MA123232
FOXO1 Monoclonal Antibody (4E7), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MA123232-Each-of-1 | In Stock | ₹ 45,646.26 |
MA123232 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,646.26
GST (18%): ₹ 8,216.327
Total Price: ₹ 53,862.587
Antigen
FOXO1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative; pH 7.4
Gene Accession No.
Q12778
Gene Symbols
FOXO1
Immunogen
Amino acids 242-655 of FKHR expressed in E. coli.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Immunohistochemistry, Western Blot
Clone
4E7
Conjugate
Unconjugated
Gene
FOXO1
Gene Alias
Afxh; AI876417; FKH1; FKHR; Fkhr1; forkhead box O1; forkhead box O1 a; forkhead box O1a; forkhead box O1A (rhabdomyosarcoma); forkhead box protein O1; forkhead box protein O1; LOW QUALITY PROTEIN: forkhead box protein O1; forkhead box protein O1A; Forkhead box protein O1-A; Forkhead in rhabdomyosarcoma; forkhead protein 1; forkhead protein FKHR; forkhead, Drosophila, homolog of, in rhabdomyosarcoma; fox family transcription factor FoxO1a.1; FOX01A; foxhead box protein O1-A; foxo1; FOXO1A; FoxO1a.1; member of FKHR-subclass forkhead/winged helix family; zgc:153388
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
2308
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Predicted molecular weight: ∽70 kDa
- Positive Control: Cos 1 cells transfected with human FKHR
- FOXO1 (FKHR, ForKHead Box 01) is a member in a subfamily of the forkhead homeotic gene family of transcription factors
- Recent experiments have shown that FOXO1 can act as either a coactivator or a corepressor of nuclear receptor activity that is mediated through the LXXLL motif found in the carboxyl terminal region of the FKHR protein
- Association of FOXO1 with PAX3 has been implicated in alveolar rhabdomyosarcoma
- Recent studies link the anti-tumor activity of FOXO1, the process of autophagy and myogenic growth and differentiation
- FOXO1 is the main target of insulin signaling that regulated the metabolic homeostasis in response to oxidative stress
- FOXO1 binds to the insulin response element (IRE) with consensus sequence 5'-TT[G/A]TTTTG-3' and the related Daf-16 family binding element (DBE) with consensus sequence 5'- TT[G/A]TTTAC-3'
- FOXO1 is a regulator of redox balance, osteoblast numbers and controls bone mass
- Further, FOXO1 orchestrates the endocrine function of the skeleton in regulating glucose metabolism, and suppresses the transcriptional activity of RUNX2, an upstream activator of osteocalcin/BGLAP
- In hepatocytes, FOXO1 promotes gluconeogenesis by acting together with PPARGC1A to activate the expression of genes such as IGFBP1, G6PC and PPCK1
- FOXO1 is an important regulator of cell death acting downstream of CDK1, PKB/AKT1 and SKT4/MST1.
Compare Similar Items
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Antigen: FOXO1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative; pH 7.4
Gene Accession No.: Q12778
Gene Symbols: FOXO1
Immunogen: Amino acids 242-655 of FKHR expressed in E. coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Immunohistochemistry, Western Blot
Clone: 4E7
Conjugate: Unconjugated
Gene: FOXO1
Gene Alias: Afxh; AI876417; FKH1; FKHR; Fkhr1; forkhead box O1; forkhead box O1 a; forkhead box O1a; forkhead box O1A (rhabdomyosarcoma); forkhead box protein O1; forkhead box protein O1; LOW QUALITY PROTEIN: forkhead box protein O1; forkhead box protein O1A; Forkhead box protein O1-A; Forkhead in rhabdomyosarcoma; forkhead protein 1; forkhead protein FKHR; forkhead, Drosophila, homolog of, in rhabdomyosarcoma; fox family transcription factor FoxO1a.1; FOX01A; foxhead box protein O1-A; foxo1; FOXO1A; FoxO1a.1; member of FKHR-subclass forkhead/winged helix family; zgc:153388
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 2308
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
FOXO1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative; pH 7.4
Gene Accession No.:
Q12778
Gene Symbols:
FOXO1
Immunogen:
Amino acids 242-655 of FKHR expressed in E. coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunohistochemistry, Western Blot
Clone:
4E7
Conjugate:
Unconjugated
Gene:
FOXO1
Gene Alias:
Afxh; AI876417; FKH1; FKHR; Fkhr1; forkhead box O1; forkhead box O1 a; forkhead box O1a; forkhead box O1A (rhabdomyosarcoma); forkhead box protein O1; forkhead box protein O1; LOW QUALITY PROTEIN: forkhead box protein O1; forkhead box protein O1A; Forkhead box protein O1-A; Forkhead in rhabdomyosarcoma; forkhead protein 1; forkhead protein FKHR; forkhead, Drosophila, homolog of, in rhabdomyosarcoma; fox family transcription factor FoxO1a.1; FOX01A; foxhead box protein O1-A; foxo1; FOXO1A; FoxO1a.1; member of FKHR-subclass forkhead/winged helix family; zgc:153388
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
2308
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: SAFB
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: D3YXK2, Q15424
Gene Symbols: SAFB
Immunogen: A synthetic peptide corresponding to amino acids 345-357 (PEARDSKEDGRKF) of the human HET protein.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG1
Applications: Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot
Clone: 6F7
Conjugate: Unconjugated
Gene: SAFB
Gene Alias: 3110021E02Rik; 5330423C17Rik; AU018122; D18386; DKFZp779C1727; E130307D12; glutathione S-transferase fusion protein; HAP; heat-shock protein (HSP27) estrogen response element and TATA box-binding protein; HET; Hsp27 ERE-TATA binding protein; HSP27 ERE-TATA-binding protein; HSP27 estrogen response element-TATA box-binding protein; SAB-B1; Safb; SAF-B; Safb1; SAF-B1; scaffold attachment factor B; scaffold attachment factor B1
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 224903, 6294
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
SAFB
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
D3YXK2, Q15424
Gene Symbols:
SAFB
Immunogen:
A synthetic peptide corresponding to amino acids 345-357 (PEARDSKEDGRKF) of the human HET protein.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot
Clone:
6F7
Conjugate:
Unconjugated
Gene:
SAFB
Gene Alias:
3110021E02Rik; 5330423C17Rik; AU018122; D18386; DKFZp779C1727; E130307D12; glutathione S-transferase fusion protein; HAP; heat-shock protein (HSP27) estrogen response element and TATA box-binding protein; HET; Hsp27 ERE-TATA binding protein; HSP27 ERE-TATA-binding protein; HSP27 estrogen response element-TATA box-binding protein; SAB-B1; Safb; SAF-B; Safb1; SAF-B1; scaffold attachment factor B; scaffold attachment factor B1
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
224903, 6294
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: NBS1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 20% glycerol and no preservative; pH 7
Gene Accession No.: O60934, Q9JIL9, Q9R207
Gene Symbols: NBN
Immunogen: The complete coding region of the human p95/NBS1 expressed in E. coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG1
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
Clone: 1D7
Conjugate: Unconjugated
Gene: NBN
Gene Alias: AT V1; AT V2; ATV; AT-V1; AT-V2; Cell cycle regulatory protein p95; FLJ10155; I79_012607; MGC87362; Nbn; NBS; NBS1; nibrin; Nijmegen breakage syndrome 1 (nibrin); Nijmegen breakage syndrome protein 1; Nijmegen breakage syndrome protein 1 homolog; OTTHUMP00000204088; P95; p95 protein of the MRE11/RAD50 complex; p95-NBS1
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 27354, 4683, 85482
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
NBS1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 20% glycerol and no preservative; pH 7
Gene Accession No.:
O60934, Q9JIL9, Q9R207
Gene Symbols:
NBN
Immunogen:
The complete coding region of the human p95/NBS1 expressed in E. coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot
Clone:
1D7
Conjugate:
Unconjugated
Gene:
NBN
Gene Alias:
AT V1; AT V2; ATV; AT-V1; AT-V2; Cell cycle regulatory protein p95; FLJ10155; I79_012607; MGC87362; Nbn; NBS; NBS1; nibrin; Nijmegen breakage syndrome 1 (nibrin); Nijmegen breakage syndrome protein 1; Nijmegen breakage syndrome protein 1 homolog; OTTHUMP00000204088; P95; p95 protein of the MRE11/RAD50 complex; p95-NBS1
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
27354, 4683, 85482
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: RAD51
Classification: Monoclonal
Concentration: 1.0 mg/mL
Formulation: PBS with no preservative; pH 7
Gene Accession No.: P37383, Q06609, Q08297
Gene Symbols: Rad51
Immunogen: Full length Rad51 protein (amino acids 1-338) expressed in E. coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Chicken, Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG2b
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Proximity Ligation Assay, Western Blot
Clone: 14B4
Conjugate: Unconjugated
Gene: Rad51
Gene Alias: AV304093; BRCA1/BRCA2-containing complex, subunit 5; BRCC5; DNA repair protein RAD51; DNA repair protein RAD51 homolog 1; DNA repair protein RAD51 homolog A; DNA repair protein rhp51; FANCR; homolog to S.cerevisiae; HRAD51; HsRad51; HsT16930; MGC128559 protein; MRMV2; MUT5; rad51; RAD51 homolog; RAD51 homolog (RecA homolog); RAD51 homolog (RecA homolog, E. coli); RAD51 homolog A; RAD51 recombinase; RAD51 recombinase L homeolog; rad51.1; rad51.L; rad51-1; RAD51A; rad51-a; rad51-b; Reca; RecA family recombinase Rhp51; RecA, E. coli, homolog of; RecA-like protein; recombinase RAD51; recombination protein A; RGD1563603; rhp51; SPAC644.14c; wu:fb38e12; xrad51; XRad51.1; YER095W; zgc:77754
Host Species: Mouse
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 19361, 396086, 499870, 5888
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
RAD51
Classification:
Monoclonal
Concentration:
1.0 mg/mL
Formulation:
PBS with no preservative; pH 7
Gene Accession No.:
P37383, Q06609, Q08297
Gene Symbols:
Rad51
Immunogen:
Full length Rad51 protein (amino acids 1-338) expressed in E. coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Chicken, Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Proximity Ligation Assay, Western Blot
Clone:
14B4
Conjugate:
Unconjugated
Gene:
Rad51
Gene Alias:
AV304093; BRCA1/BRCA2-containing complex, subunit 5; BRCC5; DNA repair protein RAD51; DNA repair protein RAD51 homolog 1; DNA repair protein RAD51 homolog A; DNA repair protein rhp51; FANCR; homolog to S.cerevisiae; HRAD51; HsRad51; HsT16930; MGC128559 protein; MRMV2; MUT5; rad51; RAD51 homolog; RAD51 homolog (RecA homolog); RAD51 homolog (RecA homolog, E. coli); RAD51 homolog A; RAD51 recombinase; RAD51 recombinase L homeolog; rad51.1; rad51.L; rad51-1; RAD51A; rad51-a; rad51-b; Reca; RecA family recombinase Rhp51; RecA, E. coli, homolog of; RecA-like protein; recombinase RAD51; recombination protein A; RGD1563603; rhp51; SPAC644.14c; wu:fb38e12; xrad51; XRad51.1; YER095W; zgc:77754
Host Species:
Mouse
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
19361, 396086, 499870, 5888
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid