FERMA549363

VISTA Recombinant Rabbit Monoclonal Antibody (PSH0-64), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FERMA549363-Each-of-1 In Stock ₹ 38,074.20

FERMA549363 - Each of 1

₹ 38,074.20

In Stock

Quantity

1

Base Price: ₹ 38,074.20

GST (18%): ₹ 6,853.356

Total Price: ₹ 44,927.556

Antigen

VISTA

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

Q9H7M9

Gene Symbols

VSIR

Immunogen

Recombinant protein within human vista aa 1-194 / 311.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

PSH0-64

Conjugate

Unconjugated

Gene

VSIR

Gene Alias

4632428N05Rik, B7H5, B7-H5, C10orf54, C1H10orf54, C28H10orf54, C4H10orf54, chromosome 10 open reading frame 54, DD1alpha, Death Domain1alpha, Dies1, differentiation of ESCs 1, GI24, PD-1H, PDCD1 homolog, PD-H1, platelet receptor Gi24, PP2135, RIKEN cDNA 4632428N05 gene, SISP1, sisp-1, Stress-induced secreted protein-1, UNQ730/PRO1412, V-domain Ig suppressor of T cell activation, VISTA, V-set domain-containing immunoregulatory receptor, V-set immunoregulatory receptor, VSIR, V-type immunoglobulin domain-containing suppressor of T-cell activation

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

64115

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG

Related Products

Img

Thermo Scientific

FERMA549607

--

Img

Thermo Scientific

FERMA549608

--

Img

Thermo Scientific

FERMA549360

--

Img

Thermo Scientific

MA191124

--

Img

Thermo Scientific

MA181870

--

Img

Thermo Scientific

FERMA549609

--

Img

Thermo Scientific

FERMA549610

--

Img

Thermo Scientific

MA123158

--

Description

  • Sequence Similarities: 95% Mouse/Rat
  • Tissue Specificity: Expressed in spleen
  • Detected on a number of myeloid cells including CD11b monocytes, CD66b-positive neutrophils, at low levels on CD4-positive and CD8-positive T-cells, and in a subset of NK cells
  • Not detected on B cells (at protein level)
  • Expressed at high levels in placenta, spleen, plasma blood leukocytes, and lung
  • Expressed at moderate levels in lymph node, bone marrow, fat, uterus, and trachea
  • Has low expression levels in other tissues
  • Positive Control: Human brain tissue, human placenta tissue, human tonsil tissue, A375 cell lysate, HeLa cell lysate, human lung tissue lysate
  • Subcellular Location: Cell membrane
  • Predicted band size: 34 kDa
  • VISTA (V-domain Ig containing suppressor of T-cell activation), also known as B7-H5 or PD-1H, is a product of the VSIR gene
  • Although VISTA bears sequence homology to PD-L1 it has a different expression pattern
  • In both mouse and humans, VISTA is expressed predominantly on hematopoietic cells with the highest densities on myeloid cells, and lower levels on T cells
  • It is usually absent on B cells
  • VISTA expressed by antigen presenting cells has been shown to directly suppress proliferation and cytokine production of CD4 and CD8 T cells, making it a target for cancer immunotherapy
  • The reported ligands of VISTA include CD28H, VSIG-3 and VSIG-8.

Compare Similar Items

Show Difference

Img

Thermo Scientific

FERMA549363

--


Antigen:
VISTA

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q9H7M9

Gene Symbols:
VSIR

Immunogen:
Recombinant protein within human vista aa 1-194 / 311.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
PSH0-64

Conjugate:
Unconjugated

Gene:
VSIR

Gene Alias:
4632428N05Rik, B7H5, B7-H5, C10orf54, C1H10orf54, C28H10orf54, C4H10orf54, chromosome 10 open reading frame 54, DD1alpha, Death Domain1alpha, Dies1, differentiation of ESCs 1, GI24, PD-1H, PDCD1 homolog, PD-H1, platelet receptor Gi24, PP2135, RIKEN cDNA 4632428N05 gene, SISP1, sisp-1, Stress-induced secreted protein-1, UNQ730/PRO1412, V-domain Ig suppressor of T cell activation, VISTA, V-set domain-containing immunoregulatory receptor, V-set immunoregulatory receptor, VSIR, V-type immunoglobulin domain-containing suppressor of T-cell activation

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
64115

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG

Img

Thermo Scientific

FERMA549607

--


Antigen:
RAB3A

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P20336, P63011, P63012

Gene Symbols:
RAB3A

Immunogen:
Synthetic peptide within human rab3a aa 121-170/220

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
PSH01-08

Conjugate:
Unconjugated

Gene:
RAB3A

Gene Alias:
C18A3.6; RAB3; Rab3a; RAB3A, member RAS oncogene family; RAS-associated protein RAB3A; ras-related protein Rab-3A; ras-related protein Rab-3A-like protein; Ras-related small GTP binding protein 3A

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
19339, 25531, 5864

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG

Img

Thermo Scientific

FERMA549608

--


Antigen:
HCLS1

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P14317

Gene Symbols:
HCLS1

Immunogen:
Recombinant protein within human hcls1 aa 201-450/486

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
PSH01-12

Conjugate:
Unconjugated

Gene:
HCLS1

Gene Alias:
AW213261; CTTNL; HCLS1; hematopoietic cell specific Lyn substrate 1; hematopoietic cell-specific Lyn substrate 1; Hematopoietic lineage cell-specific protein; HS1; LckBP1; p75

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3059

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG

Img

Thermo Scientific

FERMA549609

--


Antigen:
KEAP1

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P57790, Q14145, Q9Z2X8

Gene Symbols:
Keap1

Immunogen:
Recombinant protein within human keap1 aa 275-624/624

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Clone:
PSH0-90

Conjugate:
Unconjugated

Gene:
Keap1

Gene Alias:
cytosolic inhibitor of Nrf2; INrf2; Keap1; kelch like ECH associated protein 1; Kelch-like ECH-associated protein 1; kelch-like family member 19; kelch-like protein 19; Kiaa0132; KLHL19; mKIAA0132; NRF2 cytosolic inhibitor; ring canal protein

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
117519, 50868, 9817

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG