PA14619

Phospho-CREB (Ser133) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PA14619-Each-of-1 In Stock ₹ 47,528.58

PA14619 - Each of 1

₹ 47,528.58

In Stock

Quantity

1

Base Price: ₹ 47,528.58

GST (18%): ₹ 8,555.144

Total Price: ₹ 56,083.724

Antigen

Phospho-CREB (Ser133)

Classification

Polyclonal

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.

P15337, Q01147

Gene Symbols

CREB1

Immunogen

Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser133 of rat CREB1 conjugated to KLH

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry, Western Blot

Conjugate

Unconjugated

Gene

CREB1

Gene Alias

2310001E10Rik; 3526402H21Rik; active transcription factor CREB; AV083133; cAMP response element binding protein 1; cAMP responsive element binding protein 1; cAMP-response element-binding protein-1; cAMP-responsive element-binding protein 1; CREB; CREB1; Creb-1; cyclic adenosine 3',5'-monophosphate response element-binding protein CREB; cyclic AMP-responsive element-binding protein 1; htCREB; MGC9284; OTTHUMP00000206661; OTTHUMP00000206662; OTTHUMP00000206667; transactivator protein; Y protein

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12912, 81646

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • This antibody is predicted to react with bovine, canine, chicken, human, mouse, non-human primate, rat, sheep, Xenopus and zebrafish based on 100% sequence homology
  • This antibody is specific for the ∽45 kDa CREB phosphorylated at Ser133 in Western blots of rat brain lysates
  • Immunolabeling can be blocked by lambda-phosphatase treatment
  • CREB (Cyclic AMP response element binding protein) is a 43 kDa basic/leucine zipper transcription factor that binds the cyclic AMP response element (CRE) and activates transcription in response to a variety of extracellular signals including neurotransmitters, hormones, membrane depolarization, and growth and neurotrophic factors
  • Activation of CREB is dependent upon the phosphorylation of serine 133
  • Phosphorylation of CREB occurs via p44/42 MAP kinase and p90RSK, and via p38 MAP kinase and MSK1
  • Although CREB will bind DNA independent of its phosphorylation state, only the phosphorylated form is competent as a transcription factor
  • CREB binding protein (CBP), a transcriptional coactivator that directly interacts with CREB, binds to CREB in the region of serine 133
  • CREB is involved in different cellular processes including the synchronization of circadian rhythmicity, differentiation of adipose cells, and learning and memory
  • In humans, the gene is located on the q arm of chromosome 2
  • Diseases associated with CREB dysfunction include Alzheimer’s Disease, histiocytoma and soft tissue melanoma.

Compare Similar Items

Show Difference

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Thermo Scientific

PA14619

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Antigen:
Phospho-CREB (Ser133)

Classification:
Polyclonal

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P15337, Q01147

Gene Symbols:
CREB1

Immunogen:
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser133 of rat CREB1 conjugated to KLH

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry, Western Blot

Conjugate:
Unconjugated

Gene:
CREB1

Gene Alias:
2310001E10Rik; 3526402H21Rik; active transcription factor CREB; AV083133; cAMP response element binding protein 1; cAMP responsive element binding protein 1; cAMP-response element-binding protein-1; cAMP-responsive element-binding protein 1; CREB; CREB1; Creb-1; cyclic adenosine 3',5'-monophosphate response element-binding protein CREB; cyclic AMP-responsive element-binding protein 1; htCREB; MGC9284; OTTHUMP00000206661; OTTHUMP00000206662; OTTHUMP00000206667; transactivator protein; Y protein

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12912, 81646

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PA146194

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Antigen:
LRRK2

Classification:
Polyclonal

Formulation:
phosphate, tris citrate with 0.05% sodium azide; pH 7-8

Gene Accession No.:
Q5S006, Q5S007

Gene Symbols:
LRRK2

Immunogen:
A synthetic peptide made to a C-terminal region, within residues 2500-2527 of the human LRRK2 protein, conjugated to KLH

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
LRRK2

Gene Alias:
4921513O20Rik; 9330188B09Rik; augmented in rheumatoid arthritis 17; AURA17; AW561911; BC 300-268; cI-46; D630001M17Rik; DARDARIN; DKFZp434H2111; FLJ45829; Gm927; leucine rich repeat kinase 2; leucine-rich repeat kinase 2; leucine-rich repeat serine/threonine-protein kinase 2; LRR kinase 2; LRRK 2; Lrrk2; LRRK-2; PARK8; RIPK7; ROCO2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
120892, 300160, 66725

Content And Storage:
4° C, do not freeze

Form:
Liquid

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PA14620

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Antigen:
Phospho-Dynamin 1 (Ser774)

Classification:
Polyclonal

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P21575, P39053

Gene Symbols:
DNM1

Immunogen:
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser774 of rat DNM1 conjugated to KLH

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Conjugate:
Unconjugated

Gene:
DNM1

Gene Alias:
AI838169; B-dynamin; D100; Dnm; Dnm1; Dyn1; dynamin 1; Dynamin BREDNM19; dynamin i; dynamin, brain; Dynamin1; Dynamin-1; EC 3.6.5.5; EIEE31; Ftfl; Kiaa4093; mKIAA4093; Neuronal dynamin; OTTHUMP00000215500

Host Species:
Sheep

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13429, 140694

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

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Thermo Scientific

PA146203

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Antigen:
NSE

Classification:
Polyclonal

Formulation:
whole serum with 5mM sodium azide

Gene Accession No.:
P07323, P09104, P17183

Gene Symbols:
ENO2

Immunogen:
Recombinant full length human NSE purified from E. coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Conjugate:
Unconjugated

Gene:
ENO2

Gene Alias:
2-phospho-D-glycerate hydrolyase; 2-phospho-D-glycerate hydro-lyase; AI837106; D6Ertd375e; Eno; ENO2; Eno-2; ENOG; Enolase 2; enolase 2 (gamma, neuronal); enolase 2, gamma neuronal; enolase 2, gamma, neuronal; epididymis secretory protein Li 279; gamma enolase; gamma-enolase; gamma-enolase-like; gamma-subunit of enolase; HEL-S-279; LOC100911625; Neural enolase; neuron specific enolase; neuron specific gamma enolase; Neuronal Enolase; neuronal enriched enolase; neurone-specific enolase; neuron-specific enolase; NSE; RNEN3

Host Species:
Rabbit

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
13807, 2026, 24334

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid