FEMA550385

TPL2 Recombinant Rabbit Monoclonal Antibody (HL2118), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA550385-Each-of-1 In Stock ₹ 39,785.40

FEMA550385 - Each of 1

₹ 39,785.40

In Stock

Quantity

1

Base Price: ₹ 39,785.40

GST (18%): ₹ 7,161.372

Total Price: ₹ 46,946.772

Antigen

TPL2

Classification

Recombinant Monoclonal

Concentration

2 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

P41279, Q07174

Gene Symbols

MAP3K8

Immunogen

Recombinant fragmemt of human MAP3K8.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

HL2118

Conjugate

Unconjugated

Gene

MAP3K8

Gene Alias

augmented in rheumatoid arthritis 2, AURA2, Cancer Osaka thyroid oncogene, cancer Osaka thyroid, oncogene, CCOT, c-COT, COT, cot (cancer Osaka thyroid) oncogene, COT proto-oncogene serine/threonine-protein kinase, Cot/Tpl2, D17TPL2, EC 1.14.16.2, Est, Estf, Ewing sarcoma transformant, FLJ10486, M3K8, MAP3K 8, Map3k8, MEKK8, mitogen activated protein kinase kinase kinase 8, mitogen-activated protein kinase kinase kinase 8, Protein kinase cot, Proto-oncogene c-Cot, proto-oncogene serine/threoine protein kinase, serine/threonine kinase (Tpl-2), serine/threonine-protein kinase cot, TH isoform 3, TH isoform a, TH-4, TPL 2, Tpl2, TPL-2, Tumor progression locus 2, TY3H, TYH

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

1326, 26410

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG

Related Products

Img

Thermo Scientific

FEMA550456

--

Img

Thermo Scientific

FEMA550448

--

Img

Thermo Scientific

FEMA549885

--

Img

Thermo Scientific

FEMA550552

--

Img

Thermo Scientific

FEMA549998

--

Img

Thermo Scientific

FEMA550455

--

Img

Thermo Scientific

FEMA550789

--

Img

Thermo Scientific

FEMA550472

--

Description

  • MAP3K8 (COT) is a serine/threonine kinase which can activate both the MAP and JNK kinase pathways and plays a role in the cell cycle
  • Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase (MAPKKK or MEKK)
  • MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK
  • The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells
  • MEKK8 is able to activate NF-kappa-B 1 by stimulating proteasome-mediated proteolysis of NF-kappa-B 1/p105
  • This cytoplasmic protein is expressed in several normal tissues and human tumor-derived cell lines
  • The 58 kDa form is activated specifically during the S and G2/M phases of the cell cycle
  • The longer form undergoes phosphorylation on Ser residues mainly, and the shorter form on both Ser and Thr residues.

Compare Similar Items

Show Difference

Img

Thermo Scientific

FEMA550385

--


Antigen:
TPL2

Classification:
Recombinant Monoclonal

Concentration:
2 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P41279, Q07174

Gene Symbols:
MAP3K8

Immunogen:
Recombinant fragmemt of human MAP3K8.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
HL2118

Conjugate:
Unconjugated

Gene:
MAP3K8

Gene Alias:
augmented in rheumatoid arthritis 2, AURA2, Cancer Osaka thyroid oncogene, cancer Osaka thyroid, oncogene, CCOT, c-COT, COT, cot (cancer Osaka thyroid) oncogene, COT proto-oncogene serine/threonine-protein kinase, Cot/Tpl2, D17TPL2, EC 1.14.16.2, Est, Estf, Ewing sarcoma transformant, FLJ10486, M3K8, MAP3K 8, Map3k8, MEKK8, mitogen activated protein kinase kinase kinase 8, mitogen-activated protein kinase kinase kinase 8, Protein kinase cot, Proto-oncogene c-Cot, proto-oncogene serine/threoine protein kinase, serine/threonine kinase (Tpl-2), serine/threonine-protein kinase cot, TH isoform 3, TH isoform a, TH-4, TPL 2, Tpl2, TPL-2, Tumor progression locus 2, TY3H, TYH

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1326, 26410

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG

Img

Thermo Scientific

FEMA550388

--


Antigen:
FDPS

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P05369, P14324, Q920E5

Gene Symbols:
FDPS

Immunogen:
Recombinant fragment of human FDPS.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
HL2123

Conjugate:
Unconjugated

Gene:
FDPS

Gene Alias:
(2E,6E)-farnesyl diphosphate synthase, 6030492I17Rik, Ac2-125, AI256750, cholesterol-regulated 39 kDa protein, CR 39, dimethylallyltranstransferase, Farnesyl diphosphate synthase, farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase), farnesyl diphosphate synthetase, farnesyl pyrophosphate synthase, farnesyl pyrophosphate synthetase, farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase, Fdps, Fdpsl1, FPP synthase, FPP synthetase, FPPS, FPS, geranyltranstransferase, KIAA1293, mKIAA1293, POROK9, testis-specific farnesyl pyrophosphate synthetase

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
110196, 2224, 83791

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG

Img

Thermo Scientific

FEMA550389

--


Antigen:
GluD1/GluD2

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P00367, P10860, P26443, P49448

Gene Symbols:
GLUD1, GLUD2

Immunogen:
Recombinant fragmemt of human GLUD1+GLUD2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
HL2124

Conjugate:
Unconjugated

Gene:
GLUD2

Gene Alias:
Ac2-281, AI118167, epididymis tissue sperm binding protein Li 18mP, GDH, GDH 1, GDH 2, GDH1, GDH2, Gdh-X, Glud, Glud1, GLUD2, Gludeha, Gludl, GLUDP1, glutamate dehydrogenase (NAD(P)+), glutamate dehydrogenase 1, glutamate dehydrogenase 1, mitochondrial, glutamate dehydrogenase 2, glutamate dehydrogenase 2, mitochondrial, glutamate dehydrogenase pseudogene 1, memory-related gene 2 protein, MRG-2, testicular secretory protein Li 14

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
14661, 24399, 2746, 2747

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG

Img

Thermo Scientific

FEMA550392

--


Antigen:
Influenza A H1N1 HA (A/California/07/2009)

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Recombinant fragment of Influenza A virus NS1 (nonstructural protein).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Virus

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Clone:
HL2130

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
flu hemagglutinin, H1N1 HA, H1N1 hemagglutinin, Influenza H1N1, influenza hemagglutinin

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG