MA1-861

ErbB4 Monoclonal Antibody (HFR1), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MA1-861-Each-of-1 In Stock ₹ 44,448.42

MA1-861 - Each of 1

₹ 44,448.42

In Stock

Quantity

1

Base Price: ₹ 44,448.42

GST (18%): ₹ 8,000.716

Total Price: ₹ 52,449.136

Antigen

ErbB4

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.

Q15303, Q61527

Gene Symbols

ERBB4

Immunogen

Synthetic Peptide: C R(1250) S T L Q H P D Y L Q E Y S T(1264)

Quantity

200 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG2b

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

HFR1

Conjugate

Unconjugated

Gene

ERBB4

Gene Alias

4ICD; ALS19; avian erythroblastic leukemia viral (v-erb-b2) oncogene homolog 4; avian erythroblastosis oncogene B 4; c-erbB-4; erb-b2 receptor tyrosine kinase 4; Erbb4; ERBB4 intracellular domain; ERBB4 transcript variant I12DEL; ERBB4 transcript variant I20DEL; Her4; human epidermal growth factor receptor 4; Mer4; OTTHUMP00000209432; p180erbB4; proto-oncogene-like protein c-ErbB-4; receptor tyrosine kinase; receptor tyrosine-protein kinase erbB-4; s80HER4; Tyro-2; Tyrosine kinase-type cell surface receptor HER4; v-erb-a erythroblastic leukemia viral oncogene homolog 4; v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian); v-erb-b2 avian erythroblastic leukemia viral oncogene 4; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

13869, 2066

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • MA1-861 detects Her-4 from human and mouse samples
  • MA1-861 has been successfully used in immunoprecipitation, immunohistochemical, and Western blotting procedures
  • By Western blot, this antibody detects ∽185 kDa protein representing Her-4 from human A431 cell and mouse NIH3T3/HER4 cell extracts.This antibody has also been used in immunohistochemical, using paraffin embedded mouse NIH3T3 cells
  • MA1-861 immunizing peptide corresponds to amino acid residues 1250 to 1264 of human Her-4 oncoprotein
  • Oncogene ERBB4 (HER4) is a member of the type I receptor protein tyrosine subfamily that includes EGFR, ERBB2, and ERBB3
  • ERBB4 binds and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation
  • ErbB 4 is activated by neuregulins and NTAK (neural and thymus derived activator for ErbB kinases)
  • ErbB 4 is a receptor for heregulin and is capable of mediating HGL-stimulated tyrosine phosphorylation of itself
  • Like other protein kinases, ErbB 4 mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation
  • ErbB 4 is most predominantly expressed in several breast carcinoma cell lines, and in normal skeletal muscle, heart, pituitary, brain, and cerebellum
  • Breast tumor cell lines T47-D, MDA-MB-453, BT-474 and H3396 are found to have the highest levels of mRNA, and intermediate levels are seen in MCF-7, MDAMB-330 and MDA-MB-361
  • Expression of ErbB 4 is low or absent in some breast tumor cell lines such as MDA-MB-231, MDA-MB-157, MDA-MB-468, and SKBR-3
  • ErbB 4 levels have been found to be elevated in certain human tumor cell lines suggesting that it may play a role in some malignancies.

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Thermo Scientific

MA1-861

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Antigen:
ErbB4

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
Q15303, Q61527

Gene Symbols:
ERBB4

Immunogen:
Synthetic Peptide: C R(1250) S T L Q H P D Y L Q E Y S T(1264)

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
HFR1

Conjugate:
Unconjugated

Gene:
ERBB4

Gene Alias:
4ICD; ALS19; avian erythroblastic leukemia viral (v-erb-b2) oncogene homolog 4; avian erythroblastosis oncogene B 4; c-erbB-4; erb-b2 receptor tyrosine kinase 4; Erbb4; ERBB4 intracellular domain; ERBB4 transcript variant I12DEL; ERBB4 transcript variant I20DEL; Her4; human epidermal growth factor receptor 4; Mer4; OTTHUMP00000209432; p180erbB4; proto-oncogene-like protein c-ErbB-4; receptor tyrosine kinase; receptor tyrosine-protein kinase erbB-4; s80HER4; Tyro-2; Tyrosine kinase-type cell surface receptor HER4; v-erb-a erythroblastic leukemia viral oncogene homolog 4; v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian); v-erb-b2 avian erythroblastic leukemia viral oncogene 4; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
13869, 2066

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

MA1-934

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Antigen:
Calcium Sensing Receptor

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
P35384, P41180, P48442, Q9QY96

Gene Symbols:
CASR

Immunogen:
Synthetic peptide corresponding to residues (214) A D D D Y G R P G I E K F RE E A E E R D I (235) of human calcium sensing receptor.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG2a

Applications:
ELISA, Immunohistochemistry (Frozen), Western Blot

Clone:
5C10, ADD, ADD

Conjugate:
Unconjugated

Gene:
CASR

Gene Alias:
BoPCaR1; Ca sensing receptor; Ca(2+)-sensing receptor; calcium sensing receptor; calcium-sensing receptor; Calcium-sensing receptor (hypocalciuric hypercalcemia 1 severe neonatal hyperparathyroidism); Calcium-sensing receptor (hypocalciuric hypercalcemia 1, severe neonatal hyperparathyroidism); CaR; CaSR; CaSR antibody; cation sensing receptor; EIG8; Extracellular calcium-sensing receptor; FHH; FIH; G protein coupled receptor, family C, group 2, member A; G protein-coupled receptor, family C, group 2, member A; Gprc2a; HHC; HHC1; HYPOC1; LOW QUALITY PROTEIN: extracellular calcium-sensing receptor; NSHPT; parathyroid Ca(2+)-sensing receptor 1; parathyroid cell calcium-sensing receptor; Parathyroid cell calcium-sensing receptor 1; PCaR1

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
12374, 24247, 281038, 846

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

MA1-950

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Antigen:
Bcl-3

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
P20749, Q9Z2F6

Gene Symbols:
Bcl3

Immunogen:
Full length mouse Bcl-3 protein.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Flow Cytometry, Western Blot

Clone:
Ham150-3.5

Conjugate:
Unconjugated

Gene:
Bcl3

Gene Alias:
AI528691; B cell leukemia/lymphoma 3; B-cell CLL/lymphoma 3; B-cell leukemia/lymphoma 3; B-cell lymphoma 3 protein; B-cell lymphoma 3 protein homolog; B-cell lymphoma 3-encoded protein; BCL3; BCL-3; Bcl-3 protein; BCL4; chronic lymphatic leukemia protein; D19S37; Proto-oncogene BCL3

Host Species:
Armenian Hamster

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
12051, 602

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

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Thermo Scientific

MA1014D550

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Antigen:
SOX2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with proprietary stabilizer and 0.02% sodium azide

Gene Accession No.:
P48431, P48432

Gene Symbols:
SOX2

Immunogen:
Full-length human recombinant protein expressed in bacteria

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunocytochemistry

Clone:
20G5

Conjugate:
DyLight 550

Gene:
SOX2

Gene Alias:
ANOP3; cb236; Delta EF2a; lcc; MCOPS3; MCOPS3 (Microphthalmia Syndromic type 3); RGD1565646; sex determining region Y-box 2; SOX 2; SOX2; Sox-2; soxp; SRY (sex determining region Y) box 2; SRY (sex determining region Y)-box 2; SRY box 2; SRY related HMG box 2; SRY-box 2; SRY-box 2; SOX2; SRY-box containing gene 2; SRY-box transcription factor 2; SRY-related HMG-box gene 2; transcription factor SOX2; transcription factor SOX-2; wu:fb83g04; wu:fc14d07; ysb; zgc:65860; zgc:77389

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
20674, 6657

Content And Storage:
4° C, do not freeze

Form:
Liquid