FEMA551049

IL-15 Monoclonal Antibody (C6), Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA551049-Each-of-1 In Stock ₹ 32,256.12

FEMA551049 - Each of 1

₹ 32,256.12

In Stock

Quantity

1

Base Price: ₹ 32,256.12

GST (18%): ₹ 5,806.102

Total Price: ₹ 38,062.222

Antigen

IL-15

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.

P40933, Q95253

Gene Symbols

IL15

Immunogen

Recombinant Human IL15 protein, Trp50-Ser162 (Accession #P40933)

Quantity

200 μL

Primary or Secondary

Primary

Target Species

Human, Porcine

Form

Liquid

Applications

Western Blot

Clone

C6

Conjugate

Unconjugated

Gene

IL15

Gene Alias

AI503618, il 15, Il15, IL-15, ILN, Interleukin, interleukin 15, Interleukin15, interleukin-15, MGC9721, M-IL-15

Host Species

Mouse

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

3600, 397683

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG κ

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Description

  • IL-15 (Interleukin 15 ) is a cytokine that regulates T and natural killer cell activation and proliferation
  • IL-15 and IL-2 share many biological activities as both have been found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity
  • The number of CD8+ memory cells is shown to be controlled by a balance between IL-15 and IL-2
  • IL-15 induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6
  • In mouse, studies suggest that IL-15 may increase the expression of apoptosis inhibitor Bcl-xL, possibly through the transcription activation activity of STAT6, and thus prevent apoptosis
  • IL-15 plays an important role in the growth and differentiation of T and B lymphocytes, natural killer cells, macrophages, and monocytes as well as activation of a number of important intracellular signaling molecules
  • As such, IL-15 could be essential for the immune responses, allograft rejection, and the pathogenesis of autoimmune diseases
  • Further, IL-15 is a widely expressed pro-inflammatory cytokine and has been shown to play a role in several inflammatory disorders, including rheumatoid arthritis, psoriasis and pulmonary inflammatory diseases
  • Emerging data suggest that IL-15 may serve as a good therapeutic target, as there appears to be a beneficial effect of IL-15 neutralization in models of psoriasis and diabetes.

Compare Similar Items

Show Difference

Img

Fischer Scientific

FEMA551049

--


Antigen:
IL-15

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.:
P40933, Q95253

Gene Symbols:
IL15

Immunogen:
Recombinant Human IL15 protein, Trp50-Ser162 (Accession #P40933)

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human, Porcine

Form:
Liquid

Applications:
Western Blot

Clone:
C6

Conjugate:
Unconjugated

Gene:
IL15

Gene Alias:
AI503618, il 15, Il15, IL-15, ILN, Interleukin, interleukin 15, Interleukin15, interleukin-15, MGC9721, M-IL-15

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
3600, 397683

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG κ

Img

Fischer Scientific

FEMA551050

--


Antigen:
IL-15

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.:
P40933, Q95253

Gene Symbols:
IL15

Immunogen:
Recombinant Human IL15 protein, Trp50-Ser162 (Accession #P40933)

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human, Porcine

Form:
Liquid

Applications:
Western Blot

Clone:
C6

Conjugate:
Unconjugated

Gene:
IL15

Gene Alias:
AI503618, il 15, Il15, IL-15, ILN, Interleukin, interleukin 15, Interleukin15, interleukin-15, MGC9721, M-IL-15

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
3600, 397683

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG κ

Img

Fischer Scientific

FEMA551053

--


Antigen:
PADI4

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.:
Q9UM07

Gene Symbols:
Padi4

Immunogen:
Recombinant Human PADI4 protein, Met1-Pro300 (Accession #Q9UM07)

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
C5

Conjugate:
Unconjugated

Gene:
Padi4

Gene Alias:
HL-60 PAD, PAD, PAD type IV, PAD4, Padi4, PADI5, PADI-H protein, PAD-R4, Pdi4, PDI5, peptidyl arginine deiminase 4, peptidyl arginine deiminase, type 4, peptidyl arginine deiminase, type IV, peptidyl arginine deiminase, type V, peptidylarginine deiminase IV, Peptidylarginine deiminase type alpha, protein-arginine deiminase type IV, Protein-arginine deiminase type-4

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
23569

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2b κ

Img

Fischer Scientific

FEMA551054

--


Antigen:
PADI4

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.:
Q9UM07

Gene Symbols:
Padi4

Immunogen:
Recombinant Human PADI4 protein, Met1-Pro300 (Accession #Q9UM07)

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
C5

Conjugate:
Unconjugated

Gene:
Padi4

Gene Alias:
HL-60 PAD, PAD, PAD type IV, PAD4, Padi4, PADI5, PADI-H protein, PAD-R4, Pdi4, PDI5, peptidyl arginine deiminase 4, peptidyl arginine deiminase, type 4, peptidyl arginine deiminase, type IV, peptidyl arginine deiminase, type V, peptidylarginine deiminase IV, Peptidylarginine deiminase type alpha, protein-arginine deiminase type IV, Protein-arginine deiminase type-4

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
23569

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2b κ