PA540280

Phospho-IRS1 (Ser323) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PA540280-Each-of-1 In Stock ₹ 44,705.10

PA540280 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Phospho-IRS1 (Ser323)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

IRS1

Gene Alias

G972R; HIRS-1; Insulin receptor substrate 1; IRS1; IRS-1; IRS1IRM; pp185

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16367, 25467, 3667

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P35568, P35569, P35570

Gene Symbols

IRS1

Immunogen

Synthesized peptide derived from human IRS-1 around the phosphorylation site of S323.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Non-human Primate, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • This antibody is predicted to react with mouse, rat, and monkey based on sequence homology
  • IRS-1, a major substrate of the insulin receptor, is phosphorylated in response to stimulation of cells by insulin, insulin-like growth factor 1 (IGF-1) and interleukin 4 (IL-4)
  • IRS-1 is phosphorylated on serine, threonine and tyrosine residues in a variety of tissues
  • An insulin-sensitive serine/threonine kinase casein kinase II mediates a portion of the insulin-stimulated serine/threonine phosphorylation of overexpressed IRS-1 in vivo
  • Thr 502 is identified as the major casein kinase II-catalyzed phosphorylation site in rat IRS-1, and Ser 99 is an additional phosphorylation site catalyzed by casein kinase II
  • Thus, casein kinase II-catalyzed phosphorylation of IRS-1 may be a component of the intracellular insulin signaling cascade
  • IRS-1 contains three putative binding sites for 14-3-3 (Ser 270, Ser 374 and Ser 641) and the motif around Ser 270 is located in the phosphortyrosine binding domain of IRS-1, which is responsible for the interaction with the insulin receptor.

Compare Similar Items

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Thermo Scientific

PA540280

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Antigen:
Phospho-IRS1 (Ser323)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IRS1

Gene Alias:
G972R; HIRS-1; Insulin receptor substrate 1; IRS1; IRS-1; IRS1IRM; pp185

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16367, 25467, 3667

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P35568, P35569, P35570

Gene Symbols:
IRS1

Immunogen:
Synthesized peptide derived from human IRS-1 around the phosphorylation site of S323.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

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PA540284

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Antigen:
Phospho-Calmodulin (Thr80, Ser82)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CALM3

Gene Alias:
1500001E21Rik; 2310037J09Rik; AI256814; AI327027; AI461935; AI649108; AL024000; AL024017; AY314008; calcium binding gene, DD112; calcium-binding protein Dd112; CALM; CALM 1; CALM1; CALM2; Calm3; Calm4; Calm5; CALML2; Calmodulin; calmodulin 1; calmodulin 1 (phosphorylase kinase, delta); calmodulin 2; calmodulin 2 (phosphorylase kinase, delta); calmodulin 3; calmodulin 3 (phosphorylase kinase, delta); calmodulin 4; calmodulin 5; Calmodulin III; calmodulin-1; Calmodulin-2; calmodulin-3; Calmodulin-4; calmodulin-like; calmodulin-like protein; calmodulin-like protein (neoCaM); caM; CAM1; Cam2; CAM3; CaMA; Camb; CamC; CaMI; CAMII; CAMIII; CPVT4; DD112; DD132; DD312; epididymis secretory protein Li 72; HEL-S-72; hypothetical protein; LP7057 protein; LQT14; LQT15; MGC128137 protein; neo-calmodulin; NeoCaM; PHKD; PHKD2; PHKD3; phosphorylase kinase delta; phosphorylase kinase subunit delta; phosphorylase kinase, delta subunit; prepro-calmodulin 1; prepro-calmodulin 2; prepro-calmodulin 3; R75142; RNCAMIII; Scarf; Scarf2; similar to calmodulin; skin calmodulin-related factor

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12313, 12314, 12315, 24242, 24244, 494124, 50663, 801, 805, 80796, 808

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P0DP23, P0DP24, P0DP25, P0DP26, P0DP27, P0DP28, P0DP29, P0DP30, P0DP31, Q9JM83

Gene Symbols:
Calm1, Calm2, CALM3, CALM4, CALM5

Immunogen:
Synthesized peptide derived from human Calmodulin around the phosphorylation site of T80/S82.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PA540285

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Antigen:
Phospho-CXCR4 (Ser339)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cxcr4

Gene Alias:
b2b220Clo; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; CD antigen CD184; CD184; CD184 antigen; chemokine (C-X-C motif) receptor 4; chemokine (C-X-C) receptor 4; chemokine receptor; chemokine receptor (LCR1); chemokine receptor 4; chemokine receptor CXCR4; Cmkar4; CXC; CXC chemokine receptor; C-X-C chemokine receptor type 4; CXC motif chemokine; C-X-C motif chemokine receptor 4; CXCR4; CXC-R4; CXCR-4; D2S201E; FB22; Fusin; HM89; HSY3RR; HUMSTR; LAP3; LAP-3; LCR1; LESTR; Leukocyte-derived seven transmembrane domain receptor; leukocyte-expressed seven-transmembrane-domain; lipopolysaccharide-associated protein 3; LPS-associated protein 3; neuropeptide Y receptor Y3; neuropeptide Y3 receptor; NPY3R; NPYR; NPYRL; NPYY3R; PB-CKR; PBSF/SDF-1; pre-B-cell-derived chemokine receptor; SDF-1 receptor; Sdf1r; seven transmembrane helix receptor; seven-transmembrane-segment receptor, spleen; stromal cell-derived factor 1 receptor; WHIM; WHIMS

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12767, 60628, 7852

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot, Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O08565, P61073, P70658

Gene Symbols:
Cxcr4

Immunogen:
Synthesized peptide derived from human Fusin around the phosphorylation site of S339.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

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PA540287

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Antigen:
Phospho-ELK3 (Ser357)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ELK3

Gene Alias:
D430049E23Rik; ELK3; ELK3, ETS transcription factor; ELK3, ETS-domain protein; ELK3, ETS-domain protein (SRF accessory protein 2); ELK3, member of ETS oncogene family; Erp; Etrp; ETS domain-containing protein Elk-3; ETS transcription factor ELK3; ETS-domain protein ELK-3; ETS-related protein ERP; ETS-related protein NET; Net; SAP2; Sap-2; Serum response factor accessory protein 2; si:ch211-172b12.2; si:dkey-201e17.1; SRF accessory protein 2; zgc:198153; zgc:198183

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13713, 2004

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P41970, P41971

Gene Symbols:
ELK3

Immunogen:
Synthesized peptide derived from human Net around the phosphorylation site of S357.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate

Product Type:
Antibody

Isotype:
IgG