FERMA549020

CD59 Monoclonal Antibody (7A6), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FERMA549020-Each-of-1 In Stock ₹ 44,106.18

FERMA549020 - Each of 1

₹ 44,106.18

In Stock

Quantity

1

Base Price: ₹ 44,106.18

GST (18%): ₹ 7,939.112

Total Price: ₹ 52,045.292

Antigen

CD59

Classification

Monoclonal

Concentration

100 μg/mL

Formulation

PBS with 0.1% BSA and no preservative

Gene Accession No.

O55186, P58019

Gene Symbols

Cd59a, Cd59b

Immunogen

mCD59a-Fc

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse

Form

Liquid

Applications

Flow Cytometry, Functional Assay, Immunocytochemistry, Immunohistochemistry (Frozen), Inhibition Assays, Western Blot

Clone

7A6

Conjugate

Unconjugated

Gene

Cd59b

Gene Alias

16.3A5; 1F5; 1F5 antigen; 20 kDa homologous restriction factor; AA987121; Cb59b molecule; CD59; CD59 antigen; CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344); CD59 glycoprotein; CD59 molecule; CD59 molecule (CD59 blood group); CD59 molecule, complement regulatory protein; Cd59a; CD59a antigen; CD59A glycoprotein; Cd59b; CD59b antigen; CD59B glycoprotein; CD59b moleucle, complement regulatory protein; complement inhibitor CD59; complement regulatory protein; EJ16; EJ30; EL32; G344; HRF20; HRF-20; human leukocyte antigen MIC11; Ly-6-like protein; lymphocytic antigen CD59/MEM43; MACIF; MAC-inhibitory protein; MACIP; MAC-IP; MEM43; MEM43 antigen; membrane attack complex (MAC) inhibition factor; membrane attack complex inhibition factor; Membrane inhibitor of reactive lysis; MIC11; MIN1; MIN2; MIN3; MIRL; MSK21; p18-20; protectin; surface anitgen recognized by monoclonal antibody 16.3A5; T cell-activating protein

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

12509, 333883

Content And Storage

4° C

Isotype

IgG1

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Description

  • CD59 (Protectin) is a small (18-20 kDa) GPI-anchored ubiquitously expressed inhibitor of the membrane attack complex (MAC)
  • CD59 is the key regulator that preserves the autologous cells from terminal effector mechanism of the complement cascade
  • CD59 also associates with C5b-8 complex and counteracts appropriate formation of cytolytic pore within the plasma membrane
  • Further, CD59 is a low-affinity ligand of human CD2, causes T cell costimulation, and is involved in lymphocyte signal transduction
  • CD59 is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation
  • Mutations in this gene cause CD59 deficiency, a disease involving hemolytic anemia, thrombosis, and cerebral infarction
  • Multiple alternatively spliced transcript variants of CD59 have been identified.

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Show Difference

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FERMA549020

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Antigen:
CD59

Classification:
Monoclonal

Concentration:
100 μg/mL

Formulation:
PBS with 0.1% BSA and no preservative

Gene Accession No.:
O55186, P58019

Gene Symbols:
Cd59a, Cd59b

Immunogen:
mCD59a-Fc

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Liquid

Applications:
Flow Cytometry, Functional Assay, Immunocytochemistry, Immunohistochemistry (Frozen), Inhibition Assays, Western Blot

Clone:
7A6

Conjugate:
Unconjugated

Gene:
Cd59b

Gene Alias:
16.3A5; 1F5; 1F5 antigen; 20 kDa homologous restriction factor; AA987121; Cb59b molecule; CD59; CD59 antigen; CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344); CD59 glycoprotein; CD59 molecule; CD59 molecule (CD59 blood group); CD59 molecule, complement regulatory protein; Cd59a; CD59a antigen; CD59A glycoprotein; Cd59b; CD59b antigen; CD59B glycoprotein; CD59b moleucle, complement regulatory protein; complement inhibitor CD59; complement regulatory protein; EJ16; EJ30; EL32; G344; HRF20; HRF-20; human leukocyte antigen MIC11; Ly-6-like protein; lymphocytic antigen CD59/MEM43; MACIF; MAC-inhibitory protein; MACIP; MAC-IP; MEM43; MEM43 antigen; membrane attack complex (MAC) inhibition factor; membrane attack complex inhibition factor; Membrane inhibitor of reactive lysis; MIC11; MIN1; MIN2; MIN3; MIRL; MSK21; p18-20; protectin; surface anitgen recognized by monoclonal antibody 16.3A5; T cell-activating protein

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
12509, 333883

Content And Storage:
4° C

Isotype:
IgG1

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FERMA549022

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Antigen:
CD8

Classification:
Monoclonal

Concentration:
100 μg/mL

Formulation:
PBS with 50% glycerol and 0.01% sodium azide

Gene Accession No.:
P05541, P07725

Gene Symbols:
Cd8a, CD8B

Immunogen:
15-11C5 is derived from hybridization of mouse SP2/0 myeloma cells with spleen cells from Balb/c mice immunized with WAG/Rij spleen cells.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Rat

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry (Frozen)

Clone:
15-11C5

Conjugate:
Unconjugated

Gene:
CD8B

Gene Alias:
BB154331; CD8; CD8 alpha; CD8 alpha chain; CD8 alpha chain precursor; CD8 antigen; CD8 antigen 32 kDa chain; CD8 antigen 37 kDa chain; CD8 antigen alpha polypeptide; CD8 antigen alpha protein; CD8 antigen alpha protein precursor; CD8 antigen alpha-chain; CD8 antigen beta polypeptide; CD8 antigen beta polypeptide precursor; CD8 antigen beta-chain; CD8 antigen, alpha chain; CD8 antigen, alpha polypeptide; CD8 antigen, alpha polypeptide (p32); CD8 antigen, alpha-chain; CD8 antigen, beta chain; CD8 antigen, beta chain 1; CD8 antigen, beta polypeptide; CD8 antigen, beta polypeptide 1 (p37); CD8 antigen, beta-chain; CD8 beta; CD8 beta chain; CD8 beta-2; CD8a; CD8A antigen alpha; CD8a molecule; CD8A; T-cell surface glycoprotein; CD8alpha; CD8B; CD8b antigen; CD8b molecule; CD8b molecule pseudogene; Cd8b1; CD8beta; CD8BP; fCD8; LEU2; Leu-2; Leu2 T-lymphocyte antigen; leu-2a; Ly-2; LY3; Ly-3; Ly-35; Ly-B; Ly-C; Lymphocyte antigen 3; Lyt2; Lyt-2; Lyt-2.1 lymphocyte differentiation antigen (AA at 100); Lyt3; Lyt-3; MAL; membrane glycoprotein; membrane protein; OKT8 T-cell antigen; OX-8 membrane antigen; p32; P37; RHACD8-4; T cell co-receptor; T lymphocyte surface glycoprotein beta chain; T8 T-cell antigen; T-cell antigen Leu2; T-cell membrane glycoprotein Ly-3; T-cell surface glycoprotein; T-cell surface glycoprotein CD8 alpha chain; T-cell surface glycoprotein CD8 beta chain; T-cell surface glycoprotein Lyt-2; T-cell surface glycoprotein Lyt-3; T-cell surface molecule; T-lymphocyte differentiation antigen T8/Leu-2; type I transmembrane glycoprotein

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
24930, 24931

Content And Storage:
4° C

Isotype:
IgG1

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FERMA549023

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Antigen:
CD96

Classification:
Monoclonal

Concentration:
100 μg/mL

Formulation:
PBS with 1% BSA and 0.02% sodium azide

Gene Accession No.:
Q3U0X8

Gene Symbols:
Cd96

Immunogen:
The monoclonal antibody 6A6 recognizes mouse CD96. CD96 or T cell-Activated

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Liquid

Applications:
Flow Cytometry, Functional Assay, Inhibition Assays, Western Blot

Clone:
6A6

Conjugate:
FITC

Gene:
Cd96

Gene Alias:
1700109I12Rik; Cd96; CD96 antigen; CD96 molecule; cell surface antigen CD96; DKFZp667E2122; sCD96; soluble CD96; T cell activation, increased late expression; t cell-activated increased late expression protein; Tactile; T-cell surface protein tactile

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
84544

Content And Storage:
4° C, store in dark

Isotype:
IgG2a

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Antigen:
VE-cadherin

Classification:
Monoclonal

Concentration:
100 μg/mL

Formulation:
PBS with 1% BSA and 0.02% sodium azide

Gene Accession No.:
P33151

Gene Symbols:
CDH5

Immunogen:
The monoclonal antibody BV9 binds to the extracellular domain (EC3-EC4) of human VE-cadherin (vascular endothelial cadherin)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry, Functional Assay, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Inhibition Assays, Western Blot

Clone:
BV9

Conjugate:
FITC

Gene:
CDH5

Gene Alias:
7B4; 7B4 antigen; 7B4/cadherin-5; AA408225; cadherin 5; cadherin 5, type 2 (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular epithelium); cadherin-5; cadherin-5; cd144 antigen; VE cadherin; Cd144; cd144 antigen; CDH5; cell-cell adhesion protein; endothelial-specific cadherin; vascular endothelial cadherin; vascular endothelial cadherin precursor; Vec; VEcad; VE-Cad; VE-cadherin; VECD

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
1003

Content And Storage:
4° C, store in dark

Isotype:
IgG2a