FERMA548668

ATG5 Monoclonal Antibody (3C10B6), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FERMA548668-Each-of-1 In Stock ₹ 41,881.62

FERMA548668 - Each of 1

₹ 41,881.62

In Stock

Quantity

1

Base Price: ₹ 41,881.62

GST (18%): ₹ 7,538.692

Total Price: ₹ 49,420.312

Antigen

ATG5

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.05% sodium azide

Gene Accession No.

Q9H1Y0

Gene Symbols

Atg5

Immunogen

Purified recombinant fragment of human ATG5 (AA: 144-275) expressed in E. Coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Flow Cytometry, Immunohistochemistry, Western Blot

Clone

3C10B6

Conjugate

Unconjugated

Gene

Atg5

Gene Alias

2010107M05Rik; 3110067M24Rik; APG 5; APG5; APG5 autophagy 5 like (APG5L); APG5 autophagy 5-like protein; APG5 autophagy 5-like protein, isoform 1; APG5L; APG5-LIKE; apoptosis-specific protein; Apoptosis-specific protein (ASP); ASP; atg5; Atg-5; ATG5 autophagy related 5 homolog; ATG5 autophagy related 5 homolog (S. cerevisiae); atg5.L; Atg5l; Atg5-PA; autophagy 5-like protein; autophagy protein 5; autophagy related 5; autophagy related 5 L homeolog; autophagy related 5-like protein; Autophagy-related 5; autophagy-specific gene 5; AW319544; C88337; CG1643; CG1643-PA; DmAtg5; Dmel\CG1643; Dmel_CG1643; hAPG5; hypothetical protein LOC532686; LD34980p; Paddy; XELAEV_18027227mg; zgc:100934

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

9474

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG2b

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Description

  • ATG5 (Autophagy Related 5) is an important element for autophagy and may play an important role in the apoptotic process
  • ATG5 is also involved in other cellular processes that include mitochondrial quality control after oxidative damage, negative regulation of the innate anti-viral immune response, lymphocyte development and proliferation, MHC II antigen presentation, and adipocyte differentiation
  • Following conjugation to ATG12, the conjugate participates in the formation of autophagosome
  • ATG5 contributes to autophagic cell death by interacting with Fas-associated protein with death domain (FADD)
  • The ATG5-ATG12 conjugate forms a cup-shaped isolation membrane that then detaches from the membrane immediately before or after autophagosome formation is completed
  • APG5 may play a role in the apoptotic process, possibly within the modified cytoskeleton
  • Further, APG5 expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity
  • The APG5-APG12 conjugate also associates with innate immune response proteins such as RIG-I and VISA (also known as IPS-1), inhibiting type I interferon production and permitting viral replication in host cells
  • Diseases associated with ATG5 dysfunction include spinocerebellar ataxia.

Compare Similar Items

Show Difference

Img

Thermo Scientific

FERMA548668

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Antigen:
ATG5

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
Q9H1Y0

Gene Symbols:
Atg5

Immunogen:
Purified recombinant fragment of human ATG5 (AA: 144-275) expressed in E. Coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunohistochemistry, Western Blot

Clone:
3C10B6

Conjugate:
Unconjugated

Gene:
Atg5

Gene Alias:
2010107M05Rik; 3110067M24Rik; APG 5; APG5; APG5 autophagy 5 like (APG5L); APG5 autophagy 5-like protein; APG5 autophagy 5-like protein, isoform 1; APG5L; APG5-LIKE; apoptosis-specific protein; Apoptosis-specific protein (ASP); ASP; atg5; Atg-5; ATG5 autophagy related 5 homolog; ATG5 autophagy related 5 homolog (S. cerevisiae); atg5.L; Atg5l; Atg5-PA; autophagy 5-like protein; autophagy protein 5; autophagy related 5; autophagy related 5 L homeolog; autophagy related 5-like protein; Autophagy-related 5; autophagy-specific gene 5; AW319544; C88337; CG1643; CG1643-PA; DmAtg5; Dmel\CG1643; Dmel_CG1643; hAPG5; hypothetical protein LOC532686; LD34980p; Paddy; XELAEV_18027227mg; zgc:100934

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
9474

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2b

Img

Thermo Scientific

FERMA548670

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Antigen:
NAPSA

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
O96009

Gene Symbols:
NAPSA

Immunogen:
Synthesized peptide of human NAPSA (AA: KPIFVPLSNYRDVQYc).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Clone:
5A6E4

Conjugate:
Unconjugated

Gene:
NAPSA

Gene Alias:
asp 4; ASP4; Aspartyl protease 4; KAP; Kdap; KDAP-1; kidney-derived aspartic protease-like protein; Nap; NAP1; NAPA; Napsa; napsin A aspartic peptidase; napsin-1; Napsin-A; pronapsin; pronapsin A; SNAPA; TA01/TA02

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
9476

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1

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Thermo Scientific

FERMA548673

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Antigen:
Rubicon

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
Q92622

Gene Symbols:
RUBCN

Immunogen:
Purified recombinant fragment of human RUBCN (AA: 859-972) expressed in E. Coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Western Blot

Clone:
4F5B5

Conjugate:
Unconjugated

Gene:
RUBCN

Gene Alias:
1700021K19Rik; 5330403K09; baron; Beclin-1 associated RUN domain containing protein; KIAA0226; mKIAA0226; RGD1305422; RIKEN cDNA 1700021K19 gene; RUBCN; Rubicon; RUN and cysteine rich domain containing beclin 1 interacting protein; RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein; run domain Beclin-1 interacting and cysteine-rich containing protein; run domain Beclin-1 interacting and cystein-rich containing protein; run domain Beclin-1-interacting and cysteine-rich domain-containing protein; RUN domain protein as Beclin 1-interacting and cysteine-rich containing; rundataxin; SCAR15; similar to mKIAA0226 protein

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
9711

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1

Img

Thermo Scientific

FERMA548677

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Antigen:
HDAC6

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
Q9UBN7

Gene Symbols:
HDAC6

Immunogen:
Purified recombinant fragment of human HDAC6 (AA: 482-800) expressed in E. Coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunohistochemistry, Western Blot

Clone:
4G6F9

Conjugate:
Unconjugated

Gene:
HDAC6

Gene Alias:
CPBHM; FLJ16239; Hd6; HDA6; Hdac5; Hdac6; histone deacetylase 5; histone deacetylase 6; Histone deacetylase mHDA2; JM21; KIAA0901; mHDA2; PPP1R90; protein phosphatase 1, regulatory subunit 90; scurfy candidate 6; Sfc6

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
10013

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2b