG
Antigen: MC1R
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: Q01726, Q01727
Gene Symbols: Mc1r
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human MC1 Receptor. The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: HL1471
Conjugate: Unconjugated
Gene: Mc1r
Gene Alias: alpha melanocyte stimulating hormone receptor, CMM5, e, extension recessive yellow, MC1 receptor, MC1R, MC1-R, melanocortin 1 receptor, melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor), melanocortin receptor 1, melanocortin-1 receptor, melanocyte-stimulating hormone receptor, melanotropin receptor, MSHR, MSH-R, Mshra, SHEP2, Tob, tobacco darkening
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 102552838, 17199, 4157
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG
Antigen:
MC1R
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
Q01726, Q01727
Gene Symbols:
Mc1r
Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human MC1 Receptor. The exact sequence is proprietary.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
HL1471
Conjugate:
Unconjugated
Gene:
Mc1r
Gene Alias:
alpha melanocyte stimulating hormone receptor, CMM5, e, extension recessive yellow, MC1 receptor, MC1R, MC1-R, melanocortin 1 receptor, melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor), melanocortin receptor 1, melanocortin-1 receptor, melanocyte-stimulating hormone receptor, melanotropin receptor, MSHR, MSH-R, Mshra, SHEP2, Tob, tobacco darkening
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
102552838, 17199, 4157
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG
Antigen: Phospho-CDK2 (Tyr15)
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: P23573, P24941, P97377, Q63699
Gene Symbols: CDK2
Immunogen: Carrier-protein conjugated synthetic peptide corresponding to residues around human CDK2 (phospho Tyr15). The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Drosophila, Human, Mouse, Rat
Form: Liquid
Applications: ELISA, Western Blot
Clone: HL1474
Conjugate: Unconjugated
Gene: CDK2
Gene Alias: A630093N05Rik, CDC28, CDC2A, cdc2-related protein kinase, CDK1, CDK2, CDKN2, Cell division protein kinase 2, cyclin dependent kinase 2, cyclin dependent kinase 2-alpha, cyclin-dependent kinase 2, EC 2.7.11.22, EC 2.7.11.23, kinase Cdc2, MPF, p33 protein kinase, p33(CDK2), p33CDK2, p34 protein kinase
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 1017, 12566, 362817, 42453
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG
Antigen:
Phospho-CDK2 (Tyr15)
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
P23573, P24941, P97377, Q63699
Gene Symbols:
CDK2
Immunogen:
Carrier-protein conjugated synthetic peptide corresponding to residues around human CDK2 (phospho Tyr15). The exact sequence is proprietary.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Drosophila, Human, Mouse, Rat
Form:
Liquid
Applications:
ELISA, Western Blot
Clone:
HL1474
Conjugate:
Unconjugated
Gene:
CDK2
Gene Alias:
A630093N05Rik, CDC28, CDC2A, cdc2-related protein kinase, CDK1, CDK2, CDKN2, Cell division protein kinase 2, cyclin dependent kinase 2, cyclin dependent kinase 2-alpha, cyclin-dependent kinase 2, EC 2.7.11.22, EC 2.7.11.23, kinase Cdc2, MPF, p33 protein kinase, p33(CDK2), p33CDK2, p34 protein kinase
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
1017, 12566, 362817, 42453
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG
Antigen: SOD2
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: P04179
Gene Symbols: SOD2
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human SOD2. The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Zebrafish
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: HL1483
Conjugate: Unconjugated
Gene: SOD2
Gene Alias: I79_015272, indophenoloxidase B, IPO B, IPOB, IPO-B, manganese SOD, manganese superoxide dismutase, manganese-containing superoxide dismutase, mangano-superoxide dismutase, manganous superoxide dismutase, mitochondrial superoxide dismutase 2, Mn superoxide dismutase, MNSOD, Mn-SOD, MVCD6, similar to manganous superoxide dismutase, Sod2, Sod-2, sod2.L, sodMt, Superoxide dimutase 2, mitochondrial, superoxide dismutase, superoxide dismutase (Mn type), superoxide dismutase [Mn], mitochondrial, superoxide dismutase 2, superoxide dismutase 2 L homeolog, superoxide dismutase 2, mitochondrial, superoxide dismutase 2, mitochondrial L homeolog
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 335799, 6648
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG
Antigen:
SOD2
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
P04179
Gene Symbols:
SOD2
Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human SOD2. The exact sequence is proprietary.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Zebrafish
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
HL1483
Conjugate:
Unconjugated
Gene:
SOD2
Gene Alias:
I79_015272, indophenoloxidase B, IPO B, IPOB, IPO-B, manganese SOD, manganese superoxide dismutase, manganese-containing superoxide dismutase, mangano-superoxide dismutase, manganous superoxide dismutase, mitochondrial superoxide dismutase 2, Mn superoxide dismutase, MNSOD, Mn-SOD, MVCD6, similar to manganous superoxide dismutase, Sod2, Sod-2, sod2.L, sodMt, Superoxide dimutase 2, mitochondrial, superoxide dismutase, superoxide dismutase (Mn type), superoxide dismutase [Mn], mitochondrial, superoxide dismutase 2, superoxide dismutase 2 L homeolog, superoxide dismutase 2, mitochondrial, superoxide dismutase 2, mitochondrial L homeolog
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
335799, 6648
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG