MA1216
THRB Monoclonal Antibody (J52), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MA1216-Each-of-1 | In Stock | ₹ 48,041.94 |
MA1216 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,041.94
GST (18%): ₹ 8,647.549
Total Price: ₹ 56,689.489
Antigen
THRB
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.4
Gene Accession No.
P10828, P18113, P37242
Gene Symbols
THRB
Immunogen
Purified human TR beta -1 protein.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG1
Applications
Gel Shift, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone
J52
Conjugate
Unconjugated
Gene
THRB
Gene Alias
c-erbA-2; c-erbAbeta; C-ERBA-BETA; ERBA 2; ERBA BETA; ERBA2; ERBA-BETA; fj24f03; GRTH; LOW QUALITY PROTEIN: thyroid hormone receptor beta; MGC126109; MGC126110; NR1A2; Nuclear receptor subfamily 1 group A member 2; oncogene ERBA2; PRTH; RATT3REC; si:ch211-264a6.2; T3R[b]; T3Rbeta; T3rec; THR; THR1; thr2; Thrb; Thrb1; Thrb2; thyroid hormone nuclear receptor beta variant 1; thyroid hormone receptor beta; thyroid hormone receptor beta 1; thyroid hormone receptor beta 2; thyroid hormone receptor beta 3; thyroid hormone receptor beta1; thyroid hormone receptor beta-1; thyroid hormone receptor beta2; thyroid hormone receptor beta2delta; thyroid hormone receptor, beta (avian erythroblastic leukemia viral (v-erb-a) oncogene homolog 2); thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian); TR; TR beta; TR beta 1; TR[b]1; trb; TR-B1C-ERBA-2; TRbeta; TR-beta; TRbeta1; TRbeta2Delta; wu:fj24f03
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
21834, 24831, 7068
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- MA1-216 detects thyroid hormone receptor (TR) beta-1 in human, mouse, rat, and transformed bacterial cells
- This antibody is specific for the TR beta-1 isoform
- MA1-216 has been successfully used in Western blot, immunocytochemistry, immunoprecipitation and gel shift procedures
- By Western blot, this antibody detects a 52 and a 55 kDa protein representing recombinant TR expressed in E
- coli
- The two different sizes represent two different translational starting points
- Immunocytochemical staining of TR beta-1 in intact GH3 cells with MA1-216 results in nuclear staining
- When levels of expression of the transfected receptor are high, cytoplasmic staining is seen along with nuclear staining
- Immunoprecipitation and gel super shift experiments show that MA1-216 reacts with the unliganded, liganded, and DNA binding forms of the receptor
- The MA1-216 immunogen is purified human TR beta-1 overexpressed in E
- coli
- This antibody recognizes an epitope in the A/B domain of human TR beta-1, amino acid residues 1-101
- Thyroid hormone receptors (TR), also known as c-erbA-2, are ligand-dependent, intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences called hormone response elements following activation by the appropriate hormone
- Thyroid hormones, through their interaction with TR, effect metabolic processes, growth and development in many tissues by regulating the expression of genes for growth hormone, malic enzyme and several hepatic proteins
- There are two forms of TR; TR alpha (on chromosome 17) and TR beta (on chromosome 3)
- Each of these isoforms also has two isoforms; TR alpha-1 and TRv alpha-2, and TR beta-1 and TR beta-2 respectively
- TR alpha-1 and 2 are identical through amino acid 370 where their sequences diverge
- TRv alpha-2, which does not bind T3 and is a strong negative regulator of the functional TR, is 80 amino acids longer than TR alpha-1
- The corresponding gene for the thyroid hormone receptor beta-1 is NR1A2.
Compare Similar Items
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Antigen: THRB
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.4
Gene Accession No.: P10828, P18113, P37242
Gene Symbols: THRB
Immunogen: Purified human TR beta -1 protein.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG1
Applications: Gel Shift, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: J52
Conjugate: Unconjugated
Gene: THRB
Gene Alias: c-erbA-2; c-erbAbeta; C-ERBA-BETA; ERBA 2; ERBA BETA; ERBA2; ERBA-BETA; fj24f03; GRTH; LOW QUALITY PROTEIN: thyroid hormone receptor beta; MGC126109; MGC126110; NR1A2; Nuclear receptor subfamily 1 group A member 2; oncogene ERBA2; PRTH; RATT3REC; si:ch211-264a6.2; T3R[b]; T3Rbeta; T3rec; THR; THR1; thr2; Thrb; Thrb1; Thrb2; thyroid hormone nuclear receptor beta variant 1; thyroid hormone receptor beta; thyroid hormone receptor beta 1; thyroid hormone receptor beta 2; thyroid hormone receptor beta 3; thyroid hormone receptor beta1; thyroid hormone receptor beta-1; thyroid hormone receptor beta2; thyroid hormone receptor beta2delta; thyroid hormone receptor, beta (avian erythroblastic leukemia viral (v-erb-a) oncogene homolog 2); thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian); TR; TR beta; TR beta 1; TR[b]1; trb; TR-B1C-ERBA-2; TRbeta; TR-beta; TRbeta1; TRbeta2Delta; wu:fj24f03
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 21834, 24831, 7068
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
THRB
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.4
Gene Accession No.:
P10828, P18113, P37242
Gene Symbols:
THRB
Immunogen:
Purified human TR beta -1 protein.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
Gel Shift, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
J52
Conjugate:
Unconjugated
Gene:
THRB
Gene Alias:
c-erbA-2; c-erbAbeta; C-ERBA-BETA; ERBA 2; ERBA BETA; ERBA2; ERBA-BETA; fj24f03; GRTH; LOW QUALITY PROTEIN: thyroid hormone receptor beta; MGC126109; MGC126110; NR1A2; Nuclear receptor subfamily 1 group A member 2; oncogene ERBA2; PRTH; RATT3REC; si:ch211-264a6.2; T3R[b]; T3Rbeta; T3rec; THR; THR1; thr2; Thrb; Thrb1; Thrb2; thyroid hormone nuclear receptor beta variant 1; thyroid hormone receptor beta; thyroid hormone receptor beta 1; thyroid hormone receptor beta 2; thyroid hormone receptor beta 3; thyroid hormone receptor beta1; thyroid hormone receptor beta-1; thyroid hormone receptor beta2; thyroid hormone receptor beta2delta; thyroid hormone receptor, beta (avian erythroblastic leukemia viral (v-erb-a) oncogene homolog 2); thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian); TR; TR beta; TR beta 1; TR[b]1; trb; TR-B1C-ERBA-2; TRbeta; TR-beta; TRbeta1; TRbeta2Delta; wu:fj24f03
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
21834, 24831, 7068
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: Hepatitis B Virus Core Antigen
Classification: Monoclonal
Concentration: 4.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.: __
Gene Symbols: __
Immunogen: Recombinant full length protein.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Virus
Product Type: Antibody
Isotype: IgG2a
Applications: ELISA, Western Blot
Clone: H6F5
Conjugate: Unconjugated
Gene: __
Gene Alias: ayw; HBc; HBcAg; HBV; HepB
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: 4° C, do not freeze
Form: Liquid
Antigen:
Hepatitis B Virus Core Antigen
Classification:
Monoclonal
Concentration:
4.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
Recombinant full length protein.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Virus
Product Type:
Antibody
Isotype:
IgG2a
Applications:
ELISA, Western Blot
Clone:
H6F5
Conjugate:
Unconjugated
Gene:
__
Gene Alias:
ayw; HBc; HBcAg; HBV; HepB
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
4° C, do not freeze
Form:
Liquid
Antigen: Fibrillarin
Classification: Monoclonal
Concentration: Conc. Not Determined
Formulation: tissue culture supernatant with 10mM sodium azide
Gene Accession No.: P22087, P22509, P35550, Q22053
Gene Symbols: fbl, fib-1
Immunogen: Yeast nuclear preparation (S cerevisiae)Hybridomas were screened by immunofluorescence on yeast cells and by western blotting on yeast protein homogenates (S cerevisiae)
Quantity: 250 μL
Primary or Secondary: Primary
Target Species: C. elegans, Drosophila, Human, Mouse, Plant, Rat, Yeast
Product Type: Antibody
Isotype: IgG1
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: 38F3
Conjugate: Unconjugated
Gene: fbl
Gene Alias: 34 kDa nucleolar scleroderma antigen; 34-kD nucleolar scleroderma antigen; AL022665; AT20009p; CELE_T01C3.7; CG5725; CG5725-PA; CG5725-PB; CG5725-PC; CG5725-PD; CG5725-PE; CG5725-PF; CG5725-PG; Dmel\CG5725; Dmel_CG5725; dPANK; dPANK/Fbl; Fbl; fbl-PA; fbl-PB; fbl-PC; fbl-PD; fbl-PE; fbl-PF; fbl-PG; FIB; FIB1; fib-1; fibrillarin; FLRN; fumble; histone-glutamine methyltransferase; LD24618p; LP11571p; nucleolar protein 1; PANK; pantothenate kinase; RNA, U3 small nucleolar interacting protein 1; RNU3IP1; rRNA 2'-O-methyltransferase fibrillarin; T01C3.7
Host Species: Mouse
Purification Method: __
Regulatory Status: RUO
Gene ID (Entrez): 14113, 179999, 2091, 292747, 46234
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Fibrillarin
Classification:
Monoclonal
Concentration:
Conc. Not Determined
Formulation:
tissue culture supernatant with 10mM sodium azide
Gene Accession No.:
P22087, P22509, P35550, Q22053
Gene Symbols:
fbl, fib-1
Immunogen:
Yeast nuclear preparation (S cerevisiae)Hybridomas were screened by immunofluorescence on yeast cells and by western blotting on yeast protein homogenates (S cerevisiae)
Quantity:
250 μL
Primary or Secondary:
Primary
Target Species:
C. elegans, Drosophila, Human, Mouse, Plant, Rat, Yeast
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
38F3
Conjugate:
Unconjugated
Gene:
fbl
Gene Alias:
34 kDa nucleolar scleroderma antigen; 34-kD nucleolar scleroderma antigen; AL022665; AT20009p; CELE_T01C3.7; CG5725; CG5725-PA; CG5725-PB; CG5725-PC; CG5725-PD; CG5725-PE; CG5725-PF; CG5725-PG; Dmel\CG5725; Dmel_CG5725; dPANK; dPANK/Fbl; Fbl; fbl-PA; fbl-PB; fbl-PC; fbl-PD; fbl-PE; fbl-PF; fbl-PG; FIB; FIB1; fib-1; fibrillarin; FLRN; fumble; histone-glutamine methyltransferase; LD24618p; LP11571p; nucleolar protein 1; PANK; pantothenate kinase; RNA, U3 small nucleolar interacting protein 1; RNU3IP1; rRNA 2'-O-methyltransferase fibrillarin; T01C3.7
Host Species:
Mouse
Purification Method:
__
Regulatory Status:
RUO
Gene ID (Entrez):
14113, 179999, 2091, 292747, 46234
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Desmin
Classification: Monoclonal
Concentration: 9.9 mg/mL
Formulation: Ascites with 15mM sodium azide
Gene Accession No.: O62654, P02540, P17661, P31001, P48675
Gene Symbols: DES
Immunogen: Purified, full length, native, pig desmin protein.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Bovine, Feline, Goat, Hamster, Human, Multi-species, Mouse, Ovine, Porcine, Rabbit, Rat
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: DE-U-10
Conjugate: Unconjugated
Gene: DES
Gene Alias: CMD1I; CSM1; CSM2; DES; Desmin; desmin-like protein; FLJ12025; FLJ39719; FLJ41013; FLJ41793; I79_018932; intermediate filament protein; LGMD2R; MFM1; muscle-specific intermediate filament desmin; muscle-specific intermediate filament protein; mutant desmin p.K241E; SCPNK; similar to desmin
Host Species: Mouse
Purification Method: __
Regulatory Status: RUO
Gene ID (Entrez): 100328890, 100764990, 101097010, 101117308, 102180712, 13346, 1674, 280765, 396725, 64362
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Desmin
Classification:
Monoclonal
Concentration:
9.9 mg/mL
Formulation:
Ascites with 15mM sodium azide
Gene Accession No.:
O62654, P02540, P17661, P31001, P48675
Gene Symbols:
DES
Immunogen:
Purified, full length, native, pig desmin protein.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Bovine, Feline, Goat, Hamster, Human, Multi-species, Mouse, Ovine, Porcine, Rabbit, Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
DE-U-10
Conjugate:
Unconjugated
Gene:
DES
Gene Alias:
CMD1I; CSM1; CSM2; DES; Desmin; desmin-like protein; FLJ12025; FLJ39719; FLJ41013; FLJ41793; I79_018932; intermediate filament protein; LGMD2R; MFM1; muscle-specific intermediate filament desmin; muscle-specific intermediate filament protein; mutant desmin p.K241E; SCPNK; similar to desmin
Host Species:
Mouse
Purification Method:
__
Regulatory Status:
RUO
Gene ID (Entrez):
100328890, 100764990, 101097010, 101117308, 102180712, 13346, 1674, 280765, 396725, 64362
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid