MA12021

Acetylated Lysine Monoclonal Antibody (1C6), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MA12021-Each-of-1 In Stock ₹ 48,084.72

MA12021 - Each of 1

₹ 48,084.72

In Stock

Quantity

1

Base Price: ₹ 48,084.72

GST (18%): ₹ 8,655.25

Total Price: ₹ 56,739.97

Antigen

Acetylated Lysine

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1mg/mL BSA and 0.05% sodium azide

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Target Species

Chemical

Product Type

Antibody

Isotype

IgG2b

Applications

ChIP Assay, Dot Blot, Immunocytochemistry, Immunoprecipitation, Peptide Array, Western Blot

Clone

1C6

Conjugate

Unconjugated

Gene Alias

Acetyl Lysine; Acetylated Lysine; Acetyllysine

Immunogen

Synthetic peptide sequence surrounding the acetylated lysine 9 of histone H3.

Quantity

100 μg

Primary or Secondary

Primary

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Target Molecule

Chemical

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Description

  • MA1-2021 detects human and mouse, and monkey acetylated lysine
  • MA1-2021 has been used successfully in Western blot, immunoprecipitation, dot blot, ChIP Assay, and immunofluorescence (cells) procedures
  • By Western blot, this antibody may detect a ladder of acetylated proteins in HeLa cell lysate
  • In immunofluorescence procedures, MA1-2021 recognizes acetylated lysine in gamma irradiated HeLa cells
  • The MA1-2021 immunogen is a synthetic peptide sequence surrounding the acetylated lysine 9 of histone H3
  • In the nucleus, DNA is tightly packed into nucleosomes generating an environment which is highly repressive towards DNA processes such as transcription
  • Acetylation of lysine residues within proteins has emerged as an important mechanism used by cells to overcome this repression
  • The acetylation of non-histone proteins such as transcription factors, as well as histones appears to be involved in this process
  • Acetylation may result in structural transitions as well as specific signaling within discrete chromatin domains
  • The role of acetylation in intracellular signaling has been inferred from the binding of acetylated peptides by the conserved bromodomain
  • Furthermore, recent findings suggest that bromodomain/acetylated-lysine recognition can serve as a regulatory mechanism in protein-protein interactions in numerous cellular processes such as chromatin remodeling and transcriptional activation.

Compare Similar Items

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Img

Thermo Scientific

MA12021

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Antigen:
Acetylated Lysine

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Target Species:
Chemical

Product Type:
Antibody

Isotype:
IgG2b

Applications:
ChIP Assay, Dot Blot, Immunocytochemistry, Immunoprecipitation, Peptide Array, Western Blot

Clone:
1C6

Conjugate:
Unconjugated

Gene Alias:
Acetyl Lysine; Acetylated Lysine; Acetyllysine

Immunogen:
Synthetic peptide sequence surrounding the acetylated lysine 9 of histone H3.

Quantity:
100 μg

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Target Molecule:
Chemical

Img

Thermo Scientific

MA12022

--


Antigen:
Phospho-Histone H2A.X (Ser139)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
3F2

Conjugate:
Unconjugated

Gene Alias:
AW228881; gamma H2AX; gammaH2ax; H2A histone family member X; H2A histone family, member X; H2A.X; H2A.X variant histone; H2A/X; h2afx; H2ax; H2AX histone; Hist5-2ax; histone 5 protein 2ax; histone H2A.x; Histone H2a/x; Histone H2AX; RGD1566119; similar to H2A histone family, member X; zgc:56329

Immunogen:
Synthetic peptide sequence surrounding phosphorylated Ser140

Quantity:
100 μg

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Target Molecule:
__

Img

Thermo Scientific

MA12023

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Antigen:
TRIM28

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

Applications:
ChIP Assay, Gel Shift, Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
20C1

Conjugate:
Unconjugated

Gene Alias:
AA408787; E3 SUMO-protein ligase TRIM28; KAP1; KAP-1; KRAB [Kruppel-associated box domain]-associated protein 1; KRAB-A-interacting protein; KRAB-associated protein 1; KRAB-interacting p; KRAB-interacting protein 1; Krip1; KRIP-1; MommeD9; Nuclear corepressor KAP-1; PPP1R157; protein phosphatase 1, regulatory subunit 157; RING finger protein 96; RING-type E3 ubiquitin transferase TIF1-beta; RNF96; TF1B; tif1 beta; Tif1b; Tif1beta; TIF1-beta; Transcription intermediary factor 1-beta; transcriptional intermediary factor 1, beta; transcriptional intermediary factor 1-beta; Trim28; tripartite motif; tripartite motif containing 28; tripartite motif protein 28; tripartite motif-containing 28; tripartite motif-containing protein 28

Immunogen:
Recombinant protein corresponding to residues 60-383 of the human TIF1 beta protein.

Quantity:
100 μg

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Target Molecule:
__

Img

Thermo Scientific

MA120245

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Antigen:
Placental Alkaline Phosphatase

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.09% sodium azide

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Flow Cytometry, Immunohistochemistry (Frozen)

Clone:
H17E2

Conjugate:
Unconjugated

Gene Alias:
Alkaline phosphatase placental type; Alkaline phosphatase Regan isozyme; alkaline phosphatase, placental; alkaline phosphatase, placental type; alkaline phosphomonoesterase; ALP; Alp1; ALPP; AP-TNAP; DOA1; FLJ11281; FLJ40094; FLJ61142; FLJ93059; Germ-cell alkaline phosphatase; glycerophosphatase; HOPS; MGC161443; MGC167935; nagao Isozyme; P PLAP; PALP; PLA2P; PLAA; placental alkaline phosphatase 1; placental heat-stable alkaline phosphatase; PLAP; PLAP1; PLAP-1; rCG23846-like; Regan isozyme; TNAP; TNSALP

Immunogen:
Human placental membrane.

Quantity:
100 μg

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Target Molecule:
__