PA14620

Phospho-Dynamin 1 (Ser774) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA14620-Each-of-1 In Stock ₹ 47,271.90

PA14620 - Each of 1

₹ 47,271.90

In Stock

Quantity

1

Base Price: ₹ 47,271.90

GST (18%): ₹ 8,508.942

Total Price: ₹ 55,780.842

Antigen

Phospho-Dynamin 1 (Ser774)

Classification

Polyclonal

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.

P21575, P39053

Gene Symbols

DNM1

Immunogen

Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser774 of rat DNM1 conjugated to KLH

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Immunohistochemistry, Western Blot

Conjugate

Unconjugated

Gene

DNM1

Gene Alias

AI838169; B-dynamin; D100; Dnm; Dnm1; Dyn1; dynamin 1; Dynamin BREDNM19; dynamin i; dynamin, brain; Dynamin1; Dynamin-1; EC 3.6.5.5; EIEE31; Ftfl; Kiaa4093; mKIAA4093; Neuronal dynamin; OTTHUMP00000215500

Host Species

Sheep

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

13429, 140694

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • This antibody is predicted to react with bovine, canine, chicken, human, mouse and non-human primate based on 100% sequence homology
  • It does not cross-react with other purified substrates of cdk5 (amphiphysin and synapsin)
  • This antibody is specific for the ∽95 kDa Dynamin protein phosphorylated at Ser774in Western blots of rat brain lysates
  • This antibody labels the purified protein phosphorylated in vitro by cdk5 but not by PKC
  • Immunolabeling is blocked by the phosphopeptide used as the antigen but not by the corresponding dephosphopeptide
  • Store at -20oC short term, 80oC long term
  • Dynamin is a GTPase required for endocytosis of clathrin coated vesicles from the membrane
  • Dynamin's involvement in endocytosis was first discovered during the characterization of the temperature sensitive parylytic shibire mutation from Drosophila melanogaster
  • Three closely related isoforms have been identified in mammals
  • Dynamin1 is expressed exclusively in neurons, dynamin2 is ubiquitously expressed and dynamin3 is expressed primarily in the testes
  • Each of these isoforms of dynamin also has several splice variants
  • This suggests that each isoform/splice variant may have separate intracellular targets or function in the budding of distinct vesicle types
  • Common domain features of the dynamin proteins include an amino acid terminal GTPase domain, a central pleckstrin homology domain and a highly basic proline rich carboxyl terminus with several Src homology 3 (SH3) domains
  • These SH3 domains target the dynamin to the clathrin coated pit
  • Dynamin is known to interact with at least two proteins, AP2 adaptor protein complex and amphiphysin.

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Show Difference

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Thermo Scientific

PA14620

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Antigen:
Phospho-Dynamin 1 (Ser774)

Classification:
Polyclonal

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P21575, P39053

Gene Symbols:
DNM1

Immunogen:
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser774 of rat DNM1 conjugated to KLH

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Conjugate:
Unconjugated

Gene:
DNM1

Gene Alias:
AI838169; B-dynamin; D100; Dnm; Dnm1; Dyn1; dynamin 1; Dynamin BREDNM19; dynamin i; dynamin, brain; Dynamin1; Dynamin-1; EC 3.6.5.5; EIEE31; Ftfl; Kiaa4093; mKIAA4093; Neuronal dynamin; OTTHUMP00000215500

Host Species:
Sheep

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13429, 140694

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

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PA146203

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Antigen:
NSE

Classification:
Polyclonal

Formulation:
whole serum with 5mM sodium azide

Gene Accession No.:
P07323, P09104, P17183

Gene Symbols:
ENO2

Immunogen:
Recombinant full length human NSE purified from E. coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Conjugate:
Unconjugated

Gene:
ENO2

Gene Alias:
2-phospho-D-glycerate hydrolyase; 2-phospho-D-glycerate hydro-lyase; AI837106; D6Ertd375e; Eno; ENO2; Eno-2; ENOG; Enolase 2; enolase 2 (gamma, neuronal); enolase 2, gamma neuronal; enolase 2, gamma, neuronal; epididymis secretory protein Li 279; gamma enolase; gamma-enolase; gamma-enolase-like; gamma-subunit of enolase; HEL-S-279; LOC100911625; Neural enolase; neuron specific enolase; neuron specific gamma enolase; Neuronal Enolase; neuronal enriched enolase; neurone-specific enolase; neuron-specific enolase; NSE; RNEN3

Host Species:
Rabbit

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
13807, 2026, 24334

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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PA146215

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Antigen:
OXPAT

Classification:
Polyclonal

Formulation:
PBS with 30% glycerol and 0.1% sodium azide

Gene Accession No.:
A6QLL0, Q00G26, Q8BVZ1

Gene Symbols:
Plin5

Immunogen:
Synthetic peptide made to a region of the Human OXPAT protein, within residues 300-400.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Human, Mouse, Porcine

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Gene:
Plin5

Gene Alias:
2310076L09Rik; AI415325; AW109675; lipid droplet associated protein; lipid droplet-associated protein PAT-1; Lipid storage droplet protein 5; LSDA5; LSDP5; Mldp; Myocardial LD protein; Oxpat; Pat1; PAT-1; perilipin 5; perilipin-5; Plin5

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100142670, 440503, 531199, 66968

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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PA146216

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Antigen:
OXPAT

Classification:
Polyclonal

Formulation:
PBS with 30% glycerol and 0.1% sodium azide

Gene Accession No.:
Q00G26, Q8BVZ1

Gene Symbols:
Plin5

Immunogen:
C-terminal region of the mouse OXPAT protein, with in residues 400-463 [Uniprot# Q8BVZ1].

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
Plin5

Gene Alias:
2310076L09Rik; AI415325; AW109675; lipid droplet associated protein; lipid droplet-associated protein PAT-1; Lipid storage droplet protein 5; LSDA5; LSDP5; Mldp; Myocardial LD protein; Oxpat; Pat1; PAT-1; perilipin 5; perilipin-5; Plin5

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
440503, 66968

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid