GRP78 Recombinant Mouse Monoclonal Antibody (C9-9-R), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA550635-Each-of-1 | In Stock | ₹ 40,641.00 |
FEMA550635 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 40,641.00
GST (18%): ₹ 7,315.38
Total Price: ₹ 47,956.38
Antigen
GRP78
Classification
Recombinant Monoclonal
Concentration
2 mg/mL
Formulation
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
P06761, P11021, P20029
Gene Symbols
Hspa5
Immunogen
Recombinant protein within human GRP78 BiP aa 100-400/654.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat, Zebrafish
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
C9-9-R
Conjugate
Unconjugated
Gene
Hspa5
Gene Alias
78 kDa glucose-regulated protein, 78 kDa glucose-regulated protein homolog, 78-kD glucose-regulated protein precursor, AL022860, AU019543, baffled, Binding-immunoglobulin protein, bip, BiP protein, BiP/Grp78, cb865, D2Wsu141e, D2Wsu17e, Endoplasmic reticulum chaperone BiP, endoplasmic reticulum chaperone BiP, 78 kDa glucose-regulated protein, endoplasmic reticulum lumenal Ca(2+)-binding protein grp78, epididymis secretory sperm binding protein Li 89n, fb60h09, fi36d04, FLJ26106, glucose regulated protein, 78 kDa, glucose-regulated protein, glucose-regulated protein, 78kDa, GRP 78, grp78, GRP-78, heat shock 70 kDa protein 5, heat shock 70 kDa protein 5a, heat shock 70kD protein 5, heat shock 70kD protein 5 (glucose-regulated protein, 78kD), heat shock 70kDa protein 5, heat shock 70kDa protein 5 (glucose-regulated protein), heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa), heat shock protein 5, heat shock protein 70 family protein 5, heat shock protein family A (Hsp70) member 5, heat shock protein family A (Hsp70) member 5 L homeolog, heat shock protein family A member 5, heavy-chain binding protein BiP, HEL-S-89n, Hsce70, hsp70, Hsp70 family ATPase KAR2, HSP70 family protein 5, HSPA 5, HSPA5, hspa5.L, hspa5a, I79_019946, immunoglobulin binding protein, immunoglobulin heavy chain-binding protein, Immunoglobulin heavy chain-binding protein homolog, J1248, KAR2, mBiP, MIF2, Sez7, SEZ-7, SSD1, Steroidogenesis-activator polypeptide, wu:fb60h09, wu:fi36d04, XAP-1, XAP-1 antigen, XELAEV_180384511mg, YJL034W, zgc:55994, zgc:77606
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
14828, 25617, 3309, 378848
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG1
Related Products
Description
- Positive control: HepG2 cell lysate, MCF-7 cell lysate, RAW264.7 cell lysate, F9 cell lysate, NIH/3T3 cell lysate, PC-12 cell lysate, PMVEC cell lysate, mouse brain tissue lysate, rat brain tissue, mouse small intestine tissue, Hela
- Predicted band size: 72 kDa Subcellular Location: Cytoplasm, endoplasmic reticulum lumen
- GRP78 is a 78 kDa glucose regulated protein that belongs to the family of heat shock proteins that include HSP70
- GRP78 is a resident protein of the endoplasmic reticulum (ER) and associates transiently with a variety of newly synthesized secretory and membrane proteins
- GRP78 may also interact with mutant and misfolded proteins, marking them for degradation
- The highly conserved sequence Lys-Asp-Glu-Leu (KDEL) is present at the C-terminus of GRP78 and other resident ER proteins including glucose regulated protein 94 (GRP94) and protein disulfide isomerase (PDI)
- The KDEL signal is recognized by the KDEL receptor and this interaction ensures recycling of escaped ER proteins back to the ER
- GRP78’s involvement in correct folding of proteins and degradation of misfolded proteins is via its interaction with DNAJC10, probably to facilitate the release of DNAJC10 from its substrate
- GRP78 is critical for maintenance of cell homeostasis and the prevention of apoptosis
- GRP78 protein levels have been shown to be a reliable biomarker of hypoglycemia and serves a neuroprotective function in neurons exposed to glutamate and oxidative stress
- GRP78 levels are reduced in the brains of Alzheimer's Disease patients, and decreased expression of GRP78 is found associated with missense mutations in the human presenilin-1 (PS1) gene
- Further, the induction of the GRP78 protein has been associated with the development of drug-resistance to antitumor drugs.
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Antigen: GRP78
Classification: Recombinant Monoclonal
Concentration: 2 mg/mL
Formulation: PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: P06761, P11021, P20029
Gene Symbols: Hspa5
Immunogen: Recombinant protein within human GRP78 BiP aa 100-400/654.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat, Zebrafish
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: C9-9-R
Conjugate: Unconjugated
Gene: Hspa5
Gene Alias: 78 kDa glucose-regulated protein, 78 kDa glucose-regulated protein homolog, 78-kD glucose-regulated protein precursor, AL022860, AU019543, baffled, Binding-immunoglobulin protein, bip, BiP protein, BiP/Grp78, cb865, D2Wsu141e, D2Wsu17e, Endoplasmic reticulum chaperone BiP, endoplasmic reticulum chaperone BiP, 78 kDa glucose-regulated protein, endoplasmic reticulum lumenal Ca(2+)-binding protein grp78, epididymis secretory sperm binding protein Li 89n, fb60h09, fi36d04, FLJ26106, glucose regulated protein, 78 kDa, glucose-regulated protein, glucose-regulated protein, 78kDa, GRP 78, grp78, GRP-78, heat shock 70 kDa protein 5, heat shock 70 kDa protein 5a, heat shock 70kD protein 5, heat shock 70kD protein 5 (glucose-regulated protein, 78kD), heat shock 70kDa protein 5, heat shock 70kDa protein 5 (glucose-regulated protein), heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa), heat shock protein 5, heat shock protein 70 family protein 5, heat shock protein family A (Hsp70) member 5, heat shock protein family A (Hsp70) member 5 L homeolog, heat shock protein family A member 5, heavy-chain binding protein BiP, HEL-S-89n, Hsce70, hsp70, Hsp70 family ATPase KAR2, HSP70 family protein 5, HSPA 5, HSPA5, hspa5.L, hspa5a, I79_019946, immunoglobulin binding protein, immunoglobulin heavy chain-binding protein, Immunoglobulin heavy chain-binding protein homolog, J1248, KAR2, mBiP, MIF2, Sez7, SEZ-7, SSD1, Steroidogenesis-activator polypeptide, wu:fb60h09, wu:fi36d04, XAP-1, XAP-1 antigen, XELAEV_180384511mg, YJL034W, zgc:55994, zgc:77606
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 14828, 25617, 3309, 378848
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG1
Antigen: 6x His Tag
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: __
Gene Symbols: __
Immunogen: Synthetic peptide HHHHHHGCGHHHHHH.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse, Tag
Form: Liquid
Applications: Immunoprecipitation, Western Blot
Clone: A5D1-R
Conjugate: Unconjugated
Gene: __
Gene Alias: 6His tag, 6X His, His Tag, Histidine Tag
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG1
Antigen: DYKDDDDK Tag
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: __
Gene Symbols: __
Immunogen: Synthetic peptide immune sequence is N-DYKDDDDK-C.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse, Tag
Form: Liquid
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
Clone: PS00-M2
Conjugate: Unconjugated
Gene: __
Gene Alias: DDDDK, DDDDK epitope tag, ECS epitope tag, ECS tag, FLAG, FLAG Tag
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG1
