FERMA549120

TNF alpha Monoclonal Antibody (T1), FITC, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FERMA549120-Each-of-1 In Stock ₹ 52,362.72

FERMA549120 - Each of 1

₹ 52,362.72

In Stock

Quantity

1

Base Price: ₹ 52,362.72

GST (18%): ₹ 9,425.29

Total Price: ₹ 61,788.01

Antigen

TNF alpha

Classification

Monoclonal

Concentration

100 μg/mL

Formulation

PBS with 1% BSA and 0.02% sodium azide

Gene Accession No.

P01375

Gene Symbols

Tnf

Immunogen

BALB/c mice with huTNF, fusion of spleen cells with NSO myeloma cells

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Flow Cytometry, Functional Assay, Inhibition Assays, Western Blot

Clone

T1

Conjugate

FITC

Gene

Tnf

Gene Alias

APC1 protein; Cachectin; C-domain 1; C-domain 2; cTNF; DADB-70P7.1; DIF; ICD1; ICD2; Intracellular domain 1; Intracellular domain 2; N-terminal fragment; NTF; RATTNF; Tnf; TNF alpha; TNF superfamily; TNF a; TNF, macrophage-derived; TNF, monocyte-derived; TNFA; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; TNFSF2; TNFa; TNLG1F; Tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor alpha (cachetin); tumor necrosis factor alpha precursor; tumor necrosis factor ligand 1F; tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form; tumor necrosis factor-alpha; tumor necrosis factor-alpha precursor; tumor-necrosis factor; tumour necrosis factor

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

7124

Content And Storage

4° C, store in dark

Isotype

IgG1

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Description

  • The antibody reacts with free soluble (17 kDa) and membrane (26 kDa) human TNF-alpha
  • The antibody inhibits the biological activity of both forms
  • It does not react with receptor bound TNF-alpha
  • TNF alpha is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily
  • This cytokine is mainly secreted by macrophage and bind to its receptors, TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR
  • TNF alpha is involved in the regulation of immune cells, cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation
  • TNF alpha exists as a multimer of two, three, or five noncovalently linked units, but shows a single 17 kDa band following SDS-PAGE under non-reducing conditions
  • Knockout studies in mice also suggested the neuroprotective function of TNF alpha, and has been observed to causes tumor necrosis when injected into tumor-bearing mice
  • Other functions of TNF-alpha include its role in the immune response to bacterial, viral, parasitic and certain fungal infections, as well as its role in the necrosis of specific tumors
  • TNF alpha causes cytolysis or cytostasis of certain transformed cells, being synergistic with interferon-gamma in its cytotoxicity
  • This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer.

Compare Similar Items

Show Difference

Img

Thermo Scientific

FERMA549120

--


Antigen:
TNF alpha

Classification:
Monoclonal

Concentration:
100 μg/mL

Formulation:
PBS with 1% BSA and 0.02% sodium azide

Gene Accession No.:
P01375

Gene Symbols:
Tnf

Immunogen:
BALB/c mice with huTNF, fusion of spleen cells with NSO myeloma cells

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry, Functional Assay, Inhibition Assays, Western Blot

Clone:
T1

Conjugate:
FITC

Gene:
Tnf

Gene Alias:
APC1 protein; Cachectin; C-domain 1; C-domain 2; cTNF; DADB-70P7.1; DIF; ICD1; ICD2; Intracellular domain 1; Intracellular domain 2; N-terminal fragment; NTF; RATTNF; Tnf; TNF alpha; TNF superfamily; TNF a; TNF, macrophage-derived; TNF, monocyte-derived; TNFA; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; TNFSF2; TNFa; TNLG1F; Tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor alpha (cachetin); tumor necrosis factor alpha precursor; tumor necrosis factor ligand 1F; tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form; tumor necrosis factor-alpha; tumor necrosis factor-alpha precursor; tumor-necrosis factor; tumour necrosis factor

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
7124

Content And Storage:
4° C, store in dark

Isotype:
IgG1

Img

Thermo Scientific

FERMA549121

--


Antigen:
TNFR1

Classification:
Monoclonal

Concentration:
100 μg/mL

Formulation:
PBS with 1% BSA and 0.02% sodium azide

Gene Accession No.:
P25118

Gene Symbols:
Tnfrsf1a

Immunogen:
Purified soluble extracellular domain of mouse TNF-RI.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Liquid

Applications:
Flow Cytometry, Functional Assay, Immunoprecipitation, Inhibition Assays

Clone:
55R-170

Conjugate:
FITC

Gene:
Tnfrsf1a

Gene Alias:
CD120a; CD120a antigen; FPF; hypothetical protein; metalloproteinase inhibitor 4; MGC19588; MS5; n-smase activation assoc. factor; p55; p55 TNF receptor; p55-R; p60; p62; p63; sCD120a; soluble CD120a; soluble TNFR1; sTNF RI; sTNFR I; sTNFR1; sTNFRI; TBP1; TBPI; TIMP metallopeptidase inhibitor 4; Timp4; TIMP-4; tissue inhibitor of metalloproteinase 4; tissue inhibitor of metalloproteinases 4; TNF receptor alpha chain; TNF receptor superfamily member 1A; TNF-alphaR1; TNF-alpha-R1; TNFalpha-R1; TNFAR; TNFR; TNF-R; TNFR I; TNFR1; TNF-R1; Tnfr-1; TNFR1-d2; Tnfr-2; TNFR55; TNF-R55; TNFR60; TNFRI; TNF-RI; TNF-R-I; TNFR-I; TNFRp55; Tnfrsf1a; tumor necrosis factor binding protein 1; Tumor necrosis factor receptor; tumor necrosis factor receptor 1; tumor necrosis factor receptor 1A isoform beta; tumor necrosis factor receptor superfamily member 1A; Tumor necrosis factor receptor superfamily member 1A, membrane form; tumor necrosis factor receptor superfamily, member 1A; tumor necrosis factor receptor type 1; tumor necrosis factor receptor type I; tumor necrosis factor-alpha receptor; Tumor necrosis factor-binding protein 1

Host Species:
Armenian Hamster

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
21937

Content And Storage:
4° C, store in dark

Isotype:
IgG

Img

Thermo Scientific

FERMA549122

--


Antigen:
TNFR1

Classification:
Monoclonal

Concentration:
100 μg/mL

Formulation:
PBS with 0.1% BSA and 0.02% sodium azide

Gene Accession No.:
P19438

Gene Symbols:
Tnfrsf1a

Immunogen:
Affinity-purified receptor material from HL60 cells containing ∽9 μg actively binding receptor

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry, Functional Assay, Immunoprecipitation, Inhibition Assays, Western Blot

Clone:
H398

Conjugate:
Biotin

Gene:
Tnfrsf1a

Gene Alias:
CD120a; CD120a antigen; FPF; hypothetical protein; metalloproteinase inhibitor 4; MGC19588; MS5; n-smase activation assoc. factor; p55; p55 TNF receptor; p55-R; p60; p62; p63; sCD120a; soluble CD120a; soluble TNFR1; sTNF RI; sTNFR I; sTNFR1; sTNFRI; TBP1; TBPI; TIMP metallopeptidase inhibitor 4; Timp4; TIMP-4; tissue inhibitor of metalloproteinase 4; tissue inhibitor of metalloproteinases 4; TNF receptor alpha chain; TNF receptor superfamily member 1A; TNF-alphaR1; TNF-alpha-R1; TNFalpha-R1; TNFAR; TNFR; TNF-R; TNFR I; TNFR1; TNF-R1; Tnfr-1; TNFR1-d2; Tnfr-2; TNFR55; TNF-R55; TNFR60; TNFRI; TNF-RI; TNF-R-I; TNFR-I; TNFRp55; Tnfrsf1a; tumor necrosis factor binding protein 1; Tumor necrosis factor receptor; tumor necrosis factor receptor 1; tumor necrosis factor receptor 1A isoform beta; tumor necrosis factor receptor superfamily member 1A; Tumor necrosis factor receptor superfamily member 1A, membrane form; tumor necrosis factor receptor superfamily, member 1A; tumor necrosis factor receptor type 1; tumor necrosis factor receptor type I; tumor necrosis factor-alpha receptor; Tumor necrosis factor-binding protein 1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
7132

Content And Storage:
4° C

Isotype:
IgG2a

Img

Thermo Scientific

FERMA549123

--


Antigen:
TNFR1

Classification:
Monoclonal

Concentration:
100 μg/mL

Formulation:
PBS with 1% BSA and 0.02% sodium azide

Gene Accession No.:
P19438

Gene Symbols:
Tnfrsf1a

Immunogen:
Affinity-purified receptor material from HL60 cells containing ∽9 μg actively binding receptor

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Immunoprecipitation, Inhibition Assays

Clone:
H398

Conjugate:
FITC

Gene:
Tnfrsf1a

Gene Alias:
CD120a; CD120a antigen; FPF; hypothetical protein; metalloproteinase inhibitor 4; MGC19588; MS5; n-smase activation assoc. factor; p55; p55 TNF receptor; p55-R; p60; p62; p63; sCD120a; soluble CD120a; soluble TNFR1; sTNF RI; sTNFR I; sTNFR1; sTNFRI; TBP1; TBPI; TIMP metallopeptidase inhibitor 4; Timp4; TIMP-4; tissue inhibitor of metalloproteinase 4; tissue inhibitor of metalloproteinases 4; TNF receptor alpha chain; TNF receptor superfamily member 1A; TNF-alphaR1; TNF-alpha-R1; TNFalpha-R1; TNFAR; TNFR; TNF-R; TNFR I; TNFR1; TNF-R1; Tnfr-1; TNFR1-d2; Tnfr-2; TNFR55; TNF-R55; TNFR60; TNFRI; TNF-RI; TNF-R-I; TNFR-I; TNFRp55; Tnfrsf1a; tumor necrosis factor binding protein 1; Tumor necrosis factor receptor; tumor necrosis factor receptor 1; tumor necrosis factor receptor 1A isoform beta; tumor necrosis factor receptor superfamily member 1A; Tumor necrosis factor receptor superfamily member 1A, membrane form; tumor necrosis factor receptor superfamily, member 1A; tumor necrosis factor receptor type 1; tumor necrosis factor receptor type I; tumor necrosis factor-alpha receptor; Tumor necrosis factor-binding protein 1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
7132

Content And Storage:
4° C, store in dark

Isotype:
IgG2a