PA14625

Phospho-ELK1 (Ser383) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA14625-Each-of-1 In Stock ₹ 47,015.22

PA14625 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

Phospho-ELK1 (Ser383)

Classification

Polyclonal

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.

A4GTP4, P19419, P41969

Gene Symbols

ELK1

Immunogen

Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser383 of human ELK1 conjugated to KLH

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Conjugate

Unconjugated

Gene

ELK1

Gene Alias

ELK 1; ELK1; Elk-1; ELK1, ETS transcription factor; ELK1, member of ETS oncogene family; ETS domain-containing protein Elk-1; ETS transcription factor ELK1; ETS-like gene 1; Oncogene Elk1; tyrosine kinase (ELK1) oncogene

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

13712, 2002, 314436

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • This antibody is predicted to react with canine, mouse, non-human primate and zebrafish based on 100% sequence homology
  • This antibody is specific for ∽46 kDa Elk-1 phosphorylated at Ser383 in Western blots using phospho and dephospho Elk-1 recombinant protein
  • Immunolabeling is blocked by the phosphopeptide used as the antigen but not by the corresponding dephosphopeptide
  • ELK1 is a component of the ternary complex that binds the serum response element (SRE) and mediates gene activity in response to serum and growth factors
  • ELK1 is phosphorylated by MAP kinase pathways at a cluster of S/T motifs at its C-terminus
  • Phosphorylation at these sites, particularly Ser383, is critical for transcriptional activation by ELK1
  • ELK1 appears to be a direct target of activated MAP kinase
  • Biochemical studies indicate that ELK1 is a good substrate for MAP kinase, the kinetics of ELK1 phosphorylation and activation correlate with MAP kinase activity, and interfering mutants of MAP kinase block ELK1 activation in vivo
  • ELK1 is a nuclear target for the ras-raf-MAPK signaling cascade
  • Alternatively spliced transcript variants encoding the same protein have been found for ELK1.

Compare Similar Items

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Thermo Scientific

PA14625

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Antigen:
Phospho-ELK1 (Ser383)

Classification:
Polyclonal

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
A4GTP4, P19419, P41969

Gene Symbols:
ELK1

Immunogen:
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser383 of human ELK1 conjugated to KLH

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
ELK1

Gene Alias:
ELK 1; ELK1; Elk-1; ELK1, ETS transcription factor; ELK1, member of ETS oncogene family; ETS domain-containing protein Elk-1; ETS transcription factor ELK1; ETS-like gene 1; Oncogene Elk1; tyrosine kinase (ELK1) oncogene

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13712, 2002, 314436

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PA146253

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Antigen:
mGluR6

Classification:
Polyclonal

Formulation:
tris glycine with 0.02% sodium azide

Gene Accession No.:
P35349, Q5NCH9

Gene Symbols:
GRM6

Immunogen:
C-terminus of rat mGluR6.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot

Conjugate:
Unconjugated

Gene:
GRM6

Gene Alias:
BC021919; CSNB1B; G protein-coupled receptor GRM6; G protein-coupled receptor, family C, group 1, member F; glutamate metabotropic receptor 6; glutamate receptor; glutamate receptor, metabotropic 6; Gm3; GPRC1F; Grm6; Metabotropic glutamate receptor 6; mGlu6; MGLUR6; nerg1; nob2; nob3; nob4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
108072, 24419

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PA146256

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Antigen:
Humanin

Classification:
Polyclonal

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q8IVG9

Gene Symbols:
MT-RNR2

Immunogen:
Residues 9-24 of the human Humanin protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
MT-RNR2

Gene Alias:
BCL2L4; HN1; Humanin-like 1; humanin-like protein 1; mitochondrially encoded 16S RNA; MTRNR2; MT-RNR2; MTRNR2L1; MT-RNR2-like 1; MTRNR2-like 1; MT-RNR2-like protein 1; RNR2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4550

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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Thermo Scientific

PA146286

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Antigen:
LC3B

Classification:
Polyclonal

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
A6NCE7, O41515, Q62625, Q9CQV6, Q9GZQ8

Gene Symbols:
MAP1LC3B, MAP1LC3B2

Immunogen:
N-terminal region of the human LC3, isoform B protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Bacteria, Bovine, Canine, Human, Mouse, Non-human Primate, Porcine, Rat, Zebrafish

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunomicroscopy, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
MAP1LC3B2

Gene Alias:
1010001C15Rik; Atg8; ATG8E; ATG8F; ATG8G; Autophagy-related protein LC3 B; autophagy-related ubiquitin-like modifier LC3 B; LC3; LC3 beta; LC3A; LC3B; light chain 3; MAP1 light chain 3-like protein 2; MAP1A/1B light chain 3 B; MAP1A/1BLC3; MAP1A/MAP1B LC3 A; MAP1A/MAP1B LC3 B; MAP1A/MAP1B light chain 3 B; Map1alc3; MAP1BLC3; MAP1LC3; MAP1LC3A; MAP1LC3B; MAP1LC3B2; MAP1LC3B-a; microtubule associated protein 1 light chain 3 beta; microtubule associated protein 1 light chain 3 beta 2; microtubule-associated protein 1 light chain 3; microtubule-associated protein 1 light chain 3 beta; microtubule-associated protein 1 light chain 3 beta 2; microtubule-associated proteins 1A/1B light chain 3; microtubule-associated proteins 1A/1B light chain 3 beta 2; Microtubule-associated proteins 1A/1B light chain 3B; Microtubule-associated proteins 1A/1B light chain 3B-like; Microtubule-associated proteins 1A/1B light chain 3B-like protein; Mpl3; RP11-346K17.1; wu:fb60g11; zbs559; zgc:56434

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100359928, 100462754, 322425, 408001, 479619, 643246, 64862, 67443, 81631

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid