MA122744

TNF alpha Monoclonal Antibody (2C8), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MA122744-Each-of-1 In Stock ₹ 48,555.30

MA122744 - Each of 1

₹ 48,555.30

In Stock

Quantity

1

Base Price: ₹ 48,555.30

GST (18%): ₹ 8,739.954

Total Price: ₹ 57,295.254

Antigen

TNF alpha

Classification

Monoclonal

Concentration

5.7 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.

P01375

Gene Symbols

Tnf

Immunogen

Human recombinant tumor necrosis factor of alpha type

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

ELISA, Immunohistochemistry, Inhibition Assays

Clone

2C8

Conjugate

Unconjugated

Gene

Tnf

Gene Alias

APC1 protein; Cachectin; C-domain 1; C-domain 2; cTNF; DADB-70P7.1; DIF; ICD1; ICD2; Intracellular domain 1; Intracellular domain 2; N-terminal fragment; NTF; RATTNF; Tnf; TNF alpha; TNF superfamily; TNF a; TNF, macrophage-derived; TNF, monocyte-derived; TNFA; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; TNFSF2; TNFa; TNLG1F; Tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor alpha (cachetin); tumor necrosis factor alpha precursor; tumor necrosis factor ligand 1F; tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form; tumor necrosis factor-alpha; tumor necrosis factor-alpha precursor; tumor-necrosis factor; tumour necrosis factor

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

7124

Content And Storage

4° C, do not freeze

Form

Liquid

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Description

  • MA1-22744 detects TNF alpha in Human samples
  • TNF alpha is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily
  • This cytokine is mainly secreted by macrophage and bind to its receptors, TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR
  • TNF alpha is involved in the regulation of immune cells, cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation
  • TNF alpha exists as a multimer of two, three, or five noncovalently linked units, but shows a single 17 kDa band following SDS-PAGE under non-reducing conditions
  • Knockout studies in mice also suggested the neuroprotective function of TNF alpha, and has been observed to causes tumor necrosis when injected into tumor-bearing mice
  • Other functions of TNF-alpha include its role in the immune response to bacterial, viral, parasitic and certain fungal infections, as well as its role in the necrosis of specific tumors
  • TNF alpha causes cytolysis or cytostasis of certain transformed cells, being synergistic with interferon-gamma in its cytotoxicity
  • This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer.

Compare Similar Items

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Thermo Scientific

MA122744

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Antigen:
TNF alpha

Classification:
Monoclonal

Concentration:
5.7 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.:
P01375

Gene Symbols:
Tnf

Immunogen:
Human recombinant tumor necrosis factor of alpha type

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Immunohistochemistry, Inhibition Assays

Clone:
2C8

Conjugate:
Unconjugated

Gene:
Tnf

Gene Alias:
APC1 protein; Cachectin; C-domain 1; C-domain 2; cTNF; DADB-70P7.1; DIF; ICD1; ICD2; Intracellular domain 1; Intracellular domain 2; N-terminal fragment; NTF; RATTNF; Tnf; TNF alpha; TNF superfamily; TNF a; TNF, macrophage-derived; TNF, monocyte-derived; TNFA; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; TNFSF2; TNFa; TNLG1F; Tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor alpha (cachetin); tumor necrosis factor alpha precursor; tumor necrosis factor ligand 1F; tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form; tumor necrosis factor-alpha; tumor necrosis factor-alpha precursor; tumor-necrosis factor; tumour necrosis factor

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
7124

Content And Storage:
4° C, do not freeze

Form:
Liquid

Img

Thermo Scientific

MA122819

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Antigen:
ErbB3

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
10mM PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P21860

Gene Symbols:
ERBB3

Immunogen:
Synthetic peptide corresponding to the cytoplasmic domain of human c-erbB-3 oncoprotein.

Quantity:
250 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgM

Applications:
Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Clone:
RTJ1

Conjugate:
Unconjugated

Gene:
ERBB3

Gene Alias:
avian erythroblastosis oncogene B 3; avian erythroblastosis oncogene B 3 receptor; C76256; c-erbB3; c-erbB-3; C-errB-3; erb-b2 receptor tyrosine kinase 3; ERBB3; Erbb-3; Erbb3r; erbB3-S; glial growth factor receptor; HER3; human epidermal growth factor receptor 3; LCCS2; MDA BF 1; MDA-BF-1; MGC88033; nuc-ErbB3; p180 ErbB3; p180-ErbB3; p45 sErbB3; p45-sErbB3; p85 sErbB3; p85-sErbB3; proto-oncogene-like protein c-ErbB-3; receptor tyrosine kinase; receptor tyrosine-protein kinase erbB-3; receptor tyrosine-protein kinase erbB-3; LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-3; tyrosine kinase-type cell surface receptor HER3; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)

Host Species:
Mouse

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
2065

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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MA123052

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Antigen:
S100

Classification:
Monoclonal

Concentration:
5.4 mg/mL

Formulation:
PBS with 0.1% sodium azide; pH 7.4

Gene Accession No.:
P04271, P23297

Gene Symbols:
S100A1, S100B

Immunogen:
Purified S100 protein from human brain.

Quantity:
500 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Affinity Purification, ELISA, Western Blot

Clone:
6G1

Conjugate:
Unconjugated

Gene:
S100A1

Gene Alias:
AI266795; AI850290; Bpb; hypothetical protein LOC525716; NEF; Protein S100-A1; protein S100-B; S 100; S100; S100 alpha; S100 calcium binding protein A1; S100 calcium binding protein B; S100 calcium-binding protein A1; S100 calcium-binding protein B; S100 calcium-binding protein beta (neural); S100 calcium-binding protein, beta (neural); S-100 calcium-binding protein, beta chain; S-100 protein alpha chain; S-100 protein beta chain; S-100 protein subunit alpha; S-100 protein subunit beta; S100 protein, alpha polypeptide; S100 protein, beta polypeptide; S100 protein, beta polypeptide, neural; S100a; S100A1; S100alpha; S100-alpha; S100B; S100-B; S100beta; S100P

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
6271, 6285

Content And Storage:
4° C, do not freeze

Form:
Liquid

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MA123056

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Antigen:
Epo

Classification:
Monoclonal

Concentration:
3.7 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.:
P01588

Gene Symbols:
EPO

Immunogen:
Recombinant full length protein (Human).

Quantity:
500 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA

Clone:
Epo2

Conjugate:
Unconjugated

Gene:
EPO

Gene Alias:
EP; EPO; Epoetin; erythropoietin; MGC138142; MVCD2

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
2056

Content And Storage:
4° C, do not freeze

Form:
Liquid