FEMA551050

IL-15 Monoclonal Antibody (C6), Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA551050-Each-of-1 In Stock ₹ 15,640.37

FEMA551050 - Each of 1

₹ 15,640.37

In Stock

Quantity

1

Base Price: ₹ 15,640.37

GST (18%): ₹ 2,815.267

Total Price: ₹ 18,455.637

Antigen

IL-15

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.

P40933, Q95253

Gene Symbols

IL15

Immunogen

Recombinant Human IL15 protein, Trp50-Ser162 (Accession #P40933)

Quantity

20 μL

Primary or Secondary

Primary

Target Species

Human, Porcine

Form

Liquid

Applications

Western Blot

Clone

C6

Conjugate

Unconjugated

Gene

IL15

Gene Alias

AI503618, il 15, Il15, IL-15, ILN, Interleukin, interleukin 15, Interleukin15, interleukin-15, MGC9721, M-IL-15

Host Species

Mouse

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

3600, 397683

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG κ

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Description

  • IL-15 (Interleukin 15 ) is a cytokine that regulates T and natural killer cell activation and proliferation
  • IL-15 and IL-2 share many biological activities as both have been found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity
  • The number of CD8+ memory cells is shown to be controlled by a balance between IL-15 and IL-2
  • IL-15 induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6
  • In mouse, studies suggest that IL-15 may increase the expression of apoptosis inhibitor Bcl-xL, possibly through the transcription activation activity of STAT6, and thus prevent apoptosis
  • IL-15 plays an important role in the growth and differentiation of T and B lymphocytes, natural killer cells, macrophages, and monocytes as well as activation of a number of important intracellular signaling molecules
  • As such, IL-15 could be essential for the immune responses, allograft rejection, and the pathogenesis of autoimmune diseases
  • Further, IL-15 is a widely expressed pro-inflammatory cytokine and has been shown to play a role in several inflammatory disorders, including rheumatoid arthritis, psoriasis and pulmonary inflammatory diseases
  • Emerging data suggest that IL-15 may serve as a good therapeutic target, as there appears to be a beneficial effect of IL-15 neutralization in models of psoriasis and diabetes.

Compare Similar Items

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Fischer Scientific

FEMA551050

--


Antigen:
IL-15

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.:
P40933, Q95253

Gene Symbols:
IL15

Immunogen:
Recombinant Human IL15 protein, Trp50-Ser162 (Accession #P40933)

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human, Porcine

Form:
Liquid

Applications:
Western Blot

Clone:
C6

Conjugate:
Unconjugated

Gene:
IL15

Gene Alias:
AI503618, il 15, Il15, IL-15, ILN, Interleukin, interleukin 15, Interleukin15, interleukin-15, MGC9721, M-IL-15

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
3600, 397683

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG κ

Img

Fischer Scientific

FEMA551053

--


Antigen:
PADI4

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.:
Q9UM07

Gene Symbols:
Padi4

Immunogen:
Recombinant Human PADI4 protein, Met1-Pro300 (Accession #Q9UM07)

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
C5

Conjugate:
Unconjugated

Gene:
Padi4

Gene Alias:
HL-60 PAD, PAD, PAD type IV, PAD4, Padi4, PADI5, PADI-H protein, PAD-R4, Pdi4, PDI5, peptidyl arginine deiminase 4, peptidyl arginine deiminase, type 4, peptidyl arginine deiminase, type IV, peptidyl arginine deiminase, type V, peptidylarginine deiminase IV, Peptidylarginine deiminase type alpha, protein-arginine deiminase type IV, Protein-arginine deiminase type-4

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
23569

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2b κ

Img

Fischer Scientific

FEMA551054

--


Antigen:
PADI4

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.:
Q9UM07

Gene Symbols:
Padi4

Immunogen:
Recombinant Human PADI4 protein, Met1-Pro300 (Accession #Q9UM07)

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
C5

Conjugate:
Unconjugated

Gene:
Padi4

Gene Alias:
HL-60 PAD, PAD, PAD type IV, PAD4, Padi4, PADI5, PADI-H protein, PAD-R4, Pdi4, PDI5, peptidyl arginine deiminase 4, peptidyl arginine deiminase, type 4, peptidyl arginine deiminase, type IV, peptidyl arginine deiminase, type V, peptidylarginine deiminase IV, Peptidylarginine deiminase type alpha, protein-arginine deiminase type IV, Protein-arginine deiminase type-4

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
23569

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2b κ

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FEMA551057

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Antigen:
Factor IX

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.:
P00740, P16292

Gene Symbols:
F9

Immunogen:
Recombinant Rabbit F9 protein, Met1-Arg146 (Accession #G1U9U2)

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human, Rabbit

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
C2

Conjugate:
Unconjugated

Gene:
F9

Gene Alias:
AW111646, Cf9, Cf-9, Christmas factor, coagulation factor 9, coagulation factor IX, coagulation factor IX (plasma thromboplastic component, Christmas disease, hemophilia B), Coagulation factor IXa heavy chain, Coagulation factor IXa light chain, EC 3.4.21.22, F9, F9 p22, factor 9, factor IX (Christmas factor) precursor, factor IX F9, Factor9, FIX, FIX F9, HEMB, P19, plasma thromboplastic component, plasma thromboplastin component, PTC, RP6-88D7.1, serine protease, THPH8

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
100009113, 2158

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1 κ