FEMA550731
NPM1 Recombinant Rabbit Monoclonal Antibody (PD00-91), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA550731-Each-of-1 | In Stock | ₹ 40,641.00 |
FEMA550731 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 40,641.00
GST (18%): ₹ 7,315.38
Total Price: ₹ 47,956.38
Antigen
NPM1
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
P06748, P13084, Q61937
Gene Symbols
NPM1
Immunogen
Synthetic peptide within Human Nucleophosmin aa 1-100/294 (N terminal).
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Form
Liquid
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
PD00-91
Conjugate
Unconjugated
Gene
NPM1
Gene Alias
B23, B23 antibody, B23NP, MGC104254, mNPM antibody, mNPM1 antibody, NO38, NO38 antibody, Npm, npm1, npm1.L, Nucleolar phosphoprotein B23, nucleolar protein B23.1, nucleolar protein B23/No38, nucleolar protein NO38, Nucleophosmin, nucleophosmin (nucleolar phosphoprotein B23, numatrin), nucleophosmin (nucleolar phosphoprotein B23, numatrin) L homeolog, nucleophosmin 1, nucleophosmin/nucleoplasmin family, member 1, nucleoplasmin, numatrin, numatrin antibody, testicular tissue protein Li 128, unnamed protein product, XELAEV_18020022mg
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
18148, 25498, 4869
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG
Related Products
Description
- Positive control: Hela cell lysate, HepG2 cell lysate, A431 cell lysate, C2C12 cell lysate, RAW264.7 cell lysate, rat kidney tissue, mouse small intestine tissue, LOVO, Daudi, HL-60, human colon carcinoma tissue, human skin tissue
- Predicted band size: 33 kDa Subcellular Location: Nucleus, nucleolus, nucleoplasm, cytoplasm, cytoskeleton, microtubule organizing center, centrosome
- NPM1 (Nucleophosmin 1, B23, nutramin, NO38) is a ubiquitously expressed phosphoprotein involved in ribosome assembly/transport, cytoplasmic/nuclear trafficking, regulation of DNA polymerase alpha activity, centrosome duplication, and regulation of p53
- NPM1 continuously shuttles between the nucleus, cytoplasm, nucleolus and chaperoning core histones from the nucleus to the cytoplasm
- NPM1 has been shown to bind nucleic acid, prevent protein aggregation via its chaperon activities, protect enzymes during thermal denaturation, and facilitate renaturation of chemically denatured proteins
- In its cellular structure role, there is evidence suggesting NPM1 is associated with the centrosome, and is the substrate of CDK2/cyclin E during duplication of centrosomes (cellular division)
- Due to the NPM1 gene interaction with several tumor-associated chromosome translocations, NPM1 is thought to be a portion of several fusion proteins: NPM-ALK, NPM-RAR, and NPM-MLF1
- While it is not thought to be part of the transforming potential of these fusion proteins, NPM1 is believed to act as the interface for oligomerization and oncogenic conversion of these tumor promoting fusion proteins
- Further, NPM1 is also known to sequester the tumor suppressor RF in the nucleolus, protecting it from degradation until it is necessary
- Dysfunction of the NPM1 protein is associated with diseases such as acute myeloid leukemia and lymphomatoid papulosis.
Compare Similar Items
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Antigen: NPM1
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: P06748, P13084, Q61937
Gene Symbols: NPM1
Immunogen: Synthetic peptide within Human Nucleophosmin aa 1-100/294 (N terminal).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: PD00-91
Conjugate: Unconjugated
Gene: NPM1
Gene Alias: B23, B23 antibody, B23NP, MGC104254, mNPM antibody, mNPM1 antibody, NO38, NO38 antibody, Npm, npm1, npm1.L, Nucleolar phosphoprotein B23, nucleolar protein B23.1, nucleolar protein B23/No38, nucleolar protein NO38, Nucleophosmin, nucleophosmin (nucleolar phosphoprotein B23, numatrin), nucleophosmin (nucleolar phosphoprotein B23, numatrin) L homeolog, nucleophosmin 1, nucleophosmin/nucleoplasmin family, member 1, nucleoplasmin, numatrin, numatrin antibody, testicular tissue protein Li 128, unnamed protein product, XELAEV_18020022mg
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 18148, 25498, 4869
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG
Antigen:
NPM1
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
P06748, P13084, Q61937
Gene Symbols:
NPM1
Immunogen:
Synthetic peptide within Human Nucleophosmin aa 1-100/294 (N terminal).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
PD00-91
Conjugate:
Unconjugated
Gene:
NPM1
Gene Alias:
B23, B23 antibody, B23NP, MGC104254, mNPM antibody, mNPM1 antibody, NO38, NO38 antibody, Npm, npm1, npm1.L, Nucleolar phosphoprotein B23, nucleolar protein B23.1, nucleolar protein B23/No38, nucleolar protein NO38, Nucleophosmin, nucleophosmin (nucleolar phosphoprotein B23, numatrin), nucleophosmin (nucleolar phosphoprotein B23, numatrin) L homeolog, nucleophosmin 1, nucleophosmin/nucleoplasmin family, member 1, nucleoplasmin, numatrin, numatrin antibody, testicular tissue protein Li 128, unnamed protein product, XELAEV_18020022mg
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
18148, 25498, 4869
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG
Antigen: ErbB2 (HER-2)
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: P04626
Gene Symbols: ERBB2
Immunogen: Recombinant fragment within Human ErbB2/ HER2 aa 500-650/1255.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: PD00-99
Conjugate: Unconjugated
Gene: ERBB2
Gene Alias: avian erythroblastosis oncogene B 2, Avian erythroblastosis viral (v-erb-B2) oncogene homologue 2 (neuro/glioblastoma derived oncogene homolog), CD antigen CD340, CD340, c-erb B2/neu protein, c-erbB2, C-erbB-2, c-neu, epidermal growth factor receptor-related protein, erbb 2, ERBB2, erb-b2, Erbb-2, ErbB2 (pTyr1139), ErbB2 (pY1139), ErbB2 phospho Y1139, erb-b2 receptor tyrosine kinase 2, her 2, HER2, HER-2, HER-2/neu, herstatin, human epidermal growth factor receptor 2, Kiaa3023, metas, Metastatic lymph node gene 19 protein, mKIAA3023, MLN 19, MLN19, NEU, Neu oncogene, NEU proto-oncogene, neuro/glioblastoma derived oncogene homolog, neuroblastoma/glioblastoma derived oncogene homolog, NGL, p185erbB2, p185neu, phospho ErbB2, proto-oncogene c-ErbB-2, Proto-oncogene Neu, receptor tyrosine-protein kinase erbB-2, TKR1, Tyrosine kinase-type cell surface receptor HER2, v-erb-b2 avian erythroblastic leukemia viral oncogene 2, v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2, v-erb-b2 avian erythroblastic leukemia viral oncoprotein 2, v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog, v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 2064
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG
Antigen:
ErbB2 (HER-2)
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
P04626
Gene Symbols:
ERBB2
Immunogen:
Recombinant fragment within Human ErbB2/ HER2 aa 500-650/1255.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
PD00-99
Conjugate:
Unconjugated
Gene:
ERBB2
Gene Alias:
avian erythroblastosis oncogene B 2, Avian erythroblastosis viral (v-erb-B2) oncogene homologue 2 (neuro/glioblastoma derived oncogene homolog), CD antigen CD340, CD340, c-erb B2/neu protein, c-erbB2, C-erbB-2, c-neu, epidermal growth factor receptor-related protein, erbb 2, ERBB2, erb-b2, Erbb-2, ErbB2 (pTyr1139), ErbB2 (pY1139), ErbB2 phospho Y1139, erb-b2 receptor tyrosine kinase 2, her 2, HER2, HER-2, HER-2/neu, herstatin, human epidermal growth factor receptor 2, Kiaa3023, metas, Metastatic lymph node gene 19 protein, mKIAA3023, MLN 19, MLN19, NEU, Neu oncogene, NEU proto-oncogene, neuro/glioblastoma derived oncogene homolog, neuroblastoma/glioblastoma derived oncogene homolog, NGL, p185erbB2, p185neu, phospho ErbB2, proto-oncogene c-ErbB-2, Proto-oncogene Neu, receptor tyrosine-protein kinase erbB-2, TKR1, Tyrosine kinase-type cell surface receptor HER2, v-erb-b2 avian erythroblastic leukemia viral oncogene 2, v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2, v-erb-b2 avian erythroblastic leukemia viral oncoprotein 2, v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog, v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
2064
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG
Antigen: p53
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: P04637
Gene Symbols: Tp53
Immunogen: Recombinant full length protein within Human p53 aa 1-393/393.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Immunohistochemistry (Paraffin)
Clone: PD01-32
Conjugate: Unconjugated
Gene: Tp53
Gene Alias: Antigen NY-CO-13, bbl, BCC7, bfy, bhy, cellular tumor antigen p53, Cys 51 Stop, EGK_08142, FLJ92943, HGNC11998, I79_002739, LFS1, Li-Fraumeni syndrome, mutant p53, mutant tumor protein 53, OTTMUSP00000006194, p44, p53, p53 cellular tumor antigen, p53 protein, p53 tumor suppressor, p53 tumor suppressor phosphoprotein, phosphoprotein p53, Tp53, tp53.L, transformation related protein 53, transformation-related protein 53, Trp248, Trp53, tumor protein 53, tumor protein p53, tumor protein p53 (Li-Fraumeni syndrome), tumor protein p53 L homeolog, tumor suppressor p53, tumor suppressor p53 phosphoprotein, tumor suppressor protein p53, tumor supressor p53, Tumour Protein p53, XELAEV_180196761mg, Xp53, Xrel3
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 7157
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG
Antigen:
p53
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
P04637
Gene Symbols:
Tp53
Immunogen:
Recombinant full length protein within Human p53 aa 1-393/393.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin)
Clone:
PD01-32
Conjugate:
Unconjugated
Gene:
Tp53
Gene Alias:
Antigen NY-CO-13, bbl, BCC7, bfy, bhy, cellular tumor antigen p53, Cys 51 Stop, EGK_08142, FLJ92943, HGNC11998, I79_002739, LFS1, Li-Fraumeni syndrome, mutant p53, mutant tumor protein 53, OTTMUSP00000006194, p44, p53, p53 cellular tumor antigen, p53 protein, p53 tumor suppressor, p53 tumor suppressor phosphoprotein, phosphoprotein p53, Tp53, tp53.L, transformation related protein 53, transformation-related protein 53, Trp248, Trp53, tumor protein 53, tumor protein p53, tumor protein p53 (Li-Fraumeni syndrome), tumor protein p53 L homeolog, tumor suppressor p53, tumor suppressor p53 phosphoprotein, tumor suppressor protein p53, tumor supressor p53, Tumour Protein p53, XELAEV_180196761mg, Xp53, Xrel3
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
7157
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG
Antigen: CD127
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: P16871
Gene Symbols: Il7r
Immunogen: Recombinant protein within Human CD127 aa 340-439/459.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: JE37-10
Conjugate: Unconjugated
Gene: Il7r
Gene Alias: CD127, CD127 antigen, CDW127, IL 7 receptor, IL 7R a, IL 7R subunit alpha, IL 7R a, IL 7Ra, IL 7Ra, IL7 receptor, IL-7 receptor alpha chain, IL7 receptor subunit alpha, IL-7 receptor subunit alpha, IL7R, IL-7R, IL7R a, IL7R alpha, IL7R subunit alpha, IL-7R subunit alpha, IL7R a, IL7RA, IL-7RA, IL-7Ralpha, IL-7R-alpha, IL7Ra, ILRA, interleukin 7 receptor, interleukin 7 receptor alpha chain, interleukin 7 receptor isoform H5-6, Interleukin7 receptor subunit alpha, interleukin-7 receptor subunit alpha, MGC107557, sCD127, soluble IL 7 receptor, soluble IL 7R
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 3575
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG
Antigen:
CD127
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
P16871
Gene Symbols:
Il7r
Immunogen:
Recombinant protein within Human CD127 aa 340-439/459.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
JE37-10
Conjugate:
Unconjugated
Gene:
Il7r
Gene Alias:
CD127, CD127 antigen, CDW127, IL 7 receptor, IL 7R a, IL 7R subunit alpha, IL 7R a, IL 7Ra, IL 7Ra, IL7 receptor, IL-7 receptor alpha chain, IL7 receptor subunit alpha, IL-7 receptor subunit alpha, IL7R, IL-7R, IL7R a, IL7R alpha, IL7R subunit alpha, IL-7R subunit alpha, IL7R a, IL7RA, IL-7RA, IL-7Ralpha, IL-7R-alpha, IL7Ra, ILRA, interleukin 7 receptor, interleukin 7 receptor alpha chain, interleukin 7 receptor isoform H5-6, Interleukin7 receptor subunit alpha, interleukin-7 receptor subunit alpha, MGC107557, sCD127, soluble IL 7 receptor, soluble IL 7R
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
3575
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG