PA146178
ATG5 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA146178-Each-of-1 | In Stock | ₹ 50,095.38 |
PA146178 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,095.38
GST (18%): ₹ 9,017.168
Total Price: ₹ 59,112.548
Antigen
ATG5
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Atg5
Gene Alias
2010107M05Rik; 3110067M24Rik; APG 5; APG5; APG5 autophagy 5 like (APG5L); APG5 autophagy 5-like protein; APG5 autophagy 5-like protein, isoform 1; APG5L; APG5-LIKE; apoptosis-specific protein; Apoptosis-specific protein (ASP); ASP; atg5; Atg-5; ATG5 autophagy related 5 homolog; ATG5 autophagy related 5 homolog (S. cerevisiae); atg5.L; Atg5l; Atg5-PA; autophagy 5-like protein; autophagy protein 5; autophagy related 5; autophagy related 5 L homeolog; autophagy related 5-like protein; Autophagy-related 5; autophagy-specific gene 5; AW319544; C88337; CG1643; CG1643-PA; DmAtg5; Dmel\CG1643; Dmel_CG1643; hAPG5; hypothetical protein LOC532686; LD34980p; Paddy; XELAEV_18027227mg; zgc:100934
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
100735170, 100739102, 11793, 31666, 365601, 443756, 494180, 532686, 641362, 9474
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunomicroscopy, Immunoprecipitation, Proximity Ligation Assay, Radioimmune Assays (RIA), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
Q3MQ04, Q3MQ06, Q3MQ24, Q99J83, Q9H1Y0, Q9W3R7
Gene Symbols
Atg5, atg5.L
Immunogen
Synthetic peptide made to an N-terminal region of the human ATG5 protein.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Bovine, Drosophila, Fish, Guinea Pig, Human, Mouse, Non-human Primate, Porcine, Rat, Reptile, X. laevis, Zebrafish
Product Type
Antibody
Isotype
IgG
Related Products
Description
- In Western Blot, a band is seen ∽56 kDa representing the ATG5-ATG12 complex, the molecular weight of human ATG5 is ∽33 kDa
- Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended
- Suggested positive control: antigen standard for ATG5 (transient overexpression lysate), mouse wildtype ES cell lysate
- ATG5 (Autophagy Related 5) is an important element for autophagy and may play an important role in the apoptotic process
- ATG5 is also involved in other cellular processes that include mitochondrial quality control after oxidative damage, negative regulation of the innate anti-viral immune response, lymphocyte development and proliferation, MHC II antigen presentation, and adipocyte differentiation
- Following conjugation to ATG12, the conjugate participates in the formation of autophagosome
- ATG5 contributes to autophagic cell death by interacting with Fas-associated protein with death domain (FADD)
- The ATG5-ATG12 conjugate forms a cup-shaped isolation membrane that then detaches from the membrane immediately before or after autophagosome formation is completed
- APG5 may play a role in the apoptotic process, possibly within the modified cytoskeleton
- Further, APG5 expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity
- The APG5-APG12 conjugate also associates with innate immune response proteins such as RIG-I and VISA (also known as IPS-1), inhibiting type I interferon production and permitting viral replication in host cells
- Diseases associated with ATG5 dysfunction include spinocerebellar ataxia.
Compare Similar Items
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Antigen: ATG5
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Atg5
Gene Alias: 2010107M05Rik; 3110067M24Rik; APG 5; APG5; APG5 autophagy 5 like (APG5L); APG5 autophagy 5-like protein; APG5 autophagy 5-like protein, isoform 1; APG5L; APG5-LIKE; apoptosis-specific protein; Apoptosis-specific protein (ASP); ASP; atg5; Atg-5; ATG5 autophagy related 5 homolog; ATG5 autophagy related 5 homolog (S. cerevisiae); atg5.L; Atg5l; Atg5-PA; autophagy 5-like protein; autophagy protein 5; autophagy related 5; autophagy related 5 L homeolog; autophagy related 5-like protein; Autophagy-related 5; autophagy-specific gene 5; AW319544; C88337; CG1643; CG1643-PA; DmAtg5; Dmel\CG1643; Dmel_CG1643; hAPG5; hypothetical protein LOC532686; LD34980p; Paddy; XELAEV_18027227mg; zgc:100934
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 100735170, 100739102, 11793, 31666, 365601, 443756, 494180, 532686, 641362, 9474
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunomicroscopy, Immunoprecipitation, Proximity Ligation Assay, Radioimmune Assays (RIA), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: Q3MQ04, Q3MQ06, Q3MQ24, Q99J83, Q9H1Y0, Q9W3R7
Gene Symbols: Atg5, atg5.L
Immunogen: Synthetic peptide made to an N-terminal region of the human ATG5 protein.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Bovine, Drosophila, Fish, Guinea Pig, Human, Mouse, Non-human Primate, Porcine, Rat, Reptile, X. laevis, Zebrafish
Product Type: Antibody
Isotype: IgG
Antigen:
ATG5
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Atg5
Gene Alias:
2010107M05Rik; 3110067M24Rik; APG 5; APG5; APG5 autophagy 5 like (APG5L); APG5 autophagy 5-like protein; APG5 autophagy 5-like protein, isoform 1; APG5L; APG5-LIKE; apoptosis-specific protein; Apoptosis-specific protein (ASP); ASP; atg5; Atg-5; ATG5 autophagy related 5 homolog; ATG5 autophagy related 5 homolog (S. cerevisiae); atg5.L; Atg5l; Atg5-PA; autophagy 5-like protein; autophagy protein 5; autophagy related 5; autophagy related 5 L homeolog; autophagy related 5-like protein; Autophagy-related 5; autophagy-specific gene 5; AW319544; C88337; CG1643; CG1643-PA; DmAtg5; Dmel\CG1643; Dmel_CG1643; hAPG5; hypothetical protein LOC532686; LD34980p; Paddy; XELAEV_18027227mg; zgc:100934
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
100735170, 100739102, 11793, 31666, 365601, 443756, 494180, 532686, 641362, 9474
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunomicroscopy, Immunoprecipitation, Proximity Ligation Assay, Radioimmune Assays (RIA), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
Q3MQ04, Q3MQ06, Q3MQ24, Q99J83, Q9H1Y0, Q9W3R7
Gene Symbols:
Atg5, atg5.L
Immunogen:
Synthetic peptide made to an N-terminal region of the human ATG5 protein.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Bovine, Drosophila, Fish, Guinea Pig, Human, Mouse, Non-human Primate, Porcine, Rat, Reptile, X. laevis, Zebrafish
Product Type:
Antibody
Isotype:
IgG
Antigen: TOM70
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TOMM70
Gene Alias: 2610044B22Rik; D16Ium22; D16Ium22e; D16Wsu109e; FLJ90470; KIAA0719; Mitochondrial import receptor subunit TOM70; mitochondrial precursor proteins import receptor; mKIAA0719; Tom70; Tomm70; Tomm70a; Translocase of outer membrane 70 kDa subunit; translocase of outer mitochondrial membrane 70; translocase of outer mitochondrial membrane 70 homolog A; translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae); translocase of outer mitochondrial membrane 70 homolog A (yeast); translocase of outer mitochondrial membrane protein 70
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 100352274, 28185, 304017, 9868
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: O94826, Q75Q39, Q9CZW5
Gene Symbols: TOMM70, Tomm70a
Immunogen: Synthetic peptide made to a region within residues 1-100 of the human protein. [Swiss-Prot# O94826].
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rabbit, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
TOM70
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TOMM70
Gene Alias:
2610044B22Rik; D16Ium22; D16Ium22e; D16Wsu109e; FLJ90470; KIAA0719; Mitochondrial import receptor subunit TOM70; mitochondrial precursor proteins import receptor; mKIAA0719; Tom70; Tomm70; Tomm70a; Translocase of outer membrane 70 kDa subunit; translocase of outer mitochondrial membrane 70; translocase of outer mitochondrial membrane 70 homolog A; translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae); translocase of outer mitochondrial membrane 70 homolog A (yeast); translocase of outer mitochondrial membrane protein 70
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
100352274, 28185, 304017, 9868
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
O94826, Q75Q39, Q9CZW5
Gene Symbols:
TOMM70, Tomm70a
Immunogen:
Synthetic peptide made to a region within residues 1-100 of the human protein. [Swiss-Prot# O94826].
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rabbit, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-CREB (Ser133)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CREB1
Gene Alias: 2310001E10Rik; 3526402H21Rik; active transcription factor CREB; AV083133; cAMP response element binding protein 1; cAMP responsive element binding protein 1; cAMP-response element-binding protein-1; cAMP-responsive element-binding protein 1; CREB; CREB1; Creb-1; cyclic adenosine 3',5'-monophosphate response element-binding protein CREB; cyclic AMP-responsive element-binding protein 1; htCREB; MGC9284; OTTHUMP00000206661; OTTHUMP00000206662; OTTHUMP00000206667; transactivator protein; Y protein
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12912, 81646
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry, Western Blot
Concentration: __
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.: P15337, Q01147
Gene Symbols: CREB1
Immunogen: Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser133 of rat CREB1 conjugated to KLH
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-CREB (Ser133)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CREB1
Gene Alias:
2310001E10Rik; 3526402H21Rik; active transcription factor CREB; AV083133; cAMP response element binding protein 1; cAMP responsive element binding protein 1; cAMP-response element-binding protein-1; cAMP-responsive element-binding protein 1; CREB; CREB1; Creb-1; cyclic adenosine 3',5'-monophosphate response element-binding protein CREB; cyclic AMP-responsive element-binding protein 1; htCREB; MGC9284; OTTHUMP00000206661; OTTHUMP00000206662; OTTHUMP00000206667; transactivator protein; Y protein
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12912, 81646
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Concentration:
__
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.:
P15337, Q01147
Gene Symbols:
CREB1
Immunogen:
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser133 of rat CREB1 conjugated to KLH
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: LRRK2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: LRRK2
Gene Alias: 4921513O20Rik; 9330188B09Rik; augmented in rheumatoid arthritis 17; AURA17; AW561911; BC 300-268; cI-46; D630001M17Rik; DARDARIN; DKFZp434H2111; FLJ45829; Gm927; leucine rich repeat kinase 2; leucine-rich repeat kinase 2; leucine-rich repeat serine/threonine-protein kinase 2; LRR kinase 2; LRRK 2; Lrrk2; LRRK-2; PARK8; RIPK7; ROCO2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 120892, 300160, 66725
Content And Storage: 4° C, do not freeze
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 1 mg/mL
Formulation: phosphate, tris citrate with 0.05% sodium azide; pH 7-8
Gene Accession No.: Q5S006, Q5S007
Gene Symbols: LRRK2
Immunogen: A synthetic peptide made to a C-terminal region, within residues 2500-2527 of the human LRRK2 protein, conjugated to KLH
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
LRRK2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
LRRK2
Gene Alias:
4921513O20Rik; 9330188B09Rik; augmented in rheumatoid arthritis 17; AURA17; AW561911; BC 300-268; cI-46; D630001M17Rik; DARDARIN; DKFZp434H2111; FLJ45829; Gm927; leucine rich repeat kinase 2; leucine-rich repeat kinase 2; leucine-rich repeat serine/threonine-protein kinase 2; LRR kinase 2; LRRK 2; Lrrk2; LRRK-2; PARK8; RIPK7; ROCO2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
120892, 300160, 66725
Content And Storage:
4° C, do not freeze
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
1 mg/mL
Formulation:
phosphate, tris citrate with 0.05% sodium azide; pH 7-8
Gene Accession No.:
Q5S006, Q5S007
Gene Symbols:
LRRK2
Immunogen:
A synthetic peptide made to a C-terminal region, within residues 2500-2527 of the human LRRK2 protein, conjugated to KLH
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG