FERMA549082
CD73 Monoclonal Antibody (4G4), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FERMA549082-Each-of-1 | In Stock | ₹ 54,073.92 |
FERMA549082 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 54,073.92
GST (18%): ₹ 9,733.306
Total Price: ₹ 63,807.226
Antigen
CD73
Classification
Monoclonal
Concentration
100 μg/mL
Formulation
PBS with 0.1% BSA and no preservative
Gene Accession No.
P21589
Gene Symbols
NT5E
Immunogen
Inflamed synovial stroma from rheumatoid arthritis patients
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
Flow Cytometry, Functional Assay, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Clone
4G4
Conjugate
Unconjugated
Gene
NT5E
Gene Alias
2210401F01Rik; 5 nucleotidase, ecto; 5' nucleotidase, ecto; 5'-NT; 5'-nucleotidase; 5'-nucleotidase ecto; 5'-nucleotidase, ecto (CD73); AI447961; CALJA; CD73; E5NT; ecto-5'-nucleotidase; eN; eNT; NT; Nt5; Nt5e; NTE; Purine 5-Prime-Nucleotidase
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
4907
Content And Storage
4° C
Isotype
IgG1
Related Products
Description
- The monoclonal antibody 4G4 recognizes both membrane bound and soluble human CD73, also known as ecto-5-nucleotidase
- The monoclonal antibody 4G4 causes a reduction in CD73 expression on lymphocytes, reduces enzyme activity, and inhibits the binding of lymphocytes to endothelial cells
- CD73 (Ecto-5-prime-nucleotidase, 5-prime-ribonucleotide phosphohydrolase) catalyzes the conversion at neutral pH of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP
- CD73 consists of a dimer of 2 identical 70 kDa subunits bound externally to the plasma membrane by a glycosyl phosphatidyl inositol linkage
- CD73 is used as a marker of lymphocyte differentiation
- Consequently, a deficiency of CD73 occurs in a variety of immunodeficiency diseases
- Other forms of 5-prime nucleotidase exist in the cytoplasm and lysosomes and can be distinguished from CD73 by their substrate affinities, requirement for divalent magnesium ion, activation by ATP, and inhibition by inorganic phosphate
- The CD73 gene has been localized to 6q14-q21 by immunofluorescence and a study of a panel of human x mouse hybrids that contained fragments of chromosome 6 as translocations
- Defects in the CD73 gene can lead to the calcification of joints and arteries, and intestinal tuberculosis
- Two transcript variants encoding different isoforms of CD73 have been found.
Compare Similar Items
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Antigen: CD73
Classification: Monoclonal
Concentration: 100 μg/mL
Formulation: PBS with 0.1% BSA and no preservative
Gene Accession No.: P21589
Gene Symbols: NT5E
Immunogen: Inflamed synovial stroma from rheumatoid arthritis patients
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Flow Cytometry, Functional Assay, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Clone: 4G4
Conjugate: Unconjugated
Gene: NT5E
Gene Alias: 2210401F01Rik; 5 nucleotidase, ecto; 5' nucleotidase, ecto; 5'-NT; 5'-nucleotidase; 5'-nucleotidase ecto; 5'-nucleotidase, ecto (CD73); AI447961; CALJA; CD73; E5NT; ecto-5'-nucleotidase; eN; eNT; NT; Nt5; Nt5e; NTE; Purine 5-Prime-Nucleotidase
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 4907
Content And Storage: 4° C
Isotype: IgG1
Antigen:
CD73
Classification:
Monoclonal
Concentration:
100 μg/mL
Formulation:
PBS with 0.1% BSA and no preservative
Gene Accession No.:
P21589
Gene Symbols:
NT5E
Immunogen:
Inflamed synovial stroma from rheumatoid arthritis patients
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Flow Cytometry, Functional Assay, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Clone:
4G4
Conjugate:
Unconjugated
Gene:
NT5E
Gene Alias:
2210401F01Rik; 5 nucleotidase, ecto; 5' nucleotidase, ecto; 5'-NT; 5'-nucleotidase; 5'-nucleotidase ecto; 5'-nucleotidase, ecto (CD73); AI447961; CALJA; CD73; E5NT; ecto-5'-nucleotidase; eN; eNT; NT; Nt5; Nt5e; NTE; Purine 5-Prime-Nucleotidase
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
4907
Content And Storage:
4° C
Isotype:
IgG1
Antigen: LOX-1
Classification: Monoclonal
Concentration: 100 μg/mL
Formulation: PBS with 0.1% BSA and no preservative
Gene Accession No.: P78380
Gene Symbols: OLR1
Immunogen: Fusion protein of extracellular domain (aa 71-273) of human LOX-1 with murine Fc-gamma1 (LOX-1-muFc) produced in PEAK cells
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Flow Cytometry, Functional Assay, Immunocytochemistry
Clone: 23C11
Conjugate: Unconjugated
Gene: OLR1
Gene Alias: CLEC8A; C-type lectin domain family 8 member A; hLOX 1; hLOX1; hLOX-1; lectin-like oxidized LDL receptor; lectin-like oxidized LDL receptor 1; lectin-like oxidized low-density lipoprotein receptor; Lectin-like oxidized low-density lipoprotein receptor-1; lectin-like oxLDL receptor 1; lectin-type oxidized LDL receptor 1; LOX 1; LOX1; LOX-1; LOXIN; Oldlr1; Oldr1; OLR1; ox LDL receptor 1; oxidised low density lipoprotein (lectin-like) receptor 1; oxidized low density lipoprotein (lectin-like) receptor 1; oxidized low density lipoprotein receptor 1; oxidized low-density lipoprotein receptor 1; Oxidized low-density lipoprotein receptor 1, soluble form; ox-LDL receptor 1; Scare1; scavenger receptor class E, member 1; sLOX 1; SLOX1; soluble LOX 1; SR-EI
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 4973
Content And Storage: 4° C
Isotype: IgG1
Antigen:
LOX-1
Classification:
Monoclonal
Concentration:
100 μg/mL
Formulation:
PBS with 0.1% BSA and no preservative
Gene Accession No.:
P78380
Gene Symbols:
OLR1
Immunogen:
Fusion protein of extracellular domain (aa 71-273) of human LOX-1 with murine Fc-gamma1 (LOX-1-muFc) produced in PEAK cells
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Flow Cytometry, Functional Assay, Immunocytochemistry
Clone:
23C11
Conjugate:
Unconjugated
Gene:
OLR1
Gene Alias:
CLEC8A; C-type lectin domain family 8 member A; hLOX 1; hLOX1; hLOX-1; lectin-like oxidized LDL receptor; lectin-like oxidized LDL receptor 1; lectin-like oxidized low-density lipoprotein receptor; Lectin-like oxidized low-density lipoprotein receptor-1; lectin-like oxLDL receptor 1; lectin-type oxidized LDL receptor 1; LOX 1; LOX1; LOX-1; LOXIN; Oldlr1; Oldr1; OLR1; ox LDL receptor 1; oxidised low density lipoprotein (lectin-like) receptor 1; oxidized low density lipoprotein (lectin-like) receptor 1; oxidized low density lipoprotein receptor 1; oxidized low-density lipoprotein receptor 1; Oxidized low-density lipoprotein receptor 1, soluble form; ox-LDL receptor 1; Scare1; scavenger receptor class E, member 1; sLOX 1; SLOX1; soluble LOX 1; SR-EI
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
4973
Content And Storage:
4° C
Isotype:
IgG1
Antigen: LOX-1
Classification: Monoclonal
Concentration: 100 μg/mL
Formulation: PBS with 0.1% BSA and 0.02% sodium azide
Gene Accession No.: P78380
Gene Symbols: OLR1
Immunogen: Fusion protein of extracellular domain (aa 71-273) of human LOX-1 with murine Fc-gamma1 (LOX-1-muFc) produced in PEAK cells
Quantity: 50 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Flow Cytometry, Functional Assay, Immunocytochemistry, Immunohistochemistry (Paraffin)
Clone: 23C11
Conjugate: Biotin
Gene: OLR1
Gene Alias: CLEC8A; C-type lectin domain family 8 member A; hLOX 1; hLOX1; hLOX-1; lectin-like oxidized LDL receptor; lectin-like oxidized LDL receptor 1; lectin-like oxidized low-density lipoprotein receptor; Lectin-like oxidized low-density lipoprotein receptor-1; lectin-like oxLDL receptor 1; lectin-type oxidized LDL receptor 1; LOX 1; LOX1; LOX-1; LOXIN; Oldlr1; Oldr1; OLR1; ox LDL receptor 1; oxidised low density lipoprotein (lectin-like) receptor 1; oxidized low density lipoprotein (lectin-like) receptor 1; oxidized low density lipoprotein receptor 1; oxidized low-density lipoprotein receptor 1; Oxidized low-density lipoprotein receptor 1, soluble form; ox-LDL receptor 1; Scare1; scavenger receptor class E, member 1; sLOX 1; SLOX1; soluble LOX 1; SR-EI
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 4973
Content And Storage: 4° C
Isotype: IgG1
Antigen:
LOX-1
Classification:
Monoclonal
Concentration:
100 μg/mL
Formulation:
PBS with 0.1% BSA and 0.02% sodium azide
Gene Accession No.:
P78380
Gene Symbols:
OLR1
Immunogen:
Fusion protein of extracellular domain (aa 71-273) of human LOX-1 with murine Fc-gamma1 (LOX-1-muFc) produced in PEAK cells
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Flow Cytometry, Functional Assay, Immunocytochemistry, Immunohistochemistry (Paraffin)
Clone:
23C11
Conjugate:
Biotin
Gene:
OLR1
Gene Alias:
CLEC8A; C-type lectin domain family 8 member A; hLOX 1; hLOX1; hLOX-1; lectin-like oxidized LDL receptor; lectin-like oxidized LDL receptor 1; lectin-like oxidized low-density lipoprotein receptor; Lectin-like oxidized low-density lipoprotein receptor-1; lectin-like oxLDL receptor 1; lectin-type oxidized LDL receptor 1; LOX 1; LOX1; LOX-1; LOXIN; Oldlr1; Oldr1; OLR1; ox LDL receptor 1; oxidised low density lipoprotein (lectin-like) receptor 1; oxidized low density lipoprotein (lectin-like) receptor 1; oxidized low density lipoprotein receptor 1; oxidized low-density lipoprotein receptor 1; Oxidized low-density lipoprotein receptor 1, soluble form; ox-LDL receptor 1; Scare1; scavenger receptor class E, member 1; sLOX 1; SLOX1; soluble LOX 1; SR-EI
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
4973
Content And Storage:
4° C
Isotype:
IgG1
Antigen: LOX-1
Classification: Monoclonal
Concentration: 100 μg/mL
Formulation: PBS with 1% BSA and 0.02% sodium azide
Gene Accession No.: P78380
Gene Symbols: OLR1
Immunogen: Fusion protein of extracellular domain (aa 71-273) of human LOX-1 with murine Fc-gamma1 (LOX-1-muFc) produced in PEAK cells
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Flow Cytometry, Functional Assay, Immunocytochemistry, Immunohistochemistry (Paraffin)
Clone: 23C11
Conjugate: FITC
Gene: OLR1
Gene Alias: CLEC8A; C-type lectin domain family 8 member A; hLOX 1; hLOX1; hLOX-1; lectin-like oxidized LDL receptor; lectin-like oxidized LDL receptor 1; lectin-like oxidized low-density lipoprotein receptor; Lectin-like oxidized low-density lipoprotein receptor-1; lectin-like oxLDL receptor 1; lectin-type oxidized LDL receptor 1; LOX 1; LOX1; LOX-1; LOXIN; Oldlr1; Oldr1; OLR1; ox LDL receptor 1; oxidised low density lipoprotein (lectin-like) receptor 1; oxidized low density lipoprotein (lectin-like) receptor 1; oxidized low density lipoprotein receptor 1; oxidized low-density lipoprotein receptor 1; Oxidized low-density lipoprotein receptor 1, soluble form; ox-LDL receptor 1; Scare1; scavenger receptor class E, member 1; sLOX 1; SLOX1; soluble LOX 1; SR-EI
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 4973
Content And Storage: 4° C, store in dark
Isotype: IgG1
Antigen:
LOX-1
Classification:
Monoclonal
Concentration:
100 μg/mL
Formulation:
PBS with 1% BSA and 0.02% sodium azide
Gene Accession No.:
P78380
Gene Symbols:
OLR1
Immunogen:
Fusion protein of extracellular domain (aa 71-273) of human LOX-1 with murine Fc-gamma1 (LOX-1-muFc) produced in PEAK cells
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Flow Cytometry, Functional Assay, Immunocytochemistry, Immunohistochemistry (Paraffin)
Clone:
23C11
Conjugate:
FITC
Gene:
OLR1
Gene Alias:
CLEC8A; C-type lectin domain family 8 member A; hLOX 1; hLOX1; hLOX-1; lectin-like oxidized LDL receptor; lectin-like oxidized LDL receptor 1; lectin-like oxidized low-density lipoprotein receptor; Lectin-like oxidized low-density lipoprotein receptor-1; lectin-like oxLDL receptor 1; lectin-type oxidized LDL receptor 1; LOX 1; LOX1; LOX-1; LOXIN; Oldlr1; Oldr1; OLR1; ox LDL receptor 1; oxidised low density lipoprotein (lectin-like) receptor 1; oxidized low density lipoprotein (lectin-like) receptor 1; oxidized low density lipoprotein receptor 1; oxidized low-density lipoprotein receptor 1; Oxidized low-density lipoprotein receptor 1, soluble form; ox-LDL receptor 1; Scare1; scavenger receptor class E, member 1; sLOX 1; SLOX1; soluble LOX 1; SR-EI
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
4973
Content And Storage:
4° C, store in dark
Isotype:
IgG1