FEMA550610

CD204 Monoclonal Antibody (A8G2), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA550610-Each-of-1 In Stock ₹ 40,127.64

FEMA550610 - Each of 1

₹ 40,127.64

In Stock

Quantity

1

Base Price: ₹ 40,127.64

GST (18%): ₹ 7,222.975

Total Price: ₹ 47,350.615

Antigen

CD204

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

P21757

Gene Symbols

MSR1

Immunogen

Recombinant protein within Human CD204 aa 51-250/451.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

A8G2

Conjugate

Unconjugated

Gene

MSR1

Gene Alias

bovine scavenger receptor type II, CD204, Macrophage acetylated LDL receptor I and II, macrophage scavenger receptor 1, macrophage scavenger receptor type III, macrophage scavenger receptor types I and II, MRS-A, MSR, Msr1, MSR-A, phSR1, phSR2, RGD1564316, SCARA1, Scavenger receptor class A member 1, scavenger receptor class A, member 1, scavenger receptor type A, scavenger receptor type I, Scvr, SRA, SR-A, SR-AI, SR-AI/II, SR-AII

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

4481

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG1

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Description

  • Positive control: THP-1 cell lysate treated with 80nM PMA for 72 hours, human liver tissue
  • Predicted band size: 50 kDa Subcellular Location: Membrane
  • CD204 gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene
  • These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense
  • The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs)
  • The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms
  • It has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis
  • The isoform type 3 can inhibit the function of isoforms type 1 and type 2 when co-expressed, indicating a dominant negative effect and suggesting a mechanism for regulation of scavenger receptor activity in macrophages
  • Diseases associated with MSR1 include Barrett Esophagus and Prostate Cancer.

Compare Similar Items

Show Difference

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Thermo Scientific

FEMA550610

--


Antigen:
CD204

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P21757

Gene Symbols:
MSR1

Immunogen:
Recombinant protein within Human CD204 aa 51-250/451.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
A8G2

Conjugate:
Unconjugated

Gene:
MSR1

Gene Alias:
bovine scavenger receptor type II, CD204, Macrophage acetylated LDL receptor I and II, macrophage scavenger receptor 1, macrophage scavenger receptor type III, macrophage scavenger receptor types I and II, MRS-A, MSR, Msr1, MSR-A, phSR1, phSR2, RGD1564316, SCARA1, Scavenger receptor class A member 1, scavenger receptor class A, member 1, scavenger receptor type A, scavenger receptor type I, Scvr, SRA, SR-A, SR-AI, SR-AI/II, SR-AII

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
4481

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1

Img

Thermo Scientific

FEMA550614

--


Antigen:
NAPSA

Classification:
Monoclonal

Concentration:
2 mg/mL

Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
O96009

Gene Symbols:
NAPSA

Immunogen:
Recombinant protein within human NAPSIN A aa 51-200/420.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Clone:
A9B12

Conjugate:
Unconjugated

Gene:
NAPSA

Gene Alias:
asp 4, ASP4, Aspartyl protease 4, KAP, Kdap, KDAP-1, kidney-derived aspartic protease-like protein, Nap, NAP1, NAPA, Napsa, napsin A aspartic peptidase, napsin-1, Napsin-A, pronapsin, pronapsin A, SNAPA, TA01/TA02

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
9476

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2a

Img

Thermo Scientific

FEMA550615

--


Antigen:
NAPSA

Classification:
Monoclonal

Concentration:
2 mg/mL

Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
O96009

Gene Symbols:
NAPSA

Immunogen:
Recombinant protein within human NAPSIN A aa 51-200/420.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin)

Clone:
A9C1

Conjugate:
Unconjugated

Gene:
NAPSA

Gene Alias:
asp 4, ASP4, Aspartyl protease 4, KAP, Kdap, KDAP-1, kidney-derived aspartic protease-like protein, Nap, NAP1, NAPA, Napsa, napsin A aspartic peptidase, napsin-1, Napsin-A, pronapsin, pronapsin A, SNAPA, TA01/TA02

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
9476

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1

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FEMA550617

--


Antigen:
Kappa Light Chain

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P01601, P01602, P01834, P0DOX7

Gene Symbols:
IGK, IGKC, IGKV1-5, IGKV1D-16

Immunogen:
Recombinant full protein within human IGKC aa 1-107/107.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
A8H10

Conjugate:
Unconjugated

Gene:
IGKV1-5

Gene Alias:
D4Mit8, HCAK1, ig kappa chain c region, Igk, Igk@, Igkc, Igk-C, IGKCD, IGKV, IGKV15, IGKV1-5, Immunoglobulin K, immunoglobulin kappa chain complex, immunoglobulin kappa constant, immunoglobulin kappa light chain, immunoglobulin kappa locus, immunoglobulin kappa variable 1-5, kappa, Kappa LC, Km, L12, L12a, LOC500183, similar to NGF-binding Ig light chain, V1

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
28299, 28901, 3514, 50802

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1