FERMA549360

GPNMB Recombinant Rabbit Monoclonal Antibody (PSH0-82), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FERMA549360-Each-of-1 In Stock ₹ 38,074.20

FERMA549360 - Each of 1

₹ 38,074.20

In Stock

Quantity

1

Base Price: ₹ 38,074.20

GST (18%): ₹ 6,853.356

Total Price: ₹ 44,927.556

Antigen

GPNMB

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

Q14956, Q6P7C7, Q99P91

Gene Symbols

GPNMB

Immunogen

Recombinant protein within human gpnmb aa 1-498 / 572.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Liquid

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

PSH0-82

Conjugate

Unconjugated

Gene

GPNMB

Gene Alias

Dchil, DC-HIL, dendritic cell-associated heparin sulfate proteoglycan-dependent integrin ligand, dendritic cell-associated transmembrane protein, glycoprotein (transmembrane) nmb, glycoprotein nmb, glycoprotein nmb-like protein, glycoprotein nonmetastatic melanoma protein B, Gpnmb, hematopoietic growth factor inducible neurokinin-1, Hematopoietic growth factor inducible neurokinin-1 type, Hgfin, ipd, iris pigment dispersion, NMB, Osteoactivin, si:ch211-155k24.6, transmembrane glycoprotein HGFIN, transmembrane glycoprotein NMB, Unknown (protein for MGC:133733), UNQ1725/PRO9925

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

10457, 113955, 93695

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG

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Description

  • Sequence Similarities: 98% Mouse/Rat
  • Tissue Specificity: Widely expressed, but very low expression, if any, in the brain (PubMed:12609765, PubMed:16609006)
  • Expressed in the epidermis with higher levels in melanocytes compared with keratinocytes and Langerhans cells (at protein level) (PubMed:29336782)
  • Expressed in peripheral blood, but not bone marrow mononuclear cells (PubMed:12609765)
  • Expressed in tissue macrophages, including liver Kuppfer cells and lung alveolar macrophages, in podocytes and in some cells of the ciliary body of the eye (at protein level) (PubMed:16489096)
  • May be overexpressed in various cancers, including melanoma and glioblastoma multiforme (PubMed:7814155, PubMed:16489096, PubMed:16609006)
  • Positive Control: L929 cell lysate, A375 cell lysate, U-937 cell lysate, rat heart tissue lysate, B16F1 cell lysates, human lung tissue, L929
  • Subcellular Location: Cell membrane, Melanosome membrane, Early endosome membrane
  • Predicted band size: 64 kDa
  • The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein
  • GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines
  • GPNMB may be involved in growth delay and reduction of metastatic potential
  • Two transcript variants encoding different isoforms have been found for this gene.

Compare Similar Items

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Img

Thermo Scientific

FERMA549360

--


Antigen:
GPNMB

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q14956, Q6P7C7, Q99P91

Gene Symbols:
GPNMB

Immunogen:
Recombinant protein within human gpnmb aa 1-498 / 572.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
PSH0-82

Conjugate:
Unconjugated

Gene:
GPNMB

Gene Alias:
Dchil, DC-HIL, dendritic cell-associated heparin sulfate proteoglycan-dependent integrin ligand, dendritic cell-associated transmembrane protein, glycoprotein (transmembrane) nmb, glycoprotein nmb, glycoprotein nmb-like protein, glycoprotein nonmetastatic melanoma protein B, Gpnmb, hematopoietic growth factor inducible neurokinin-1, Hematopoietic growth factor inducible neurokinin-1 type, Hgfin, ipd, iris pigment dispersion, NMB, Osteoactivin, si:ch211-155k24.6, transmembrane glycoprotein HGFIN, transmembrane glycoprotein NMB, Unknown (protein for MGC:133733), UNQ1725/PRO9925

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
10457, 113955, 93695

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG

Img

Thermo Scientific

FERMA549361

--


Antigen:
SIAH1

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P61092, Q06985, Q8IUQ4, Q920M9

Gene Symbols:
SIAH1, Siah1a, Siah1b

Immunogen:
Synthetic peptide within human siah1 aa 1-50 / 282.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
PSH0-46

Conjugate:
Unconjugated

Gene:
SIAH1

Gene Alias:
AA960570, AA982064, AI853500, E3 ubiquitin-protein ligase SIAH1, E3 ubiquitin-protein ligase SIAH1A, E3 ubiquitin-protein ligase SIAH1B, FLJ08065, h HUMSIAH, hSIAH1, HUMSIAH, mSiah-1a, RING-type E3 ubiquitin transferase SIAH1, RING-type E3 ubiquitin transferase SIAH1A, RING-type E3 ubiquitin transferase SIAH1B, seven in absentia 1A, seven in absentia 1B, seven in absentia homolog 1, Seven in absentia homolog 1a, Seven in absentia homolog 1b, SIAH, siah E3 ubiquitin protein ligase 1, SIAH1, siah-1, Siah1a, Siah-1a, Siah1b, siah-1b, Sinh1a, Sinh1b

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
110337437, 140941, 20437, 20438, 6477

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG

Img

Thermo Scientific

FERMA549362

--


Antigen:
Syk

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P43405

Gene Symbols:
Syk

Immunogen:
Synthetic peptide within human aa 451-500 / 635.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Clone:
PSH0-76

Conjugate:
Unconjugated

Gene:
Syk

Gene Alias:
DKFZp313N1010, EC 2.7.10.2, FLJ25043, FLJ37489, HGNC:11205, kinase Syk, KSYK, p72Syk, p72-Syk, ptk72, SP1, spleen associated tyrosine kinase, spleen tyrosine kinase, SYK, syk signaling, Sykb, tyrosine-kinase syk, tyrosine-protein kinase SYK

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
6850

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG

Img

Thermo Scientific

FERMA549363

--


Antigen:
VISTA

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q9H7M9

Gene Symbols:
VSIR

Immunogen:
Recombinant protein within human vista aa 1-194 / 311.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
PSH0-64

Conjugate:
Unconjugated

Gene:
VSIR

Gene Alias:
4632428N05Rik, B7H5, B7-H5, C10orf54, C1H10orf54, C28H10orf54, C4H10orf54, chromosome 10 open reading frame 54, DD1alpha, Death Domain1alpha, Dies1, differentiation of ESCs 1, GI24, PD-1H, PDCD1 homolog, PD-H1, platelet receptor Gi24, PP2135, RIKEN cDNA 4632428N05 gene, SISP1, sisp-1, Stress-induced secreted protein-1, UNQ730/PRO1412, V-domain Ig suppressor of T cell activation, VISTA, V-set domain-containing immunoregulatory receptor, V-set immunoregulatory receptor, VSIR, V-type immunoglobulin domain-containing suppressor of T-cell activation

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
64115

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG