FEMA550545

IFIT3 Recombinant Rabbit Monoclonal Antibody (HL2469), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA550545-Each-of-1 In Stock ₹ 39,785.40

FEMA550545 - Each of 1

₹ 39,785.40

In Stock

Quantity

1

Base Price: ₹ 39,785.40

GST (18%): ₹ 7,161.372

Total Price: ₹ 46,946.772

Antigen

IFIT3

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

O14879

Gene Symbols

IFIT3

Immunogen

Recombinant fragment of human IFIT3.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

HL2469

Conjugate

Unconjugated

Gene

IFIT3

Gene Alias

cig41, CIG49, CIG-49, Garg49, GARG-49, Glucocorticoid-attenuated response gene 49 protein, Ifi49, IFI60, IFI-60K, IFIT3, IFIT-3, IFIT4, IFIT-4, interferon induced protein with tetratricopeptide repeats 3, interferon-induced 60 kDa protein, Interferon-induced protein with tetratricopeptide repeats 3, interferon-induced protein with tetratricopeptide repeats 4, interferon-stimulated protein 60, IRG2, Isg49, ISG60, ISG-60, P49, P60, retinoic acid-induced gene G protein, RIG-G, RP11-149I23.4

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

3437

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG

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Description

  • IFN-induced antiviral protein which acts as an inhibitor of cellular as well as viral processes, cell migration, proliferation, signaling, and viral replication
  • Enhances MAVS-mediated host antiviral responses by serving as an adapter bridging TBK1 to MAVS which leads to the activation of TBK1 and phosphorylation of IRF3 and phosphorylated IRF3 translocates into nucleus to promote antiviral gene transcription
  • Exhibits an antiproliferative activity via the up-regulation of cell cycle negative regulators CDKN1A/p21 and CDKN1B/p27
  • Normally, CDKN1B/p27 turnover is regulated by COPS5, which binds CDKN1B/p27 in the nucleus and exports it to the cytoplasm for ubiquitin-dependent degradation
  • IFIT3 sequesters COPS5 in the cytoplasm, thereby increasing nuclear CDKN1B/p27 protein levels
  • Upregulates CDKN1A/p21 by downregulating MYC, a repressor of CDKN1A/p21
  • Can negatively regulate the apoptotic effects of IFIT2.

Compare Similar Items

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Img

Thermo Scientific

FEMA550545

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Antigen:
IFIT3

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
O14879

Gene Symbols:
IFIT3

Immunogen:
Recombinant fragment of human IFIT3.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
HL2469

Conjugate:
Unconjugated

Gene:
IFIT3

Gene Alias:
cig41, CIG49, CIG-49, Garg49, GARG-49, Glucocorticoid-attenuated response gene 49 protein, Ifi49, IFI60, IFI-60K, IFIT3, IFIT-3, IFIT4, IFIT-4, interferon induced protein with tetratricopeptide repeats 3, interferon-induced 60 kDa protein, Interferon-induced protein with tetratricopeptide repeats 3, interferon-induced protein with tetratricopeptide repeats 4, interferon-stimulated protein 60, IRG2, Isg49, ISG60, ISG-60, P49, P60, retinoic acid-induced gene G protein, RIG-G, RP11-149I23.4

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3437

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG

Img

Thermo Scientific

FEMA550546

--


Antigen:
Chikungunya Virus E3

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Full length Chikungunya virus E3 recombinant protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Virus

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Clone:
HL2476

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
Chikungunya

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG

Img

Thermo Scientific

FEMA550547

--


Antigen:
Chikungunya Virus NSP3

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Recombinant fragment of Chikungunya virus nsP3.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Virus

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
HL2479

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
CHIKV NSP3, NsP3 protein

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG

Img

Thermo Scientific

FEMA550549

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Antigen:
CCR4

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P51679, P51680

Gene Symbols:
Ccr4

Immunogen:
Synthetic peptide of human CCR4.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
HL2481

Conjugate:
Unconjugated

Gene:
Ccr4

Gene Alias:
C-C chemokine receptor 4, C-C chemokine receptor type 4, C-C CKR-4, C-C motif chemokine receptor 4, CC-CKR-4, Ccr4, CCR-4, CD194, chemokine (C-C motif) receptor 4, chemokine (C-C) receptor 4, CHEMR1, ChemR13, CKR4, Cmkbr4, fusin, HGCN:14099, K5-5, LESTR, leukocyte-expressed seven-transmembrane-domain receptor, MGC88293, Sdf1r

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1233, 12773, 171054

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG