MA182747

Podoplanin Monoclonal Antibody (4D5aE5E6), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MA182747-Each-of-1 In Stock ₹ 56,897.40

MA182747 - Each of 1

₹ 56,897.40

In Stock

Quantity

1

Base Price: ₹ 56,897.40

GST (18%): ₹ 10,241.532

Total Price: ₹ 67,138.932

Antigen

Podoplanin

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with <0.1% sodium azide

Gene Accession No.

Q86YL7

Gene Symbols

PDPN

Immunogen

ORF Human podoplanin ectodomain expressed in E.coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)

Clone

4D5aE5E6

Conjugate

Unconjugated

Gene

PDPN

Gene Alias

29kDa cytosolic podoplanin intracellular domain; Aggrus; CTA-520D8.1; E11; E11 antigen epitope; epithelial cell surface transmembrane protein antigen; glycoprotein 36; Glycoprotein 38; glycoprotein, 36-KD; GP36; Gp38; GP40; HT1A-1; hT1alpha-1; hT1alpha-2; lung type I cell membrane associated glycoprotein; lung type-I cell membrane-associated glycoprotein (T1A-2); Ots8; OTS-8; OTTHUMP00000009640; OTTHUMP00000044504; PA2.26; PA2.26 antigen; PDPN; PICD; Podoplanin; PSEC0003; PSEC0025; pulmonary type I alveolar epithelial cell transmembrane differentiation marker; RANDAM-2; RP23-348F1.2; RTI140; RTI40; T1a; T1A2; T1A-2; T1alpha; T1-alpha; TI1A; Transmembrane glycoprotein E11; type I cell 40 kDa protein

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

10630

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Heat-mediated antigen retrieval using a sodium citrate buffer (pH 6.0) is recommended for the staining of paraffin sections
  • A suggested positive control for immunohistochemical applications is normal lung
  • Mouse anti Human podoplanin antibody, clone 4D5aE5E6 recognizes human podoplanin also known as gp36, Aggrus, PA2.26 antigen or T1 alpha
  • Podoplanin (PDPN, T1A, gp38, Aggrus) is a mucin type-1 glycoprotein with a 40-43 kDa molecular weight
  • Podoplanin is expressed in many tumors and normal cells, especially lymphatic epithelial cells and follicular DCs
  • Podoplanin localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells
  • As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes
  • Podoplanin appears to serve as a ligand for CLEC-2 and expression is positively correlated with tumors expressing greater invasive and metastatic potential
  • Podoplanin is directly involved in cell migration, aids metastases formation and tumor cell invasion of tissue
  • Further, it has also been determined that podoplanin expression is induced through Src activation of Cas and, recently, there are indications of podoplanin presence on Th17 cells
  • Initial studies below indicate the presence of podoplanin on a small but distinct population of CD4+ cells from human PBMC
  • Dysfunction of the podoplanin protein has been linked to diseases such as lymphangioma and subglottis neoplasm
  • Podoplanin has also been proposed as a marker for lung injury due to the physiological function of the protein.

Compare Similar Items

Show Difference

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Thermo Scientific

MA182747

--


Antigen:
Podoplanin

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with <0.1% sodium azide

Gene Accession No.:
Q86YL7

Gene Symbols:
PDPN

Immunogen:
ORF Human podoplanin ectodomain expressed in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)

Clone:
4D5aE5E6

Conjugate:
Unconjugated

Gene:
PDPN

Gene Alias:
29kDa cytosolic podoplanin intracellular domain; Aggrus; CTA-520D8.1; E11; E11 antigen epitope; epithelial cell surface transmembrane protein antigen; glycoprotein 36; Glycoprotein 38; glycoprotein, 36-KD; GP36; Gp38; GP40; HT1A-1; hT1alpha-1; hT1alpha-2; lung type I cell membrane associated glycoprotein; lung type-I cell membrane-associated glycoprotein (T1A-2); Ots8; OTS-8; OTTHUMP00000009640; OTTHUMP00000044504; PA2.26; PA2.26 antigen; PDPN; PICD; Podoplanin; PSEC0003; PSEC0025; pulmonary type I alveolar epithelial cell transmembrane differentiation marker; RANDAM-2; RP23-348F1.2; RTI140; RTI40; T1a; T1A2; T1A-2; T1alpha; T1-alpha; TI1A; Transmembrane glycoprotein E11; type I cell 40 kDa protein

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
10630

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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MA182787

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Antigen:
Phosphotyrosine

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
BBS with <0.1% sodium azide; pH 8.0

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Proprietary Immunogen.

Quantity:
500 μg

Primary or Secondary:
Primary

Target Species:
Chemical

Product Type:
Antibody

Isotype:
IgG2b

Applications:
ELISA, Immunocytochemistry, Western Blot

Clone:
pY20

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
Phosphotyrosine; pTyr; pY

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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MA182801

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Antigen:
CD200R

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative; pH 7.4

Gene Accession No.:
Q9ES57

Gene Symbols:
CD200R1

Immunogen:
Fusion protein mCD200RCD4d3+4.

Quantity:
500 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Flow Cytometry

Clone:
OX-110

Conjugate:
Unconjugated

Gene:
CD200R1

Gene Alias:
antigen identified by monoclonal antibody MRC OX-2 receptor; CD200 cell surface glycoprotein receptor; CD200 R1; CD200 receptor 1; CD200R; Cd200r1; Cell surface glycoprotein CD200 receptor 1; cell surface glycoprotein OX2 receptor 1; cell surface glycoprotein receptor CD200; CRTR2; HCRTR2; MOX2 receptor; MOX2R; Orexin receptor 2; OX102 antigen; OX2 receptor; OX2R; UNQ2522/PRO6015

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
57781

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

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MA182814

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Antigen:
Complement C3b

Classification:
Monoclonal

Concentration:
1.05 mg/mL

Formulation:
BBS with <0.1% sodium azide

Gene Accession No.:
P01024

Gene Symbols:
C3

Immunogen:
Purified human iC3b.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Clone:
013III-1.16

Conjugate:
Unconjugated

Gene:
C3

Gene Alias:
Acylation stimulating protein; acylation-stimulating protein cleavage product; AHUS5; AI255234; ARMD9; ASP; C3; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; C3a; C3a anaphylatoxin; C3adesArg; C3b; C3bc; C3-beta-c; Complement C3; Complement C3 alpha chain; Complement C3 beta chain; Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3c alpha' chain fragment 2; Complement C3d fragment; Complement C3dg fragment; Complement C3f fragment; Complement C3g fragment; complement component 3; complement component C3a; complement component C3b; CPAMD1; ENCF-1; ENCF-2; epididymis secretory sperm binding protein Li 62p; HEL-S-62p; HSE-MSF; iC3b; Neutrophil chemotactic factor-1; Neutrophil chemotactic factor-2; Plp; prepro-C3

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
718

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid