PA540200

Phospho-HGS (Tyr216) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA540200-Each-of-1 In Stock ₹ 44,191.74

PA540200 - Each of 1

₹ 44,191.74

In Stock

Quantity

1

Base Price: ₹ 44,191.74

GST (18%): ₹ 7,954.513

Total Price: ₹ 52,146.253

Antigen

Phospho-HGS (Tyr216)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

HGS

Gene Alias

hepatocyte growth factor-regulated tyrosine kinase substrate; HGF-regulated tyrosine kinase substrate; HGNC:4897; Hgr; Hgs; Hrs; Hrs2; human growth factor-regulated tyrosine kinase substrate; protein pp110; SNAP-25-interacting protein Hrs-2; ZFYVE8

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

15239, 56084, 9146

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

ELISA, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O14964, Q99LI8, Q9JJ50

Gene Symbols

HGS

Immunogen

Synthesized peptide derived from human Hrs around the phosphorylation site of Y216.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • This antibody is predicted to react with mouse and rat based on sequence homology
  • HGS is involved in intracellular signal transduction mediated by cytokines and growth factors
  • When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF
  • It could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin
  • HGS may concentrate ubiquitinated receptors within clathrin-coated regions
  • It is involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM
  • This complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes
  • HGS may contribute to the efficient recruitment of SMADs to the activin receptor complex.

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Thermo Scientific

PA540200

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Antigen:
Phospho-HGS (Tyr216)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HGS

Gene Alias:
hepatocyte growth factor-regulated tyrosine kinase substrate; HGF-regulated tyrosine kinase substrate; HGNC:4897; Hgr; Hgs; Hrs; Hrs2; human growth factor-regulated tyrosine kinase substrate; protein pp110; SNAP-25-interacting protein Hrs-2; ZFYVE8

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15239, 56084, 9146

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O14964, Q99LI8, Q9JJ50

Gene Symbols:
HGS

Immunogen:
Synthesized peptide derived from human Hrs around the phosphorylation site of Y216.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA540204

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Antigen:
Phospho-MAP2K4 (Ser80)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAP2K4

Gene Alias:
C-JUN N-terminal kinase kinase 1; dual specificity mitogen-activated protein kinase kinase 2; dual specificity mitogen-activated protein kinase kinase 4; dual specificity mitogen-activated protein kinase kinase 4; dual specificity mitogen-activated protein kinase kinase 4a; JNK kinase 1; JNK-activated kinase 1; JNK-activating kinase 1; JNKK; JNKK 1; JNKK1; MAP kinase activator 2; MAP kinase kinase 4; Map2k4; map2k4.L; map2k4a; map2k4-a; map2k4-b; MAP2K4delta; MAPK/ERK kinase 4; MAPKK 4; MAPKK4; MEK 4; MEK4; mitogen activated protein kinase kinase 4; mitogen activated protein kinase kinase 4, variant 1; mitogen-activated protein kinase kinase 4; mitogen-activated protein kinase kinase 4 L homeolog; mitogen-activated protein kinase kinase 4a; MKK4; mkk4a; MKK4A-l; PRKMK4; SAPK kinase 1; SAPK/ERK kinase 1; SAPK/Erk/kinase 1; SAPKK1; SAPKK-1; Sek1; Serk1; Skk1; Stress-activated protein kinase kinase 1; XELAEV_18044157mg; XMEK2; zgc:136500; zMKK4 protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
26398, 287398, 6416

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P45985, P47809

Gene Symbols:
MAP2K4

Immunogen:
Synthesized peptide derived from human MEK-4 around the phosphorylation site of S80.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA540205

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Antigen:
Phospho-ErbB2 (HER-2) (Tyr1221, Tyr1222)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ERBB2

Gene Alias:
avian erythroblastosis oncogene B 2; Avian erythroblastosis viral (v-erb-B2) oncogene homologue 2 (neuro/glioblastoma derived oncogene homolog); CD antigen CD340; CD340; c-erb B2/neu protein; c-erbB2; C-erbB-2; c-neu; epidermal growth factor receptor-related protein; erbb 2; ERBB2; erb-b2; Erbb-2; ErbB2 (pTyr1139); ErbB2 (pY1139); ErbB2 phospho Y1139; erb-b2 receptor tyrosine kinase 2; her 2; HER2; HER-2; HER-2/neu; herstatin; human epidermal growth factor receptor 2; Kiaa3023; metas; Metastatic lymph node gene 19 protein; mKIAA3023; MLN 19; MLN19; NEU; Neu oncogene; NEU proto-oncogene; neuro/glioblastoma derived oncogene homolog; neuroblastoma/glioblastoma derived oncogene homolog; NGL; p185erbB2; p185neu; phospho ErbB2; proto-oncogene c-ErbB-2; Proto-oncogene Neu; receptor tyrosine-protein kinase erbB-2; TKR1; Tyrosine kinase-type cell surface receptor HER2; v-erb-b2 avian erythroblastic leukemia viral oncogene 2; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2; v-erb-b2 avian erythroblastic leukemia viral oncoprotein 2; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13866, 2064, 24337

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P04626, P06494, P70424

Gene Symbols:
ERBB2

Immunogen:
Synthesized peptide derived from human Neu around the phosphorylation site of Y1221/Y1222.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA540206

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Antigen:
Phospho-Stathmin 1 (Ser16)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Stmn1

Gene Alias:
19k; C1orf215; I79_017954; Lag; LAP18; leukemia associated phosphoprotein p18; leukemia-associated cytosolic phosphoprotein stathmin; leukemia-associated gene protein; Leukemia-associated phosphoprotein p18; metablastin; Oncoprotein 18; Op18; OTTHUMP00000008529; OTTHUMP00000008531; P18; P19; phosphoprotein 19; phosphoprotein p19; Pig; pp17; Pp18; Pp19; Pr22; Pr22 protein; Prosolin; Protein Pr22; RP1-125I3.5; SMN; Stathmin; stathmin 1; stathmin 1 variant; stathmin 1/oncoprotein 18; Stmn1; STN1; testicular tissue protein Li 189; transmembrane protein C1orf215

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16765, 29332, 3925

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P13668, P16949, P54227

Gene Symbols:
Stmn1

Immunogen:
Synthesized peptide derived from human Op18 around the phosphorylation site of S16.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG