CD8 Monoclonal Antibody (15-11C5), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FERMA549022-Each-of-1 | In Stock | ₹ 38,416.44 |
FERMA549022 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,416.44
GST (18%): ₹ 6,914.959
Total Price: ₹ 45,331.399
Antigen
CD8
Classification
Monoclonal
Concentration
100 μg/mL
Formulation
PBS with 50% glycerol and 0.01% sodium azide
Gene Accession No.
P05541, P07725
Gene Symbols
Cd8a, CD8B
Immunogen
15-11C5 is derived from hybridization of mouse SP2/0 myeloma cells with spleen cells from Balb/c mice immunized with WAG/Rij spleen cells.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Rat
Form
Liquid
Applications
Flow Cytometry, Immunohistochemistry (Frozen)
Clone
15-11C5
Conjugate
Unconjugated
Gene
CD8B
Gene Alias
BB154331; CD8; CD8 alpha; CD8 alpha chain; CD8 alpha chain precursor; CD8 antigen; CD8 antigen 32 kDa chain; CD8 antigen 37 kDa chain; CD8 antigen alpha polypeptide; CD8 antigen alpha protein; CD8 antigen alpha protein precursor; CD8 antigen alpha-chain; CD8 antigen beta polypeptide; CD8 antigen beta polypeptide precursor; CD8 antigen beta-chain; CD8 antigen, alpha chain; CD8 antigen, alpha polypeptide; CD8 antigen, alpha polypeptide (p32); CD8 antigen, alpha-chain; CD8 antigen, beta chain; CD8 antigen, beta chain 1; CD8 antigen, beta polypeptide; CD8 antigen, beta polypeptide 1 (p37); CD8 antigen, beta-chain; CD8 beta; CD8 beta chain; CD8 beta-2; CD8a; CD8A antigen alpha; CD8a molecule; CD8A; T-cell surface glycoprotein; CD8alpha; CD8B; CD8b antigen; CD8b molecule; CD8b molecule pseudogene; Cd8b1; CD8beta; CD8BP; fCD8; LEU2; Leu-2; Leu2 T-lymphocyte antigen; leu-2a; Ly-2; LY3; Ly-3; Ly-35; Ly-B; Ly-C; Lymphocyte antigen 3; Lyt2; Lyt-2; Lyt-2.1 lymphocyte differentiation antigen (AA at 100); Lyt3; Lyt-3; MAL; membrane glycoprotein; membrane protein; OKT8 T-cell antigen; OX-8 membrane antigen; p32; P37; RHACD8-4; T cell co-receptor; T lymphocyte surface glycoprotein beta chain; T8 T-cell antigen; T-cell antigen Leu2; T-cell membrane glycoprotein Ly-3; T-cell surface glycoprotein; T-cell surface glycoprotein CD8 alpha chain; T-cell surface glycoprotein CD8 beta chain; T-cell surface glycoprotein Lyt-2; T-cell surface glycoprotein Lyt-3; T-cell surface molecule; T-lymphocyte differentiation antigen T8/Leu-2; type I transmembrane glycoprotein
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
24930, 24931
Content And Storage
4° C
Isotype
IgG1
Related Products
Description
- The monoclonal antibody recognizes rat CD8 antigen (MW 34 kDa and 39 kDa) and is reactive with all common inbred strains
- 15-11C5 is derived from hybridization of mouse SP2/0 myeloma cells with spleen cells from Balb/c mice immunized with WAG/Rij spleen cells
- Cluster of differentiation 8 (CD8), a type I transmembrane glycoprotein of the immunoglobulin family of receptors, plays an integral role in signal transduction, and T cell differentiation and activation
- CD8 is predominantly expressed on T cells as a disulfide-linked heterodimer of CD8alpha and CD8beta, where it functions as a co-receptor, along with T cell receptor (TCR), for major histocompatibilty complex class I (MHC-I) molecules; whereas its counterpart, CD4, acts as a co-receptor for MHC-II molecules
- CD8 exists on the cell surface, where the CD8alpha chain is essential for binding to MHC-I
- CD8 is also expressed on a subset of T cells, NK cells, monocytes and dendritic cells as disulfide-linked homodimers of CD8alpha
- Ligation of MHC-I/peptide complexes presented by antigen-presenting cells (APCs), triggers the recruitment of lymphocyte-specific protein tyrosine kinase (Lck), which leads to lymphokine production, motility and cytotoxic T lymphocyte (CTL) activation
- Once activated, CTLs play a crucial role in the clearance of pathogens and tumor cells
- Differentiation of naive CD8+ T cells into CTLs is strongly enhanced by IL-2, IL-12 and TGF-beta1.
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Antigen: CD8
Classification: Monoclonal
Concentration: 100 μg/mL
Formulation: PBS with 50% glycerol and 0.01% sodium azide
Gene Accession No.: P05541, P07725
Gene Symbols: Cd8a, CD8B
Immunogen: 15-11C5 is derived from hybridization of mouse SP2/0 myeloma cells with spleen cells from Balb/c mice immunized with WAG/Rij spleen cells.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Rat
Form: Liquid
Applications: Flow Cytometry, Immunohistochemistry (Frozen)
Clone: 15-11C5
Conjugate: Unconjugated
Gene: CD8B
Gene Alias: BB154331; CD8; CD8 alpha; CD8 alpha chain; CD8 alpha chain precursor; CD8 antigen; CD8 antigen 32 kDa chain; CD8 antigen 37 kDa chain; CD8 antigen alpha polypeptide; CD8 antigen alpha protein; CD8 antigen alpha protein precursor; CD8 antigen alpha-chain; CD8 antigen beta polypeptide; CD8 antigen beta polypeptide precursor; CD8 antigen beta-chain; CD8 antigen, alpha chain; CD8 antigen, alpha polypeptide; CD8 antigen, alpha polypeptide (p32); CD8 antigen, alpha-chain; CD8 antigen, beta chain; CD8 antigen, beta chain 1; CD8 antigen, beta polypeptide; CD8 antigen, beta polypeptide 1 (p37); CD8 antigen, beta-chain; CD8 beta; CD8 beta chain; CD8 beta-2; CD8a; CD8A antigen alpha; CD8a molecule; CD8A; T-cell surface glycoprotein; CD8alpha; CD8B; CD8b antigen; CD8b molecule; CD8b molecule pseudogene; Cd8b1; CD8beta; CD8BP; fCD8; LEU2; Leu-2; Leu2 T-lymphocyte antigen; leu-2a; Ly-2; LY3; Ly-3; Ly-35; Ly-B; Ly-C; Lymphocyte antigen 3; Lyt2; Lyt-2; Lyt-2.1 lymphocyte differentiation antigen (AA at 100); Lyt3; Lyt-3; MAL; membrane glycoprotein; membrane protein; OKT8 T-cell antigen; OX-8 membrane antigen; p32; P37; RHACD8-4; T cell co-receptor; T lymphocyte surface glycoprotein beta chain; T8 T-cell antigen; T-cell antigen Leu2; T-cell membrane glycoprotein Ly-3; T-cell surface glycoprotein; T-cell surface glycoprotein CD8 alpha chain; T-cell surface glycoprotein CD8 beta chain; T-cell surface glycoprotein Lyt-2; T-cell surface glycoprotein Lyt-3; T-cell surface molecule; T-lymphocyte differentiation antigen T8/Leu-2; type I transmembrane glycoprotein
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 24930, 24931
Content And Storage: 4° C
Isotype: IgG1
Antigen: CD96
Classification: Monoclonal
Concentration: 100 μg/mL
Formulation: PBS with 1% BSA and 0.02% sodium azide
Gene Accession No.: Q3U0X8
Gene Symbols: Cd96
Immunogen: The monoclonal antibody 6A6 recognizes mouse CD96. CD96 or T cell-Activated
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Form: Liquid
Applications: Flow Cytometry, Functional Assay, Inhibition Assays, Western Blot
Clone: 6A6
Conjugate: FITC
Gene: Cd96
Gene Alias: 1700109I12Rik; Cd96; CD96 antigen; CD96 molecule; cell surface antigen CD96; DKFZp667E2122; sCD96; soluble CD96; T cell activation, increased late expression; t cell-activated increased late expression protein; Tactile; T-cell surface protein tactile
Host Species: Rat
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 84544
Content And Storage: 4° C, store in dark
Isotype: IgG2a
Antigen: VE-cadherin
Classification: Monoclonal
Concentration: 100 μg/mL
Formulation: PBS with 1% BSA and 0.02% sodium azide
Gene Accession No.: P33151
Gene Symbols: CDH5
Immunogen: The monoclonal antibody BV9 binds to the extracellular domain (EC3-EC4) of human VE-cadherin (vascular endothelial cadherin)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Flow Cytometry, Functional Assay, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Inhibition Assays, Western Blot
Clone: BV9
Conjugate: FITC
Gene: CDH5
Gene Alias: 7B4; 7B4 antigen; 7B4/cadherin-5; AA408225; cadherin 5; cadherin 5, type 2 (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular epithelium); cadherin-5; cadherin-5; cd144 antigen; VE cadherin; Cd144; cd144 antigen; CDH5; cell-cell adhesion protein; endothelial-specific cadherin; vascular endothelial cadherin; vascular endothelial cadherin precursor; Vec; VEcad; VE-Cad; VE-cadherin; VECD
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 1003
Content And Storage: 4° C, store in dark
Isotype: IgG2a