FERMA549362

Syk Recombinant Rabbit Monoclonal Antibody (PSH0-76), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 FERMA549362-Each-of-1 In Stock ₹ 38,074.20

FERMA549362 - Each of 1

₹ 38,074.20

In Stock

Quantity

1

Base Price: ₹ 38,074.20

GST (18%): ₹ 6,853.356

Total Price: ₹ 44,927.556

Antigen

Syk

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

P43405

Gene Symbols

Syk

Immunogen

Synthetic peptide within human aa 451-500 / 635.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Clone

PSH0-76

Conjugate

Unconjugated

Gene

Syk

Gene Alias

DKFZp313N1010, EC 2.7.10.2, FLJ25043, FLJ37489, HGNC:11205, kinase Syk, KSYK, p72Syk, p72-Syk, ptk72, SP1, spleen associated tyrosine kinase, spleen tyrosine kinase, SYK, syk signaling, Sykb, tyrosine-kinase syk, tyrosine-protein kinase SYK

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

6850

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG

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Description

  • Sequence Similarities: 100% Mouse
  • Tissue Specificity: Widely expressed in hematopoietic cells (at protein level) (PubMed:8163536)
  • Expressed in neutrophils (at protein level) (PubMed:15123770)
  • Within the B-cell compartment, expressed from pro- and pre-B cells to plasma cells (PubMed:8163536)
  • Positive Control: Raji cell lysate, Daudi cell lysate, SW620 cell lysate, Ramos cell lysate
  • Subcellular Location: Cell membrane, Cytoplasm, cytosol
  • Predicted band size: 72 kDa
  • Spleen tyrosine kinase (SYK), along with ZAP70, are cytoplasmic tyrosine kinases that are viewed as potential druge targets for allergic disorders and autoimmune diseases
  • SYK may also play a role in cancer
  • Syk translocates to the plasma membrane upon B cell antigen receptor (BCR) or the high-affinity IgE receptor (FcepsilonRI) triggering, and phosphorylates downstream adaptor proteins, thereby providing docking sites for initiation of subsequent signaling pathways, such as calcium mobilization, cytoskeleton remodeling, or transcription of specific genes
  • Syk binds to the receptor assemblies through interactions of its pair of SH2 domains with ITAM motives of the receptor, which have been phosphorylated by Src-family kinases
  • These kinases also help to activate Syk by phosphorylation of its activation loop.

Compare Similar Items

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Img

Thermo Scientific

FERMA549362

--


Antigen:
Syk

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P43405

Gene Symbols:
Syk

Immunogen:
Synthetic peptide within human aa 451-500 / 635.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Clone:
PSH0-76

Conjugate:
Unconjugated

Gene:
Syk

Gene Alias:
DKFZp313N1010, EC 2.7.10.2, FLJ25043, FLJ37489, HGNC:11205, kinase Syk, KSYK, p72Syk, p72-Syk, ptk72, SP1, spleen associated tyrosine kinase, spleen tyrosine kinase, SYK, syk signaling, Sykb, tyrosine-kinase syk, tyrosine-protein kinase SYK

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
6850

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG

Img

Thermo Scientific

FERMA549363

--


Antigen:
VISTA

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q9H7M9

Gene Symbols:
VSIR

Immunogen:
Recombinant protein within human vista aa 1-194 / 311.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
PSH0-64

Conjugate:
Unconjugated

Gene:
VSIR

Gene Alias:
4632428N05Rik, B7H5, B7-H5, C10orf54, C1H10orf54, C28H10orf54, C4H10orf54, chromosome 10 open reading frame 54, DD1alpha, Death Domain1alpha, Dies1, differentiation of ESCs 1, GI24, PD-1H, PDCD1 homolog, PD-H1, platelet receptor Gi24, PP2135, RIKEN cDNA 4632428N05 gene, SISP1, sisp-1, Stress-induced secreted protein-1, UNQ730/PRO1412, V-domain Ig suppressor of T cell activation, VISTA, V-set domain-containing immunoregulatory receptor, V-set immunoregulatory receptor, VSIR, V-type immunoglobulin domain-containing suppressor of T-cell activation

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
64115

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG

Img

Thermo Scientific

FERMA549607

--


Antigen:
RAB3A

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P20336, P63011, P63012

Gene Symbols:
RAB3A

Immunogen:
Synthetic peptide within human rab3a aa 121-170/220

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
PSH01-08

Conjugate:
Unconjugated

Gene:
RAB3A

Gene Alias:
C18A3.6; RAB3; Rab3a; RAB3A, member RAS oncogene family; RAS-associated protein RAB3A; ras-related protein Rab-3A; ras-related protein Rab-3A-like protein; Ras-related small GTP binding protein 3A

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
19339, 25531, 5864

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG

Img

Thermo Scientific

FERMA549608

--


Antigen:
HCLS1

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P14317

Gene Symbols:
HCLS1

Immunogen:
Recombinant protein within human hcls1 aa 201-450/486

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
PSH01-12

Conjugate:
Unconjugated

Gene:
HCLS1

Gene Alias:
AW213261; CTTNL; HCLS1; hematopoietic cell specific Lyn substrate 1; hematopoietic cell-specific Lyn substrate 1; Hematopoietic lineage cell-specific protein; HS1; LckBP1; p75

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3059

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG