MA122819

ErbB3 Monoclonal Antibody (RTJ1), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MA122819-Each-of-1 In Stock ₹ 47,956.38

MA122819 - Each of 1

₹ 47,956.38

In Stock

Quantity

1

Base Price: ₹ 47,956.38

GST (18%): ₹ 8,632.148

Total Price: ₹ 56,588.528

Antigen

ErbB3

Classification

Monoclonal

Concentration

0.1 mg/mL

Formulation

10mM PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.

P21860

Gene Symbols

ERBB3

Immunogen

Synthetic peptide corresponding to the cytoplasmic domain of human c-erbB-3 oncoprotein.

Quantity

250 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgM

Applications

Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Clone

RTJ1

Conjugate

Unconjugated

Gene

ERBB3

Gene Alias

avian erythroblastosis oncogene B 3; avian erythroblastosis oncogene B 3 receptor; C76256; c-erbB3; c-erbB-3; C-errB-3; erb-b2 receptor tyrosine kinase 3; ERBB3; Erbb-3; Erbb3r; erbB3-S; glial growth factor receptor; HER3; human epidermal growth factor receptor 3; LCCS2; MDA BF 1; MDA-BF-1; MGC88033; nuc-ErbB3; p180 ErbB3; p180-ErbB3; p45 sErbB3; p45-sErbB3; p85 sErbB3; p85-sErbB3; proto-oncogene-like protein c-ErbB-3; receptor tyrosine kinase; receptor tyrosine-protein kinase erbB-3; receptor tyrosine-protein kinase erbB-3; LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-3; tyrosine kinase-type cell surface receptor HER3; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)

Host Species

Mouse

Purification Method

purified

Regulatory Status

RUO

Gene ID (Entrez)

2065

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Related Products

Img

Thermo Scientific

MA1-861

--

Img

Thermo Scientific

MA124678

--

Img

Thermo Scientific

OPA110100

--

Img

Thermo Scientific

PA1-1110

--

Img

Thermo Scientific

MA139544

--

Img

Thermo Scientific

MA126256

--

Img

Thermo Scientific

MA14674

--

Img

Thermo Scientific

PA130315

--

Description

  • Formalin-fixed paraffin-embedded tissues require antigen retrieval prior to immunostaining
  • ErbB3 (c-erbB-3/HER-3) is a member of the type I family of growth factor receptors and binds to ligands in the heregulin family
  • ErbB3 is over-expressed in a variety of tumors in the prostate, bladder, breast, stomach, pancreas, and colon
  • Heregulin and EGF stimulate tyrosine phosphorylation of c-erbB-3 to different extents
  • The ErbB3 gene is located on the long arm of human chromosome 12 (12q13) and is transcribed into a 6
  • 2kb mRNA which is translated into a 160/180 kDa glycoprotein
  • The ErbB3 gene encodes a transmembrane receptor tyrosine kinase due to alternative splicing and forms heterodimers with other EGF receptor family members that have kinase activity
  • Heterodimerization leads to the activation of pathways that lead to cell proliferation or differentiation
  • Alternate transcriptional splice variants encoding different isoforms of ErbB3 have been characterized
  • One ErbB3 isoform lacks the intermembrane region, is secreted outside the cell, and acts to modulate the activity of the membrane-bound form
  • Additional splice variants have also been reported, but they have not been thoroughly characterized.

Compare Similar Items

Show Difference

Img

Thermo Scientific

MA122819

--


Antigen:
ErbB3

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
10mM PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P21860

Gene Symbols:
ERBB3

Immunogen:
Synthetic peptide corresponding to the cytoplasmic domain of human c-erbB-3 oncoprotein.

Quantity:
250 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgM

Applications:
Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Clone:
RTJ1

Conjugate:
Unconjugated

Gene:
ERBB3

Gene Alias:
avian erythroblastosis oncogene B 3; avian erythroblastosis oncogene B 3 receptor; C76256; c-erbB3; c-erbB-3; C-errB-3; erb-b2 receptor tyrosine kinase 3; ERBB3; Erbb-3; Erbb3r; erbB3-S; glial growth factor receptor; HER3; human epidermal growth factor receptor 3; LCCS2; MDA BF 1; MDA-BF-1; MGC88033; nuc-ErbB3; p180 ErbB3; p180-ErbB3; p45 sErbB3; p45-sErbB3; p85 sErbB3; p85-sErbB3; proto-oncogene-like protein c-ErbB-3; receptor tyrosine kinase; receptor tyrosine-protein kinase erbB-3; receptor tyrosine-protein kinase erbB-3; LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-3; tyrosine kinase-type cell surface receptor HER3; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)

Host Species:
Mouse

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
2065

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

MA123052

--


Antigen:
S100

Classification:
Monoclonal

Concentration:
5.4 mg/mL

Formulation:
PBS with 0.1% sodium azide; pH 7.4

Gene Accession No.:
P04271, P23297

Gene Symbols:
S100A1, S100B

Immunogen:
Purified S100 protein from human brain.

Quantity:
500 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Affinity Purification, ELISA, Western Blot

Clone:
6G1

Conjugate:
Unconjugated

Gene:
S100A1

Gene Alias:
AI266795; AI850290; Bpb; hypothetical protein LOC525716; NEF; Protein S100-A1; protein S100-B; S 100; S100; S100 alpha; S100 calcium binding protein A1; S100 calcium binding protein B; S100 calcium-binding protein A1; S100 calcium-binding protein B; S100 calcium-binding protein beta (neural); S100 calcium-binding protein, beta (neural); S-100 calcium-binding protein, beta chain; S-100 protein alpha chain; S-100 protein beta chain; S-100 protein subunit alpha; S-100 protein subunit beta; S100 protein, alpha polypeptide; S100 protein, beta polypeptide; S100 protein, beta polypeptide, neural; S100a; S100A1; S100alpha; S100-alpha; S100B; S100-B; S100beta; S100P

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
6271, 6285

Content And Storage:
4° C, do not freeze

Form:
Liquid

Img

Thermo Scientific

MA123056

--


Antigen:
Epo

Classification:
Monoclonal

Concentration:
3.7 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.:
P01588

Gene Symbols:
EPO

Immunogen:
Recombinant full length protein (Human).

Quantity:
500 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA

Clone:
Epo2

Conjugate:
Unconjugated

Gene:
EPO

Gene Alias:
EP; EPO; Epoetin; erythropoietin; MGC138142; MVCD2

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
2056

Content And Storage:
4° C, do not freeze

Form:
Liquid

Img

Thermo Scientific

MA123152

--


Antigen:
ATM

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
Q13315, Q62388

Gene Symbols:
ATM

Immunogen:
Recombinant protein expressed in E. coli corresponding to amino acids 2577-3056.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
ChIP Assay, ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
2C1

Conjugate:
Unconjugated

Gene:
ATM

Gene Alias:
AI256621; AT mutated; A-T mutated; A-T mutated homolog; AT mutated protein; AT1; ATA; Ataxia t; Ataxia telangiectasia gene mutated in human beings; ataxia telangiectasia mutated; Ataxia telangiectasia mutated homolog; ATC; ATD; ATDC; ATE; Atm; ATM (phospho S1981); ATM (pS1981); ATM (pSer1981); ATM phospho S1981; ATM phospho Ser1981; ATM serine/threonine kinase; C030026E19Rik; DKFZp781A0353; EC 2.7.1.37; MGC74674; phospho ATM; phospho S1981 ATM; serine-protein kinase ATM; TEL1; TEL1, telomere maintenance 1, homolog; TELO1

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11920, 300711, 472

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid