FEMA550574

CD35 Monoclonal Antibody (A4G1), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA550574-Each-of-1 In Stock ₹ 40,127.64

FEMA550574 - Each of 1

₹ 40,127.64

In Stock

Quantity

1

Base Price: ₹ 40,127.64

GST (18%): ₹ 7,222.975

Total Price: ₹ 47,350.615

Antigen

CD35

Classification

Monoclonal

Concentration

2 mg/mL

Formulation

TBS with 0.1% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

P17927

Gene Symbols

CR1

Immunogen

Synthetic peptide within C-terminal human CD35 aa 1990-2039/2039.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

A4G1

Conjugate

Unconjugated

Gene

CR1

Gene Alias

C3 binding protein, C3b/C4b receptor, C3-binding protein, C3BR, C4BR, CD35, CD35 antigen, complement component (3b/4b) receptor 1 (Knops blood group), Complement Component (3b/4b) receptor 1 including Knops blood group system, complement component 3b/4b receptor 1 (Knops blood group), complement receptor type 1, CR1, KN, Knops blood group antigen

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

1378

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG1

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Description

  • Positive control: TF-1 cell lysates, human spleen tissue, human tonsil tissue
  • Predicted band size: 224 kDa Subcellular Location: Membrane
  • CD35 (CR1, Complement Receptor 1) is a cell membrane-bound, monomeric glycoprotein and its primary function is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules
  • CD35 protein mediates cellular binding to particles and immune complexes that have activated complement
  • The CD35 complex is four different allotypes (C,A,B,D) C is 160 kDa; A is 190 kDa; B is 220 kDa and D is 250 kDa
  • CD35 is involved in the processing of immune complexes, promoting of binding and phagocytosis of C3b complexes and inhibition of complement activation
  • CD35 is on neutrophils, eosinophils, monocytes, B-cells, some NK-cells, erythrocytes, myeloid leukemias, follicular dendritic reticulum cells and is negative on basophils
  • Decreases in expression of CD35 protein and/or mutations in its gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus and sarcoidosis
  • Mutations in the CD35 gene have also been associated with a reduction in Plasmodium falciparum rosetting, conferring protection against severe malaria
  • Alternate allele-specific splice variants encoding different isoforms of CD35 have been characterized
  • An additional secreted form of CD35 have also been described but has not been fully characterized.

Compare Similar Items

Show Difference

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Thermo Scientific

FEMA550574

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Antigen:
CD35

Classification:
Monoclonal

Concentration:
2 mg/mL

Formulation:
TBS with 0.1% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P17927

Gene Symbols:
CR1

Immunogen:
Synthetic peptide within C-terminal human CD35 aa 1990-2039/2039.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
A4G1

Conjugate:
Unconjugated

Gene:
CR1

Gene Alias:
C3 binding protein, C3b/C4b receptor, C3-binding protein, C3BR, C4BR, CD35, CD35 antigen, complement component (3b/4b) receptor 1 (Knops blood group), Complement Component (3b/4b) receptor 1 including Knops blood group system, complement component 3b/4b receptor 1 (Knops blood group), complement receptor type 1, CR1, KN, Knops blood group antigen

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
1378

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1

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Antigen:
Ebola Virus GP

Classification:
Monoclonal

Concentration:
2 mg/mL

Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
__

Gene Symbols:
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Immunogen:
Synthetic peptide within Zaire Ebola virus Envelope glycoprotein aa 400-450/676.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Virus

Form:
Liquid

Applications:
ELISA

Clone:
A1-A6

Conjugate:
Unconjugated

Gene:
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Gene Alias:
EVD

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2b

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Antigen:
MUM1

Classification:
Monoclonal

Concentration:
2 mg/mL

Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q2TAK8

Gene Symbols:
MUM1

Immunogen:
Synthetic peptide within human MUM1 aa 402-451/451.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
A7D1

Conjugate:
Unconjugated

Gene:
MUM1

Gene Alias:
2610019J09, 9430059D04Rik, EXPAND1, FLJ14868, FLJ22283, HSPC211, melanoma associated antigen (mutated) 1, melanoma ubiquitous mutated protein, MGC131891, MGC163315, Mum1, MUM-1, Mutated melanoma-associated antigen 1, protein expandere, PWWP domain-containing DNA repair factor 3A, PWWP domain-containing protein MUM1, Pwwp3a, UBE-1C2

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
84939

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1

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Antigen:
MUM1

Classification:
Monoclonal

Concentration:
2 mg/mL

Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q2TAK8

Gene Symbols:
MUM1

Immunogen:
Synthetic peptide within human MUM1 aa 402-451/451.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Clone:
A7C12

Conjugate:
Unconjugated

Gene:
MUM1

Gene Alias:
2610019J09, 9430059D04Rik, EXPAND1, FLJ14868, FLJ22283, HSPC211, melanoma associated antigen (mutated) 1, melanoma ubiquitous mutated protein, MGC131891, MGC163315, Mum1, MUM-1, Mutated melanoma-associated antigen 1, protein expandere, PWWP domain-containing DNA repair factor 3A, PWWP domain-containing protein MUM1, Pwwp3a, UBE-1C2

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
84939

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1