FERMA549089

PrP Monoclonal Antibody (1.5D7), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FERMA549089-Each-of-1 In Stock ₹ 56,127.36

FERMA549089 - Each of 1

₹ 56,127.36

In Stock

Quantity

1

Base Price: ₹ 56,127.36

GST (18%): ₹ 10,102.925

Total Price: ₹ 66,230.285

Antigen

PrP

Classification

Monoclonal

Concentration

100 μg/mL

Formulation

PBS with 0.1% BSA and 0.02% sodium azide

Gene Accession No.

P10279

Gene Symbols

PRNP

Immunogen

The monoclonal antibody 1.5D7 recognizes the disease associated isoform of the prion protein termed PrPSc

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Bovine

Form

Liquid

Applications

Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Inhibition Assays, Western Blot

Clone

1.5D7

Conjugate

Unconjugated

Gene

PRNP

Gene Alias

AA960666; AI325101; Alternative prion protein; alternative prion protein; major prion protein; AltPrP; ASCR; BSE; CD230; CD230 antigen; CJD; GSS; KURU; major prion protein; major prion protein; alternative prion protein; major scrapie-associated fibril protein 1; MGC26679; p27-30; PK resistant core; prion protein; prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia); prion protein precursor; prion protein precursor PrP; prion protein PrP; prion protein variant a; prion protein variant b; prion protein, PrP; prion protein, structural; prion-related protein; PRIP; Prn; Prn-i; Prnp; Prn-p; PrP; PrP<C>; PrP27-30; PrP33-35C; PrPc; PrPSc; Sinc; SIP; TSE

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

281427

Content And Storage

4° C

Isotype

IgG2b

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Description

  • Human prion protein (PrP), also known as PRNP, is a ubiquitously expressed GPI-anchored cell surface glycoprotein associating with lipid raft components and functioning as a signaling molecule
  • PrP plays a role in apoptosis in a cell context-dependent manner, is involved in proliferation of epithelial cells and in distribution of junction-associated proteins in human enterocytes
  • Conversion of this normal cellular prion protein (PrPc) into an abnormal conformer (PrPSc) is the crucial step associated with triggering the pathogenesis of the prion neurodegenerative disorders, such as the Creutzfeld-Jakob disease (CJD)
  • Whereas PrPc is rich in alpha-helices, the PrPSc form has higher content of beta-sheets and is resistant to proteinase K.

Compare Similar Items

Show Difference

Img

Thermo Scientific

FERMA549089

--


Antigen:
PrP

Classification:
Monoclonal

Concentration:
100 μg/mL

Formulation:
PBS with 0.1% BSA and 0.02% sodium azide

Gene Accession No.:
P10279

Gene Symbols:
PRNP

Immunogen:
The monoclonal antibody 1.5D7 recognizes the disease associated isoform of the prion protein termed PrPSc

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Bovine

Form:
Liquid

Applications:
Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Inhibition Assays, Western Blot

Clone:
1.5D7

Conjugate:
Unconjugated

Gene:
PRNP

Gene Alias:
AA960666; AI325101; Alternative prion protein; alternative prion protein; major prion protein; AltPrP; ASCR; BSE; CD230; CD230 antigen; CJD; GSS; KURU; major prion protein; major prion protein; alternative prion protein; major scrapie-associated fibril protein 1; MGC26679; p27-30; PK resistant core; prion protein; prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia); prion protein precursor; prion protein precursor PrP; prion protein PrP; prion protein variant a; prion protein variant b; prion protein, PrP; prion protein, structural; prion-related protein; PRIP; Prn; Prn-i; Prnp; Prn-p; PrP; PrP<C>; PrP27-30; PrP33-35C; PrPc; PrPSc; Sinc; SIP; TSE

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
281427

Content And Storage:
4° C

Isotype:
IgG2b

Img

Thermo Scientific

FERMA549090

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Antigen:
EPCR

Classification:
Monoclonal

Concentration:
100 μg/mL

Formulation:
PBS with 1% BSA and 0.02% sodium azide

Gene Accession No.:
Q9UNN8

Gene Symbols:
Procr

Immunogen:
Human EPCR-positive RE-1 cells

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry, Functional Assay, Immunoprecipitation, Western Blot

Clone:
RCR-252

Conjugate:
FITC

Gene:
Procr

Gene Alias:
Activated protein C receptor; AI325044; APC receptor; bA42O4.2; CCCA; CCD41; CD antigen CD201; CD201; CD201 antigen; cell cycle, centrosome-associated protein; centrocyclin; Centrosomal protein CCD41; endothelial cell protein C receptor; Endothelial protein C receptor; Epcr; PROCR; protein C receptor; protein C receptor, endothelial

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
10544

Content And Storage:
4° C, store in dark

Isotype:
IgG1

Img

Thermo Scientific

FERMA549091

--


Antigen:
EPCR

Classification:
Monoclonal

Concentration:
100 μg/mL

Formulation:
PBS with 0.1% BSA and no preservative

Gene Accession No.:
Q9UNN8

Gene Symbols:
Procr

Immunogen:
The monoclonal antibody RCR-379 recognizes human endothelial protein C receptor (EPCR), a highly glycosylated type I transmembrane protein of 221-amino-acids.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen)

Clone:
RCR-379

Conjugate:
Unconjugated

Gene:
Procr

Gene Alias:
Activated protein C receptor; AI325044; APC receptor; bA42O4.2; CCCA; CCD41; CD antigen CD201; CD201; CD201 antigen; cell cycle, centrosome-associated protein; centrocyclin; Centrosomal protein CCD41; endothelial cell protein C receptor; Endothelial protein C receptor; Epcr; PROCR; protein C receptor; protein C receptor, endothelial

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
10544

Content And Storage:
4° C

Isotype:
IgG2a

Img

Thermo Scientific

FERMA549092

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Antigen:
Protein S

Classification:
Monoclonal

Concentration:
100 μg/mL

Formulation:
PBS with 1% BSA and 0.02% sodium azide

Gene Accession No.:
P07225

Gene Symbols:
PROS1

Immunogen:
Protein S

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry, Western Blot

Clone:
PS7

Conjugate:
FITC

Gene:
PROS1

Gene Alias:
AW214361; Preproprotein S; PROS; PROS 1; PROS1; protein S; protein S (alpha); Protein S alpha; protein Sa; proteinS; PS 21; PS 22; PS 23; PS 24; PS 25; PS 26; PS21; PS22; PS23; PS24; PS25; PS26; PSA; rabbit protein S; THPH5; THPH6; unnamed protein product; vitamin K-dependent plasma protein S; vitamin K-dependent protein S; vitamin K-dependent protein S precursor

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
5627

Content And Storage:
4° C, store in dark

Isotype:
IgG2a