PA540285

Phospho-CXCR4 (Ser339) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA540285-Each-of-1 In Stock ₹ 46,929.66

PA540285 - Each of 1

₹ 46,929.66

In Stock

Quantity

1

Base Price: ₹ 46,929.66

GST (18%): ₹ 8,447.339

Total Price: ₹ 55,376.999

Antigen

Phospho-CXCR4 (Ser339)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Cxcr4

Gene Alias

b2b220Clo; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; CD antigen CD184; CD184; CD184 antigen; chemokine (C-X-C motif) receptor 4; chemokine (C-X-C) receptor 4; chemokine receptor; chemokine receptor (LCR1); chemokine receptor 4; chemokine receptor CXCR4; Cmkar4; CXC; CXC chemokine receptor; C-X-C chemokine receptor type 4; CXC motif chemokine; C-X-C motif chemokine receptor 4; CXCR4; CXC-R4; CXCR-4; D2S201E; FB22; Fusin; HM89; HSY3RR; HUMSTR; LAP3; LAP-3; LCR1; LESTR; Leukocyte-derived seven transmembrane domain receptor; leukocyte-expressed seven-transmembrane-domain; lipopolysaccharide-associated protein 3; LPS-associated protein 3; neuropeptide Y receptor Y3; neuropeptide Y3 receptor; NPY3R; NPYR; NPYRL; NPYY3R; PB-CKR; PBSF/SDF-1; pre-B-cell-derived chemokine receptor; SDF-1 receptor; Sdf1r; seven transmembrane helix receptor; seven-transmembrane-segment receptor, spleen; stromal cell-derived factor 1 receptor; WHIM; WHIMS

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12767, 60628, 7852

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunohistochemistry, Western Blot, Immunohistochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O08565, P61073, P70658

Gene Symbols

Cxcr4

Immunogen

Synthesized peptide derived from human Fusin around the phosphorylation site of S339.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Non-human Primate, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • This antibody is predicted to react with mouse, rat, and monkey based on sequence homology
  • CXCR4 (Fusin, LESTR, HUMSTR) is a member of the G-protein-coupled chemokine receptor family with seven membrane-spanning domains, and functions as a co-receptor for X4 HIV-1 entry into CD4+ cells
  • CXCR4 has been proved to be the co-receptor for HIV-2's binding to CD4 through envelope glycoprotein gp 120 and promotes Env-mediated fusion of the virus
  • In other cases, CXCR4 can even function as the only receptor for HIV-2's binding to the CD4 host cells
  • CXCR4 is the receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation
  • CXCR4 acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels
  • Also, CXCR4 is involved in hematopoiesis and in cardiac ventricular septum formation, and plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells
  • In the CNS, CXCR4 could mediate hippocampal-neuron survival and is involved in cerebellar development
  • CXCR4 binds bacterial lipopolysaccharide (LPS) and mediates LPS-induced inflammatory response, including TNF secretion by monocytes
  • Antibodies to CXCR4 block HIV-1 and HIV-2 fusion and infection of human target cells
  • The amino-terminal domain and the second extracellular loop of CXCR4 serve as HIV biding sites.

Compare Similar Items

Show Difference

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Thermo Scientific

PA540285

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Antigen:
Phospho-CXCR4 (Ser339)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cxcr4

Gene Alias:
b2b220Clo; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; CD antigen CD184; CD184; CD184 antigen; chemokine (C-X-C motif) receptor 4; chemokine (C-X-C) receptor 4; chemokine receptor; chemokine receptor (LCR1); chemokine receptor 4; chemokine receptor CXCR4; Cmkar4; CXC; CXC chemokine receptor; C-X-C chemokine receptor type 4; CXC motif chemokine; C-X-C motif chemokine receptor 4; CXCR4; CXC-R4; CXCR-4; D2S201E; FB22; Fusin; HM89; HSY3RR; HUMSTR; LAP3; LAP-3; LCR1; LESTR; Leukocyte-derived seven transmembrane domain receptor; leukocyte-expressed seven-transmembrane-domain; lipopolysaccharide-associated protein 3; LPS-associated protein 3; neuropeptide Y receptor Y3; neuropeptide Y3 receptor; NPY3R; NPYR; NPYRL; NPYY3R; PB-CKR; PBSF/SDF-1; pre-B-cell-derived chemokine receptor; SDF-1 receptor; Sdf1r; seven transmembrane helix receptor; seven-transmembrane-segment receptor, spleen; stromal cell-derived factor 1 receptor; WHIM; WHIMS

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12767, 60628, 7852

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot, Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O08565, P61073, P70658

Gene Symbols:
Cxcr4

Immunogen:
Synthesized peptide derived from human Fusin around the phosphorylation site of S339.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

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PA540287

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Antigen:
Phospho-ELK3 (Ser357)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ELK3

Gene Alias:
D430049E23Rik; ELK3; ELK3, ETS transcription factor; ELK3, ETS-domain protein; ELK3, ETS-domain protein (SRF accessory protein 2); ELK3, member of ETS oncogene family; Erp; Etrp; ETS domain-containing protein Elk-3; ETS transcription factor ELK3; ETS-domain protein ELK-3; ETS-related protein ERP; ETS-related protein NET; Net; SAP2; Sap-2; Serum response factor accessory protein 2; si:ch211-172b12.2; si:dkey-201e17.1; SRF accessory protein 2; zgc:198153; zgc:198183

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13713, 2004

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P41970, P41971

Gene Symbols:
ELK3

Immunogen:
Synthesized peptide derived from human Net around the phosphorylation site of S357.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate

Product Type:
Antibody

Isotype:
IgG

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PA540291

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Antigen:
Phospho-OPRM1 (Ser375)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
OPRM1

Gene Alias:
hMOP; KIAA0403; LMOR; MOP; MOP receptor; MOP-R; Mor; MOR1; M-OR-1; MOR-1; MOR-1C; MOR-1O; MORA; Mu opiate receptor; mu opioid receptor; mu opioid receptor hMOR-1a; mu opioid receptor splice variant mMOR-1Z; mu opioid receptor splice variant rMOR-1S; mu opioid receptor splice variant rMOR-1Z; mu-opioid receptor; muOR; MUOR1; mu-type opioid receptor; Opioid mu receptor; Opioid Receptor; opioid receptor B; opioid receptor mu 1; opioid receptor, mu 1; OPRM; Oprm1; Oprrm1; OTTHUMP00000017463; Ror-b

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18390, 25601, 4988

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P33535, P35372, P42866

Gene Symbols:
OPRM1

Immunogen:
Synthesized peptide derived from human MOR-1 around the phosphorylation site of S375.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PA540292

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Antigen:
Phospho-ITK (Tyr512)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ITK

Gene Alias:
EMT; homolog of mouse T-cell itk/tsk; IL2 inducible T cell kinase; IL2 inducible T-cell kinase; IL-2-inducible T cell kinase; IL-2-inducible T-cell kinase; IL2-inducible T-cell kinase; interleukin-2-inducible T cell kinase; interleukin-2-inducible T-cell kinase; ITK; Kinase EMT; kinase TLK; LPFS1; LYK; MGC126257; MGC126258; PSCTK2; T-cell-specific kinase; Tcsk; Tlk; Tsk; Tyrosine-protein kinase ITK/TSK; tyrosine-protein kinase LYK

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16428, 3702

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q03526, Q08881

Gene Symbols:
ITK

Immunogen:
Synthesized peptide derived from human Emt around the phosphorylation site of Y512.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG