PA14679

Tyrosine Hydroxylase Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA14679-Each-of-1 In Stock ₹ 50,737.08

PA14679 - Each of 1

₹ 50,737.08

In Stock

Quantity

1

Base Price: ₹ 50,737.08

GST (18%): ₹ 9,132.674

Total Price: ₹ 59,869.754

Antigen

Tyrosine Hydroxylase

Classification

Polyclonal

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.

P04177, P07101, P24529

Gene Symbols

TH

Immunogen

SDS-denatured, native rat tyrosine hydroxylase purified from pheochromocytoma

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Multi-species, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Immunohistochemistry, Western Blot

Conjugate

Unconjugated

Gene

TH

Gene Alias

dystonia 14; DYT14; DYT5b; EC 1.14.16.2; HGNC:11782; Th; TH isoform 3; TH isoform a; th1; TH-4; The; TY3H; TYH; TYH antibody; Tyrosine 3-hydroxylase; tyrosine 3-monooxygenase; tyrosine hydroxylase

Host Species

Sheep

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

21823, 25085, 7054

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • This antibody is specific for the ∽60 kDa Tyrosine Hydroxylase in Western blots of rat brain extracts
  • Tyrosine hydroxylase (TH) is an enzyme involved in the synthesis of catecholamine neurotransmitters dopamine, epinephrine, and norepinephrine
  • In all species, catecholamine synthesis is regulated by the interaction of TH with a cofactor, tetrahydrobiopterin (BH4)
  • BH4 binds to the TH catalytic domain, resulting in enzymatic activity
  • Unlike TH in non-primate species, four human TH mRNA splice variants (hTH1-hTH4) have been isolated
  • These variants are identical in their catalytic domain, but differ in their N-terminal, regulatory domains
  • TH is also responsible for the conversion of L-tyrosine to L-dopa
  • TH plays a key role in the physiology of adrenergic neurons
  • The role of TH in the synthesis of catecholamine neurotransmitters suggests a correlation between the enzyme and a number of neuropathogenic diseases including: Parkinson's disease, schizophrenia, Segawa syndrome, and dystonia, as well as a variety of cardiovascular diseases.

Compare Similar Items

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Thermo Scientific

PA14679

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Antigen:
Tyrosine Hydroxylase

Classification:
Polyclonal

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P04177, P07101, P24529

Gene Symbols:
TH

Immunogen:
SDS-denatured, native rat tyrosine hydroxylase purified from pheochromocytoma

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Multi-species, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Conjugate:
Unconjugated

Gene:
TH

Gene Alias:
dystonia 14; DYT14; DYT5b; EC 1.14.16.2; HGNC:11782; Th; TH isoform 3; TH isoform a; th1; TH-4; The; TY3H; TYH; TYH antibody; Tyrosine 3-hydroxylase; tyrosine 3-monooxygenase; tyrosine hydroxylase

Host Species:
Sheep

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
21823, 25085, 7054

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

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PA14733

--


Antigen:
Phospho-NMDAR2B (Ser1480)

Classification:
Polyclonal

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
Q00960, Q01097

Gene Symbols:
GRIN2B

Immunogen:
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser1480 of rat GRIN2B conjugated to KLH

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
GRIN2B

Gene Alias:
AW490526; EIEE27; GluN2B; GluRepsilon2; glutamate [NMDA] receptor subunit epsilon-2; glutamate ionotropic receptor NMDA type subunit 2B; glutamate receptor; glutamate receptor ionotropic, NMDA 2B; glutamate receptor subunit epsilon-2; glutamate receptor, ionotropic, NMDA2B; glutamate receptor, ionotropic, NMDA2B (epsilon 2); glutamate receptor, ionotropic, N-methyl D-aspartate 2B; GRIN 2B; GRIN2B; HGNC:4586; hNR 3; hNR3; LOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 2B; MGC142178; MGC142180; MRD6; Nmdar2b; NMDE2; NME2; N-methyl D-aspartate receptor 2B; N-methyl D-aspartate receptor subtype 2B; N-methyl-D-aspartate receptor subunit 2B; N-methyl-D-aspartate receptor subunit 3; NR2B; NR3

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14812, 24410

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

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PA14734

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Antigen:
Phospho-Parkin (Ser101)

Classification:
Polyclonal

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
O60260

Gene Symbols:
PRKN

Immunogen:
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser101 of human PARK2 conjugated to KLH

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
PRKN

Gene Alias:
AAN12155.1; AR-JP; CG10523; CG10523-PB; CG10523-PC; Dmel\CG10523; Dmel_CG10523; Dpark; dParkin; D-parkin; dpk; E3 ubiquitin ligase; E3 ubiquitin-protein ligase parkin; LPRS2; OTTHUMP00000017562; OTTHUMP00000017563; OTTHUMP00000017564; park; park1; PARK2; Parkin; parkin 2; parkin F; Parkin isoform 1; parkin protein; parkin RBR E3 ubiquitin protein ligase; Parkin RBR E3 ubiquitin-protein ligase; parkin variant SV5DEL; Parkinson disease (autosomal recessive, juvenile) 2, parkin; Parkinson disease protein 2; Parkinson juvenile disease protein 2; parkinson protein 2 E3 ubiquitin protein ligase; parkinson protein 2, E3 ubiquitin protein ligase; parkinson protein 2, E3 ubiquitin protein ligase (parkin); park-PB; park-PC; PDJ; PK; Prkn; SD01679

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5071

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PA14735

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Antigen:
Phospho-Parkin (Ser378)

Classification:
Polyclonal

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
O60260

Gene Symbols:
PRKN

Immunogen:
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser378 of human PARK2 conjugated to KLH

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
PRKN

Gene Alias:
AAN12155.1; AR-JP; CG10523; CG10523-PB; CG10523-PC; Dmel\CG10523; Dmel_CG10523; Dpark; dParkin; D-parkin; dpk; E3 ubiquitin ligase; E3 ubiquitin-protein ligase parkin; LPRS2; OTTHUMP00000017562; OTTHUMP00000017563; OTTHUMP00000017564; park; park1; PARK2; Parkin; parkin 2; parkin F; Parkin isoform 1; parkin protein; parkin RBR E3 ubiquitin protein ligase; Parkin RBR E3 ubiquitin-protein ligase; parkin variant SV5DEL; Parkinson disease (autosomal recessive, juvenile) 2, parkin; Parkinson disease protein 2; Parkinson juvenile disease protein 2; parkinson protein 2 E3 ubiquitin protein ligase; parkinson protein 2, E3 ubiquitin protein ligase; parkinson protein 2, E3 ubiquitin protein ligase (parkin); park-PB; park-PC; PDJ; PK; Prkn; SD01679

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5071

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid