FEPA5144228

STAT3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEPA5144228-Each-of-1 In Stock ₹ 30,544.92

FEPA5144228 - Each of 1

₹ 30,544.92

In Stock

Quantity

1

Base Price: ₹ 30,544.92

GST (18%): ₹ 5,498.086

Total Price: ₹ 36,043.006

Antigen

STAT3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

STAT3

Gene Alias

1110034C02Rik, acute phase response factor, acute-phase response factor, ADMIO, ADMIO1, APRF, AW109958, DNA-binding protein APRF, FLJ20882, HIES, MGC16063, signal transducer and activator of transcription 3, signal transducer and activator of transcription 3 (acute-phase response factor), signal transducer, activator of transcription, acute-phase response factor, signal transduction and activation of transcription 3, STAT, STAT3, STAT-3, stat3 protein, STAT3b1, STAT3b2, transcription factor, Unknown (protein for MGC:128731), wu:fc15d02, wu:fl59g06, z-Stat3

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

6774

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG

Applications

ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation

Concentration

3 mg/mL

Formulation

PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4

Gene Accession No.

P40763

Gene Symbols

STAT3

Immunogen

Recombinant Human Signal transducer and activator of transcription 3 protein (50-240AA)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

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Description

  • STAT3 belongs to the family of STAT (signal transducers and activators of transcription) proteins which are phosphorylated by receptor associated kinases, translocate to the nucleus, and act as transcription factors in response to cytokines and growth factors
  • Coactivators such as CREB-binding protein are required for the transcriptional activation by STAT3
  • STAT3 can also be activated by Interferon-alpha, Interferon-gamma, EGF, PDGF and IL6
  • Phosphorylation on tyrosine 705 by JAK1 and JAK2 is essential for STAT3 dimer formation, nuclear translocation, and DNA binding activity
  • In humans, the STAT3 gene is located on the q arm of chromosome 17
  • STAT3 has been shown to be activated by IFN-alpha but not IFN-beta
  • The transcription factors associated with STAT3 are c-Jun and cyclic AMP-responsive enhancer binding protein (CREB)
  • STAT3 mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis
  • The small GTPase Rac1 has been shown to bind and regulate the activity of STAT3 while the PIAS3 protein is a specific inhibitor of STAT3
  • Three alternatively spliced transcript variants encoding distinct isoforms of STAT3 have been described
  • Deletion of the STAT3 gene in knock-out mice was lethal at the early embryonic stage.

Compare Similar Items

Show Difference

Img

Thermo Scientific

FEPA5144228

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Antigen:
STAT3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
STAT3

Gene Alias:
1110034C02Rik, acute phase response factor, acute-phase response factor, ADMIO, ADMIO1, APRF, AW109958, DNA-binding protein APRF, FLJ20882, HIES, MGC16063, signal transducer and activator of transcription 3, signal transducer and activator of transcription 3 (acute-phase response factor), signal transducer, activator of transcription, acute-phase response factor, signal transduction and activation of transcription 3, STAT, STAT3, STAT-3, stat3 protein, STAT3b1, STAT3b2, transcription factor, Unknown (protein for MGC:128731), wu:fc15d02, wu:fl59g06, z-Stat3

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
6774

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation

Concentration:
3 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4

Gene Accession No.:
P40763

Gene Symbols:
STAT3

Immunogen:
Recombinant Human Signal transducer and activator of transcription 3 protein (50-240AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Img

Thermo Scientific

FEPA5144232

--


Antigen:
FAM46C

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FAM46C

Gene Alias:
4930431B09Rik, AI449797, DN-384L23.3, Fam46c, family with sequence similarity 46 member C, family with sequence similarity 46, member C, Non-canonical poly(A) polymerase FAM46C, protein FAM46C, Protein FAM46C-like protein, putative nucleotidyltransferase FAM46C, TENT5C, Terminal nucleotidyltransferase 5C

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
54855, 74645

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
3 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4

Gene Accession No.:
Q5SSF7, Q5VWP2

Gene Symbols:
FAM46C

Immunogen:
Recombinant Human Terminal nucleotidyltransferase 5C protein (1-391AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Liquid

Img

Thermo Scientific

FEPA5144235

--


Antigen:
TALK-1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KCNK16

Gene Alias:
2P domain potassium channel Talk-1, 4731413G05Rik, K2p16.1, KCNK16, pancreatic potassium channel Talk-1, potassium channel subfamily K member 16, potassium channel, subfamily K, member 16, potassium channel, two pore domain subfamily K, member 16, potassium two pore domain channel subfamily K member 16, TALK1, TALK-1, TWIK-related alkaline pH-activated K(+) channel 1

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
83795

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

Applications:
ELISA, Immunohistochemistry (Paraffin)

Concentration:
3.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4

Gene Accession No.:
Q96T55

Gene Symbols:
KCNK16

Immunogen:
Recombinant Human Potassium channel subfamily K member 16 protein (259-309AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Img

Thermo Scientific

FEPA5144238

--


Antigen:
PRDX3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PRDX3

Gene Alias:
antioxidant protein, antioxidant protein 1, anti-oxidant protein 1, Aop1, AOP-1, AW822249, D0Tohi1, Ef2l, HBC189, Mer5, mitochondrial thioredoxin dependent peroxide reductase, mitochondrial Trx dependent peroxide reductase, perioredoxin-3, peroxiredoxin 3, peroxiredoxin III, Peroxiredoxin-3, Prdx3, PRO1748, Protein MER5, Protein MER5 homolog, Prx, Prx 3, PRx III, Prx3, PRX-3, Prx-III, SP22, SP-22, TDXM, thioredoxin-dependent peroxide reductase, mitochondrial

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
10935, 11757

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
3.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4

Gene Accession No.:
P20108, P30048

Gene Symbols:
PRDX3

Immunogen:
Recombinant Human Thioredoxin-dependent peroxide reductase, mitochondrial protein (63-256AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Liquid