FERMA548993
Complement C3b Monoclonal Antibody (2B10B9B2), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FERMA548993-Each-of-1 | In Stock | ₹ 54,073.92 |
FERMA548993 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 54,073.92
GST (18%): ₹ 9,733.306
Total Price: ₹ 63,807.226
Antigen
Complement C3b
Classification
Monoclonal
Conjugate
Unconjugated
Gene
C3
Gene Alias
Acylation stimulating protein; acylation-stimulating protein cleavage product; AHUS5; AI255234; ARMD9; ASP; C3; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; C3a; C3a anaphylatoxin; C3adesArg; C3b; C3bc; C3-beta-c; Complement C3; Complement C3 alpha chain; Complement C3 beta chain; Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3c alpha' chain fragment 2; Complement C3d fragment; Complement C3dg fragment; Complement C3f fragment; Complement C3g fragment; complement component 3; complement component C3a; complement component C3b; CPAMD1; ENCF-1; ENCF-2; epididymis secretory sperm binding protein Li 62p; HEL-S-62p; HSE-MSF; iC3b; Neutrophil chemotactic factor-1; Neutrophil chemotactic factor-2; Plp; prepro-C3
Host Species
Mouse
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Rat
Form
Liquid
Applications
Inhibition Assays, Western Blot
Clone
2B10B9B2
Formulation
tissue culture supernatant with 0.02% sodium azide
Gene Accession No.
P01026
Gene Symbols
C3
Immunogen
The monoclonal antibody 2B10B9B2 reacts with an epitope on C3b
Regulatory Status
RUO
Gene ID (Entrez)
24232
Content And Storage
4° C
Isotype
IgM
Related Products
Description
- The antibody reacts both with intact C3 and C3b
- Inactive complement component 3b (iC3b) is a 42kDa neoantigen present in blood serum
- Cleavage of C3b into iC3b by the protease factor I, in the presence of cofactors, changes the structure and resulting binding properties, preventing binding by complement factor B and properdin
- This prevents further progression of the complement pathway, providing another mechanism by which the complement pathway may be regulated
- iC3b is thought to play a role in inducing tolerance, binding complement receptor type 3 on antigen presenting cells and stimulating them to produce transforming growth factor beta2 and interleukin-10
- It is thought to stimulate B-cells via the CD21 receptor providing a link between the innate and adaptive immune responses
- Additionally iC3b acts as an opsonin which is recognised by complement receptor 3 expressed on leukocytes or complement receptor of the immunoglobulin superfamily (CRIg) on Kupffer cells, stimulating phagocytosis of the tagged cells
- iC3b levels are often elevated in diseases such as Systemic Lupus Erythematosis and Rheumatoid arthritis.
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Antigen: Complement C3b
Classification: Monoclonal
Conjugate: Unconjugated
Gene: C3
Gene Alias: Acylation stimulating protein; acylation-stimulating protein cleavage product; AHUS5; AI255234; ARMD9; ASP; C3; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; C3a; C3a anaphylatoxin; C3adesArg; C3b; C3bc; C3-beta-c; Complement C3; Complement C3 alpha chain; Complement C3 beta chain; Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3c alpha' chain fragment 2; Complement C3d fragment; Complement C3dg fragment; Complement C3f fragment; Complement C3g fragment; complement component 3; complement component C3a; complement component C3b; CPAMD1; ENCF-1; ENCF-2; epididymis secretory sperm binding protein Li 62p; HEL-S-62p; HSE-MSF; iC3b; Neutrophil chemotactic factor-1; Neutrophil chemotactic factor-2; Plp; prepro-C3
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Rat
Form: Liquid
Applications: Inhibition Assays, Western Blot
Clone: 2B10B9B2
Formulation: tissue culture supernatant with 0.02% sodium azide
Gene Accession No.: P01026
Gene Symbols: C3
Immunogen: The monoclonal antibody 2B10B9B2 reacts with an epitope on C3b
Regulatory Status: RUO
Gene ID (Entrez): 24232
Content And Storage: 4° C
Isotype: IgM
Antigen:
Complement C3b
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
C3
Gene Alias:
Acylation stimulating protein; acylation-stimulating protein cleavage product; AHUS5; AI255234; ARMD9; ASP; C3; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; C3a; C3a anaphylatoxin; C3adesArg; C3b; C3bc; C3-beta-c; Complement C3; Complement C3 alpha chain; Complement C3 beta chain; Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3c alpha' chain fragment 2; Complement C3d fragment; Complement C3dg fragment; Complement C3f fragment; Complement C3g fragment; complement component 3; complement component C3a; complement component C3b; CPAMD1; ENCF-1; ENCF-2; epididymis secretory sperm binding protein Li 62p; HEL-S-62p; HSE-MSF; iC3b; Neutrophil chemotactic factor-1; Neutrophil chemotactic factor-2; Plp; prepro-C3
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Rat
Form:
Liquid
Applications:
Inhibition Assays, Western Blot
Clone:
2B10B9B2
Formulation:
tissue culture supernatant with 0.02% sodium azide
Gene Accession No.:
P01026
Gene Symbols:
C3
Immunogen:
The monoclonal antibody 2B10B9B2 reacts with an epitope on C3b
Regulatory Status:
RUO
Gene ID (Entrez):
24232
Content And Storage:
4° C
Isotype:
IgM
Antigen: C3a Receptor
Classification: Monoclonal
Conjugate: Unconjugated
Gene: C3ar1
Gene Alias: anaphylatoxin C3a receptor; AZ3B; C3a anaphylatoxin chemotactic receptor; C3a receptor; C3AR; C3a-R; C3AR1; C3r1; complement component 3 receptor 1; complement component 3a receptor 1; HNFAG09
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Form: Liquid
Applications: Flow Cytometry, Immunohistochemistry (Frozen)
Clone: 14D4
Formulation: PBS with 0.1% BSA and 0.02% sodium azide
Gene Accession No.: O09047
Gene Symbols: C3ar1
Immunogen: RBL-2H3 transfectants expressing mouse C3aR
Regulatory Status: RUO
Gene ID (Entrez): 12267
Content And Storage: 4° C
Isotype: IgG2a
Antigen:
C3a Receptor
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
C3ar1
Gene Alias:
anaphylatoxin C3a receptor; AZ3B; C3a anaphylatoxin chemotactic receptor; C3a receptor; C3AR; C3a-R; C3AR1; C3r1; complement component 3 receptor 1; complement component 3a receptor 1; HNFAG09
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Form:
Liquid
Applications:
Flow Cytometry, Immunohistochemistry (Frozen)
Clone:
14D4
Formulation:
PBS with 0.1% BSA and 0.02% sodium azide
Gene Accession No.:
O09047
Gene Symbols:
C3ar1
Immunogen:
RBL-2H3 transfectants expressing mouse C3aR
Regulatory Status:
RUO
Gene ID (Entrez):
12267
Content And Storage:
4° C
Isotype:
IgG2a
Antigen: Complement C4d
Classification: Monoclonal
Conjugate: Unconjugated
Gene: C4A
Gene Alias: acidic C4; acidic complement C4; Basic complement C4; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3; C4; c4 complement; C4A; C4a anaphylatoxin; C4A2; C4A3; C4A4; C4A6; C4AD; C4B; C4B_2; C4B1; C4B12; C4B2; C4B3; C4B5; C4b-A; C4b-B; C4BD; C4D; C4d-A; C4d-B; C4F; C4S; CH; Chido form of C4; CO4; Complement C4 beta chain; Complement C4 gamma chain; Complement C4-A; Complement C4-A alpha chain; Complement C4-B; Complement C4-B alpha chain; complement C4B1a; complement component 4A (Rodgers blood group); complement component 4B (Chido blood group); CPAMD2; CPAMD3; DADB-112B14.11; FLJ60561; MGC164979; MHC class III region complement; RG; Rodgers form of C4
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Flow Cytometry, Immunohistochemistry (Frozen), Inhibition Assays, Western Blot
Clone: 12D11
Formulation: PBS with 0.1% BSA and 0.02% sodium azide
Gene Accession No.: P0C0L4, P0C0L5
Gene Symbols: C4A, C4B
Immunogen: The monoclonal antibody 12D11 recognizes an epitope on the alpha 2 chain of human C4d.
Regulatory Status: RUO
Gene ID (Entrez): 100293534, 720, 721
Content And Storage: 4° C
Isotype: IgG1
Antigen:
Complement C4d
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
C4A
Gene Alias:
acidic C4; acidic complement C4; Basic complement C4; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3; C4; c4 complement; C4A; C4a anaphylatoxin; C4A2; C4A3; C4A4; C4A6; C4AD; C4B; C4B_2; C4B1; C4B12; C4B2; C4B3; C4B5; C4b-A; C4b-B; C4BD; C4D; C4d-A; C4d-B; C4F; C4S; CH; Chido form of C4; CO4; Complement C4 beta chain; Complement C4 gamma chain; Complement C4-A; Complement C4-A alpha chain; Complement C4-B; Complement C4-B alpha chain; complement C4B1a; complement component 4A (Rodgers blood group); complement component 4B (Chido blood group); CPAMD2; CPAMD3; DADB-112B14.11; FLJ60561; MGC164979; MHC class III region complement; RG; Rodgers form of C4
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Inhibition Assays, Western Blot
Clone:
12D11
Formulation:
PBS with 0.1% BSA and 0.02% sodium azide
Gene Accession No.:
P0C0L4, P0C0L5
Gene Symbols:
C4A, C4B
Immunogen:
The monoclonal antibody 12D11 recognizes an epitope on the alpha 2 chain of human C4d.
Regulatory Status:
RUO
Gene ID (Entrez):
100293534, 720, 721
Content And Storage:
4° C
Isotype:
IgG1
Antigen: Complement C4d
Classification: Monoclonal
Conjugate: Unconjugated
Gene: C4B
Gene Alias: acidic C4; acidic complement C4; Basic complement C4; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3; C4; c4 complement; C4A; C4a anaphylatoxin; C4A2; C4A3; C4A4; C4A6; C4AD; C4B; C4B_2; C4B1; C4B12; C4B2; C4B3; C4B5; C4b-A; C4b-B; C4BD; C4D; C4d-A; C4d-B; C4F; C4S; CH; Chido form of C4; CO4; Complement C4 beta chain; Complement C4 gamma chain; Complement C4-A; Complement C4-A alpha chain; Complement C4-B; Complement C4-B alpha chain; complement C4B1a; complement component 4A (Rodgers blood group); complement component 4B (Chido blood group); CPAMD2; CPAMD3; DADB-112B14.11; FLJ60561; MGC164979; MHC class III region complement; RG; Rodgers form of C4
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Immunohistochemistry (Frozen), Inhibition Assays, Western Blot
Clone: 7H4
Formulation: PBS with 0.1% BSA and 0.02% sodium azide
Gene Accession No.: P0C0L4, P0C0L5
Gene Symbols: C4A, C4B
Immunogen: The monoclonal antibody 7H4 recognizes an epitope on the alpha 2 chain of human C4d
Regulatory Status: RUO
Gene ID (Entrez): 100293534, 720, 721
Content And Storage: 4° C
Isotype: IgG1
Antigen:
Complement C4d
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
C4B
Gene Alias:
acidic C4; acidic complement C4; Basic complement C4; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3; C4; c4 complement; C4A; C4a anaphylatoxin; C4A2; C4A3; C4A4; C4A6; C4AD; C4B; C4B_2; C4B1; C4B12; C4B2; C4B3; C4B5; C4b-A; C4b-B; C4BD; C4D; C4d-A; C4d-B; C4F; C4S; CH; Chido form of C4; CO4; Complement C4 beta chain; Complement C4 gamma chain; Complement C4-A; Complement C4-A alpha chain; Complement C4-B; Complement C4-B alpha chain; complement C4B1a; complement component 4A (Rodgers blood group); complement component 4B (Chido blood group); CPAMD2; CPAMD3; DADB-112B14.11; FLJ60561; MGC164979; MHC class III region complement; RG; Rodgers form of C4
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Immunohistochemistry (Frozen), Inhibition Assays, Western Blot
Clone:
7H4
Formulation:
PBS with 0.1% BSA and 0.02% sodium azide
Gene Accession No.:
P0C0L4, P0C0L5
Gene Symbols:
C4A, C4B
Immunogen:
The monoclonal antibody 7H4 recognizes an epitope on the alpha 2 chain of human C4d
Regulatory Status:
RUO
Gene ID (Entrez):
100293534, 720, 721
Content And Storage:
4° C
Isotype:
IgG1